Gene News and Research

Latest Gene News and Research

FDA approves Sprycel for treatment of adults with Ph+ CP-CML

The U.S. Food and Drug Administration today approved a new indication for Sprycel (dasatinib) for the treatment of a rare blood cancer when it is first diagnosed. The cancer, called Philadelphia chromosome positive chronic phase chronic myeloid leukemia (Ph+ CP-CML), is a slowly progressing blood and bone marrow disease linked to a genetic abnormality.

29 Oct 2010

Inefficient suppression of DUX4 gene causes facioscapulohumeral dystrophy: Study

An international team of researchers led by an investigator from Fred Hutchinson Cancer Research Center has made a second critical advance in determining the cause of a common form of muscular dystrophy known as facioscapulohumeral dystrophy, or FSHD.

29 Oct 2010

StemCells initiates HuCNS-SC second clinical trial for Batten disease in children

StemCells, Inc. announced today that it has initiated a second clinical trial of its HuCNS-SC product candidate (purified human neural stem cells) in neuronal ceroid lipofuscinosis (NCL, also often referred to as Batten disease), a fatal neurodegenerative disorder in children.

29 Oct 2010

Pain Therapeutics third quarter net loss decreases from $1.3 million to $1.0 million

Pain Therapeutics, Inc. a biopharmaceutical company, today reported financial results for its third quarter of fiscal year 2010.

29 Oct 2010

Common psychiatric drugs could slow dementia

Researchers say commonly used psychiatric drugs could be effective in slowing the progression of certain types of dementia. Dr John Kwok and colleagues from Neuroscience Research Australia have discovered a mutant gene that causes abnormal proteins build up in the brains of people with frontotemporal dementia, a disease that affects people in their 50s and 60s.

28 Oct 2010

Celgene third quarter non-GAAP total revenue increases 31% to $908 million

Celgene Corporation announced non-GAAP net income of $349.9 million, or non-GAAP diluted earnings per share of $0.75 for the quarter ended September 30, 2010.

28 Oct 2010

QLT expands QLT091001 Phase 1b LCA study to include patients with Retinitis Pigmentosa

QLT Inc. today announced expansion of the Phase 1b clinical proof-of-concept study of QLT091001 in the treatment of Leber Congenital Amaurosis (LCA) to include patients with Retinitis Pigmentosa (RP), a set of hereditary retinal diseases demonstrating clinical features similar to LCA.

28 Oct 2010

World's largest research initiative to mutate all mouse genes

The world's largest research initiative to mutate all mouse genes is now able to reach the summit because the ambitious EUCOMMTOOLS project started on October 1, 2010. This project is being coordinated by Helmholtz Zentrum München and will finalize the groundwork for the analysis of all mouse gene functions. The findings will contribute to a better understanding of the pathogenesis of widespread diseases such as Alzheimer's, depression, diabetes, chronic lung diseases or cancer.

28 Oct 2010

USPTO rejects patent claims asserted against Precision BioSciences

Precision BioSciences, Inc., today announced that the United States Patent and Trademark Office (PTO) has issued Final Decisions and Right of Appeal Notices in the reexamination proceedings for U.S. Pat. Nos. 6,833252, 7,214,536, 6,610,545 and 7,309,605 that are owned by the Institut Pasteur and the Universite Pierre et Marie Curie, and licensed to Cellectis, SA (ALCLS).

28 Oct 2010

Pfizer announces publication of crizotinib data for NSCLC patients in New England Journal of Medicine

Pfizer Inc. announced today the publication of data showing that 57 percent of ALK-positive advanced non-small cell lung cancer (NSCLC) patients treated with crizotinib (PF-02341066), an investigational oral anaplastic lymphoma kinase (ALK) inhibitor, had either a complete (one patient) or partial (46 patients) response to treatment. Data from 82 patients in this Part 2 expansion cohort of the Phase 1 study were published in the October 28 issue of the New England Journal of Medicine.

28 Oct 2010

AnaptysBio announces issuance of two new patents for SHM-XEL platform

AnaptysBio, Inc., a privately-held therapeutic antibody platform and product company, announced the issuance of patents in the US and Europe that provide additional coverage for its SHM-XEL platform. These patents extend AnaptysBio's leadership in the use of somatic hypermutation (SHM) for the discovery and optimization of antibodies and other proteins.

28 Oct 2010

Epigenomics presents data on Septin9 biomarker clinical study for colorectal cancer at UEGW

Epigenomics AG, the cancer diagnostics company, announced that new data obtained in a clinical study with the Company's proprietary Septin9 biomarker for the blood-based detection of colorectal cancer, were presented yesterday at the 18th United European Gastroenterology Week (UEGW) in Barcelona, Spain.

28 Oct 2010

IntegraGen to open subsidiary in Cambridge, Massachusetts

IntegraGen, Inc., a French biotechnology company dedicated to gene discovery and the development of molecular diagnostic products and services, announced today that it is expanding its operations by opening a U.S. subsidiary headquartered in Cambridge, Massachusetts that will support the company's clinical research initiatives focused on the early identification of children at risk of autism. IntegraGen will open the new office on November 1, 2010.

28 Oct 2010

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Today in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

28 Oct 2010

H5N1 lethality gene Replikin Count continues to rise in 2010

BioRadar™ software correctly predicted the 2009 H1N1 (Swine Flu) outbreak a year in advance. The same rise in Replikin Count of these genomic Replikin genes, this time in the H5N1 (Bird Flu) virus, may similarly warn of the coming of severe outbreaks in H5N1.

28 Oct 2010

New oral drug shrinks IMT sarcoma driven by abnormally activated protein

A new oral drug caused dramatic shrinkage of a patient's rare, aggressive form of soft-tissue cancer that was driven by an abnormally activated protein, physician-scientists from Dana-Farber Cancer Institute report in the Oct. 28 issue of the New England Journal of Medicine.

28 Oct 2010

New findings suggest way to treat lung diseases

A new study of an exotic, infectious virus that has caused three recent outbreaks in the United States reveals clues to how the virus might damage lungs during infection. The findings also suggest possible new ways to treat lung diseases in humans.

28 Oct 2010

Omnyx initiates research testing of digital pathology platform

GE Healthcare and UPMC announced today that their imaging joint venture, Omnyx, is initiating clinical research testing of a breakthrough digital pathology platform that is expected to help transform the 125-year-old practice of pathologists using glass slides.

28 Oct 2010

University of Manchester receives Wellcome Trust grant for five-year study

A team investigating how genes respond to hormonal changes and inflammation has been awarded a Wellcome Trust grant of 1.24 million for a five-year study

From The University of Manchester 28 Oct 2010

New computational techniques to overcome obstacles in hard-to-study genes

Scientists have invented methods to scout the human genome's repetitive landscapes, where DNA sequences are highly identical and heavily duplicated. These advances, as reported today in Science, can identify subtle but important differences among people in the number and content of repeated DNA segments.

28 Oct 2010

Gene News and Research

Latest Gene News and Research

FDA approves Sprycel for treatment of adults with Ph+ CP-CML

Inefficient suppression of DUX4 gene causes facioscapulohumeral dystrophy: Study

StemCells initiates HuCNS-SC second clinical trial for Batten disease in children

Pain Therapeutics third quarter net loss decreases from $1.3 million to $1.0 million

Common psychiatric drugs could slow dementia

Celgene third quarter non-GAAP total revenue increases 31% to $908 million

QLT expands QLT091001 Phase 1b LCA study to include patients with Retinitis Pigmentosa

World's largest research initiative to mutate all mouse genes

USPTO rejects patent claims asserted against Precision BioSciences

Pfizer announces publication of crizotinib data for NSCLC patients in New England Journal of Medicine

AnaptysBio announces issuance of two new patents for SHM-XEL platform

Epigenomics presents data on Septin9 biomarker clinical study for colorectal cancer at UEGW

IntegraGen to open subsidiary in Cambridge, Massachusetts

1000 Genomes Project publishes comprehensive map of genetic variations in Nature journal

H5N1 lethality gene Replikin Count continues to rise in 2010

New oral drug shrinks IMT sarcoma driven by abnormally activated protein

New findings suggest way to treat lung diseases

Omnyx initiates research testing of digital pathology platform

University of Manchester receives Wellcome Trust grant for five-year study

New computational techniques to overcome obstacles in hard-to-study genes

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