Gene News and Research

Latest Gene News and Research

Neurologix holds license for gene therapy to treat severe depression

Neurologix, Inc. today announced that a landmark paper, published on October 20th in Science Translational Medicine demonstrating the importance of the p11 gene in modulating depression in mice, utilized a gene therapy approach to reverse depression in mice for which the Company holds exclusive development rights. Based on the findings reported in the paper, gene therapy may have potential as a new treatment option for people who suffer from severe depression.

26 Oct 2010

Researchers identify signaling pathway that promotes metastasis of pediatric bone cancer

Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer. Their research showed that the Notch pathway and Hes1 gene play a key role in promoting the metastasis of osteosarcoma, the most common form of bone cancer in children.

26 Oct 2010

Viral microRNA allows EBV to hide within cells and evade immune system

While most commonly associated with mononucleosis, Epstein-Barr virus (EBV) has been linked to many diseases that affect people long after the initial infection takes place, including some forms of cancer. In the current issue of the Journal of Biological Chemistry, scientists at The Wistar Institute describe how viral microRNA - small segments of RNA that suppress the effects of gene activity - allows EBV to hide within cells and evade the immune system.

26 Oct 2010

Alzheimer's Association receives Innovator Award in Best Integrated Marketing Campaign category

Alzheimer's Association, the leading U.S. voluntary health organization in Alzheimer care, support and research, was presented with an Innovator Award in the Best Integrated Marketing Campaign category for their successful marketing campaign to promote the organization's Action Summit 2010.

26 Oct 2010

Study on gene variant associated with narcolepsy

Ever wonder why some people breeze along on four hours of sleep when others can barely function? It may be in our genes, according to new research and an accompanying editorial published in the October 26, 2010, print issue of Neurology®, the medical journal of the American Academy of Neurology.

26 Oct 2010

Eye-gaze technology opens world of communication for Rett Syndrome children

Special eye-gaze technology now being used in the Department of Neurology at The Children's Hospital at Montefiore (CHAM) is revealing the hidden, inner world of children who have Rett Syndrome, a rare and severe autism spectrum disorder that primarily affects little girls. It is a neurological disease in which mobility and autonomic functions are severely impaired, seizures and orthopedic problems are common, and the children lose functional hand use and the ability to speak.

26 Oct 2010

Researchers shed new light on genetic factors that increase common disorders of pregnancy

A team of researchers, led by Ashley Moffett, at the University of Cambridge, United Kingdom, has shed new light on genetic factors that increase susceptibility to and provide protection from common disorders of pregnancy, specifically recurrent miscarriage, preeclampsia, and fetal growth restriction.

26 Oct 2010

CINJ researcher receives Clinical/Basic Science Research Award

Amar Rewari, MD, MBA, a researcher from The Cancer Institute of New Jersey (CINJ), has been chosen to receive the Clinical Award in Clinical/Basic Science Research at the 52nd Annual Meeting of The American Society for Radiation Oncology (ASTRO) in San Diego next month. CINJ is a Center of Excellence of UMDNJ-Robert Wood Johnson Medical School.

26 Oct 2010

Examining genetic material of egg cells may inform about embryos health

Fertility procedures such as in vitro fertilization (IVF) require a couple and the doctor to place the risky bet that the multiple eggs they choose to fertilize will produce an embryo that will thrive in the uterus. Researchers cannot biopsy eggs directly because that would destroy them, but a new discovery by professors at Brown University and Women & Infants Hospital could lead to new insights about how eggs develop and ultimately inform judgments about how the embryos they produce will fare. The idea is to examine the genetic material the egg cells discarded when they were first forming, to see which genes they were expressing.

26 Oct 2010

Duke Center releases online atlas of ultra-high-resolution mouse brain

The most detailed magnetic resonance images ever obtained of a mammalian brain are now available to researchers in a free, online atlas of an ultra-high-resolution mouse brain, thanks to work at the Duke Center for In Vivo Microscopy.

26 Oct 2010

Genetic code of sudden death cardiac killer cracked

Researchers in Newfoundland have cracked the genetic code of a sudden death cardiac killer.

26 Oct 2010

Enrollment complete in ViroPharma's Phase 2 study evaluating subcutaneous delivery of Cinryze

ViroPharma Incorporated today announced that it has completed enrollment in its Phase 2 study evaluating subcutaneous delivery of Cinryze™ (C1esterase inhibitor [human]). This multi-center, open-label, multi-dose Phase 2 study is designed to evaluate the safety, pharmacokinetics and pharmacodynamics of subcutaneous versus intravenous administration of Cinryze in adolescent and adult subjects with hereditary angioedema (HAE).

25 Oct 2010

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Gene Security Network (GSN) announced today that it has initiated enrollment for a prospective randomized trial in collaboration with Ferring Pharmaceuticals to evaluate the impact of GSN's advanced preimplantation genetic diagnosis (PGD) with Parental Support™ on pregnancy and implantation rates in IVF.

25 Oct 2010

Gene therapy may reverse pulmonary hypertension

A Heart and Stroke Foundation researcher has discovered what could be the first truly effective breakthrough in the diagnosis and treatment of pulmonary hypertension, a devastating, life-threatening condition which results in an enlargement of the heart.

25 Oct 2010

New gene therapy product reduces plasma cholesterol levels

Amsterdam Molecular Therapeutics (AMT) Holding N.V. a leader in the development of gene based therapies, today announced that its gene therapy product incorporating siRNA sequences into microRNA scaffolds to silence Apolipoprotein B100 (AAV-miApoB) was able to significantly lower plasma cholesterol levels in vivo over a period of 18 weeks. These preliminary results suggest that this approach could lead to a treatment for high cholesterol in humans

25 Oct 2010

Inovio announces publication of minimally-invasive intradermal device in journal Gene Therapy

Inovio Pharmaceuticals, Inc. a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that a peer-reviewed research article describing the development of a new intradermal, minimally-invasive DNA vaccine delivery device was published in the prestigious journal Gene Therapy.

25 Oct 2010

NIH awards $3.9M for Fanconi anemia research

The National Institutes of Health has awarded a three-year, $3.9 million grant to Children's Hospital Boston researchers and their colleagues to develop a therapy to treat Fanconi anemia, a fatal genetic blood disease.

25 Oct 2010

BAFF protein can promote aggressive leukemia and lymphomas

Chronic lymphocytic leukemia (CLL) cells survive and thrive not just by their own innate wiles, but by also acquiring aid and support from host cells in their surrounding environment.

25 Oct 2010

Researchers discover microglia cells originates prior to birth during embryonic life

Mount Sinai researchers have discovered that microglia, the immune cells that reside in the brain, have a unique origin and are formed shortly after conception. It was previously thought that microglia originated at the same time as macrophages, which are other immune cells that are thought to develop at birth. This groundbreaking discovery has the potential to lead to future treatments of degenerative brain diseases such as Alzheimer's and autoimmune diseases such as multiple sclerosis. The study is published online October 21 in Science Express.

25 Oct 2010

Shrink announces agreement to produce high content screening tool for biotech R&D subsidiary

Shrink Nanotechnologies, Inc. an innovative nanotechnology company developing products and licensing opportunities in the alternative energy industry, medical diagnostics and sensors and biotechnology research and development tools businesses, announced today that it has entered into an agreement to produce a high content screening tool for its biotech R&D subsidiary, Shrink Chips LLC.

25 Oct 2010

Gene News and Research

Latest Gene News and Research

Neurologix holds license for gene therapy to treat severe depression

Researchers identify signaling pathway that promotes metastasis of pediatric bone cancer

Viral microRNA allows EBV to hide within cells and evade immune system

Alzheimer's Association receives Innovator Award in Best Integrated Marketing Campaign category

Study on gene variant associated with narcolepsy

Eye-gaze technology opens world of communication for Rett Syndrome children

Researchers shed new light on genetic factors that increase common disorders of pregnancy

CINJ researcher receives Clinical/Basic Science Research Award

Examining genetic material of egg cells may inform about embryos health

Duke Center releases online atlas of ultra-high-resolution mouse brain

Genetic code of sudden death cardiac killer cracked

Enrollment complete in ViroPharma's Phase 2 study evaluating subcutaneous delivery of Cinryze

GSN initiates trial of microarray PGD on pregnancy and implantation rates in IVF

Gene therapy may reverse pulmonary hypertension

New gene therapy product reduces plasma cholesterol levels

Inovio announces publication of minimally-invasive intradermal device in journal Gene Therapy

NIH awards $3.9M for Fanconi anemia research

BAFF protein can promote aggressive leukemia and lymphomas

Researchers discover microglia cells originates prior to birth during embryonic life

Shrink announces agreement to produce high content screening tool for biotech R&D subsidiary

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