Gene News and Research

Latest Gene News and Research

HSF1A stimulates more protein chaperones and reduces protein misfolding

Scientists at Duke University Medical Center have found some compounds that improve a cell's ability to properly "fold" proteins and could lead to promising drugs for degenerative nerve diseases, including Huntington's disease, Alzheimer's disease and Parkinson's disease.

20 Jan 2010

Researchers show how gliomas can evade drugs aimed at blocking EGFR

Researchers at the Ludwig Institute for Cancer Research (LICR) at the University of California, San Diego School of Medicine and Moores UCSD Cancer Center have shown one way in which gliomas, a deadly type of brain tumor, can evade drugs aimed at blocking a key cell signaling protein, epidermal growth factor receptor (EGFR),that is crucial for tumor growth.

20 Jan 2010

Gene variant predisposes humans to develop acute myeloid leukemia, says study

A large international research group led by Dr. Tarik M-r-y, a researcher at the Institut de recherches cliniques de Montr-al (IRCM), has discovered that a variant of the gene "Growth Factor Independence 1" (GFI1) predisposes humans to develop acute myeloid leukemia (AML), a certain subtype of blood cancer.

20 Jan 2010

Alnylam Pharmaceuticals presents data on multiple therapeutic programs at RNAi Symposium

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today announced that it presented data from multiple pre-clinical and clinical programs at the “RNA Silencing: Mechanism, Biology, and Application” Keystone Symposium held January 14-19, 2010 in Keystone, Colorado. Alnylam and its collaborators presented data from Alnylam’s therapeutic programs including transthyretin (TTR)-mediated amyloidosis and Huntington’s disease, as well as new data on delivery approaches for the systemic delivery of RNAi therapeutics.

20 Jan 2010

European Breast Cancer Conference in Barcelona, Spain

The 7th European Breast Cancer Conference (EBCC-7) will be held in Barcelona, Spain (Centre Convencions Internacional (CCIB - FORUM), Rambla Prim 1-17, ES-08019) from Wednesday 24 - Saturday 27 March 2010.

20 Jan 2010

Combination treatment strategies may benefit patients with non-small cell lung cancer

Even when their tumors are shrinking in response to therapy, some non-small cell lung cancer (NSCLC) patients have a scattering of cancer cells that are undeterred by the drug, causing the tumor to resume its growth, Dana-Farber Cancer Institute and Massachusetts General Hospital (MGH) Cancer Center scientists report in the January issue of Cancer Cell.

20 Jan 2010

Study shows an intriguing relationship between cancer-related genes and schizophrenia susceptibility

People who inherit a specific form of a gene that puts them on a road to schizophrenia may be protected against some forms of cancer, according to a new study by scientists at The Feinstein Institute for Medical Research.

20 Jan 2010

Researchers propose a new model for breast cell differentiation

A study by researchers at Tufts University School of Medicine, the Sackler School of Graduate Biomedical Sciences at Tufts, and Tufts Medical Center improves our current understanding of the origins of breast cancer. The

19 Jan 2010

Repeated exposure to tobacco smoke makes lung cancer much worse

Repeated exposure to tobacco smoke makes lung cancer much worse, and one reason is that it steps up inflammation in the lung. Scientists at the University of California, San Diego School of Medicine have found that mice with early lung cancer lesions that were repeatedly exposed to tobacco smoke developed larger tumors - and developed tumors more quickly - than unexposed animals.

19 Jan 2010

Leafy green vegetables, folate and multivitamins can prevent lung cancer in smokers

Leafy green vegetables, folate, and some multivitamins could serve as protective factors against lung cancer in current and former smokers, according to a study that is a first step in understanding a complex association.

19 Jan 2010

GenVec and Novartis collaborate to develop novel treatments for hearing loss and balance disorders

GenVec and Novartis will collaborate to discover and develop novel treatments for hearing loss and balance disorders. Preclinical results suggest that delivery of the atonal gene using GenVec's innovative adenovector technology may have the potential to restore hearing and balance function.

19 Jan 2010

New functions in an enzyme can develop through point mutation

A new study by a research team at Uppsala University shows how new functions can develop in an enzyme. This can explain, for example, how resistance to toxins can occur so simply. The findings are now being published in the Journal of Biological Chemistry.

19 Jan 2010

Findings pave way for designing better antibiotics to target bacterial transcription machinery

A new study led by researchers at NYU Langone Medical Center is shedding new light on the action of Rho, a key regulatory protein in E. coli and many other bacteria.

19 Jan 2010

Anthem Blue Cross and California Regional Hospital Associations join in patient safety collaborative

Anthem Blue Cross, along with California's three regional Hospital Associations, and the National Health Foundation, announced today that they are joining together in a three-year, 6 million dollar effort to improve the quality and consistency of care Californians receive. The Ronald Reagan UCLA Medical Center hosted the launch of Patient Safety First... a California Partnership for Health, a unique relationship that will save lives, improve the quality of medical care and reduce health care costs to make health care more affordable for the people of California.

19 Jan 2010

Research may pave for further studies on various human skin disorders

The leopard cannot change its spots, nor can the tiger change its stripes, but a new research report published in the January 2009 issue of the journal GENETICS tells us something about how cats end up with their spots and stripes

18 Jan 2010

Breast cancer and ovarian cancer tests not appropriate for all women, say experts

A genetic mutation can significantly increases a woman's risk of developing breast cancer and ovarian cancer. But does that mean everyone should be tested?

18 Jan 2010

New genetic risk factor for Parkinson's disease identified

An international team of doctors and human geneticists has identified a new genetic risk factor for Parkinson's disease. The institutions involved in the study were the Institute of Human Genetics of Helmholtz Zentrum München and Technische Universität München, the Neurological Clinic of Ludwig-Maximilians-Universität Munich (LMU) and the Mitochondrial Research Group of Newcastle University, Newcastle upon Tyne, UK.

18 Jan 2010

Molecules capable of reversing brain abnormalities in PD identified

Scientists identified several molecules capable of reversing the brain abnormalities of Parkinson's disease (PD), while also uncovering new clues for its origin in a study just published in the journal Disease Models and Mechanisms. PD is characterised by abnormal deposits of a brain protein called alpha-synuclein throughout the damaged brain regions, but exactly what they do there is not clear. The fact that their numbers and spreading are associated disease progression has made them, however, a major point of interest in PD research.

18 Jan 2010

Down syndrome and Alzheimer's disease are the same

Nearly 20 years ago Huntington Potter kicked up a storm of controversy with the idea that Down syndrome and Alzheimer's were the same disease. Now the evidence is in: He was right.

18 Jan 2010

Sirnaomics certifies polypeptide nanoparticle technology

Sirnaomics, Inc. (www.sirnaomics.com) announced today that the company has licensed a polypeptide nanoparticle technology invented by Professor A. James Mixson of University of Maryland Medical School.

18 Jan 2010

Gene News and Research

Latest Gene News and Research

HSF1A stimulates more protein chaperones and reduces protein misfolding

Researchers show how gliomas can evade drugs aimed at blocking EGFR

Gene variant predisposes humans to develop acute myeloid leukemia, says study

Alnylam Pharmaceuticals presents data on multiple therapeutic programs at RNAi Symposium

European Breast Cancer Conference in Barcelona, Spain

Combination treatment strategies may benefit patients with non-small cell lung cancer

Study shows an intriguing relationship between cancer-related genes and schizophrenia susceptibility

Researchers propose a new model for breast cell differentiation

Repeated exposure to tobacco smoke makes lung cancer much worse

Leafy green vegetables, folate and multivitamins can prevent lung cancer in smokers

GenVec and Novartis collaborate to develop novel treatments for hearing loss and balance disorders

New functions in an enzyme can develop through point mutation

Findings pave way for designing better antibiotics to target bacterial transcription machinery

Anthem Blue Cross and California Regional Hospital Associations join in patient safety collaborative

Research may pave for further studies on various human skin disorders

Breast cancer and ovarian cancer tests not appropriate for all women, say experts

New genetic risk factor for Parkinson's disease identified

Molecules capable of reversing brain abnormalities in PD identified

Down syndrome and Alzheimer's disease are the same

Sirnaomics certifies polypeptide nanoparticle technology

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up