Gene News and Research

Latest Gene News and Research

Exploring the role of SNPs in early diagnosis of coronary microvascular dysfunction

A new review highlights the potential role of single nucleotide polymorphisms (SNPs) in improving the early diagnosis and targeted intervention of coronary microvascular dysfunction (CMD)—a condition linked to myocardial ischemia despite the absence of major artery blockages.

26 Feb 2025

Microphysiological systems in drug discovery

NewsMedical speaks with CN Bio about the translatability between in vitro organ-on-a-chip (OOC) models, microphysiological systems, and their in vivo counterparts.

From CN Bio Innovations Ltd 26 Feb 2025

Single-cell analysis reveals key chondrocyte subpopulations in osteoarthritis

Chondrocytes are specialized cells that are essential for cartilage maintenance and repair, and their dysfunction is central to the development of joint diseases like osteoarthritis (OA).

26 Feb 2025

Can coffee push back Parkinson’s? New study uncovers key genetic link

Higher coffee consumption is causally linked to delayed onset of Parkinson’s disease but does not affect disease risk or progression, according to a Mendelian randomization study.

25 Feb 2025

Discovery of new bat flu strain with potential to infect other species

Scientists have identified a novel influenza A virus (H18N12) in fishing bats in the Colombian Caribbean, revealing genetic reassortment events that impact viral adaptability and host transmission.

25 Feb 2025

Pig kidney transplant patient completes recovery and returns home

Three months after her breakthrough surgery at NYU Langone Health, Towana Looney, the longest-living recipient of a genetically engineered pig kidney, is headed back home to Alabama.

25 Feb 2025

Researchers challenge previous understanding of tumor growth in NF-1

Despite what was previously thought, new research has shown that genetic changes alone cannot explain why and where tumors grow in those with genetic condition neurofibromatosis type 1 (NF-1).

25 Feb 2025

Mass General Brigham study uncovers 16 novel Alzheimer's risk genes

Investigators from Mass General Brigham have conducted a multi-ancestry, whole genome sequencing association study of Alzheimer's disease and found evidence for 16 new susceptibility genes, expanding the study of Alzheimer's disease in underrepresented groups.

25 Feb 2025

Researchers create mycobacteria with kill switches to improve TB vaccine safety

Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.

25 Feb 2025

Study explains why misplaced neurons in the brain become overactive

Research reveals why misplaced neurons in the brain are overactive and lead to developmental disorders.

25 Feb 2025

Early lung cancer diagnosis improved with ctDNA methylation biomarkers

Early diagnosis of lung cancer is a critical priority in clinical practice. It may help reduce the rate of lung-cancer-related mortality, extend disease-free survival, and allow patients to live without ongoing medical interventions and complications.

25 Feb 2025

Review highlights next-generation cancer therapies targeting PIK3CA mutations

A newly published review in Genes & Diseases explores the oncogenic activation of PIK3CA in cancer and highlights emerging targeted therapies designed to improve treatment efficacy while reducing side effects.

25 Feb 2025

New insights into mTOR pathway offer hope for diabetic nephropathy treatment

A newly published study in Genes & Diseases highlights the crucial role of the mammalian target of rapamycin (mTOR) pathway in the progression of diabetic nephropathy (DN) and explores its potential as a therapeutic target.

25 Feb 2025

Common medications disrupt brain development by affecting sterol biosynthesis

In a peer-reviewed Perspective (review) article, researchers at the University of Nebraska Medical Center have uncovered concerning evidence that commonly prescribed medications may interfere with crucial brain development processes by disrupting sterol biosynthesis.

25 Feb 2025

Study finds strong evidence that bird flu spreads through the air between farms

Researchers provided genetic and meteorological evidence suggesting that windborne transmission of HPAI H5N1 over 8 km is possible, highlighting its role in poultry farm outbreaks.

24 Feb 2025

Study challenges role of BRCA1 mutation in prostate cancer initiation

Mutations in the BRCA1 gene that are either inherited (germline) or acquired (somatic) might not be key to the initiation of prostate cancer, as previously thought, suggests the first study of its kind, published online in the open access journal BMJ Oncology.

24 Feb 2025

Researchers uncover a surprising layer of complexity in aldosterone-producing tumors

Kyushu University researchers have uncovered a surprising layer of complexity in aldosterone-producing adenomas (APAs)-adrenal gland tumors that drive high blood pressure.

24 Feb 2025

Study uncovers pathway behind age-related degeneration of eye glands

A team led by Mount Sinai researchers has identified stem cell populations and mechanisms underlying age-related degeneration in glands that are vital to eye function.

24 Feb 2025

CMV infection found to worsen necrotizing enterocolitis in preterm infants

Researchers say they found that infection with a common virus that can be transmitted from mother to fetus before birth significantly worsens an often-fatal complication of premature birth called necrotizing enterocolitis (NEC) in experiments with mice.

24 Feb 2025