Genetics News and Research

Latest Genetics News and Research

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

Study shows environment's pivotal role in healthy aging and disease prevention

Study explores new geroscience tools for studying the impact of environmental factors on aging, aiming to delay age-related diseases and disabilities. It highlights how non-genetic factors, like environmental toxins and socio-economic conditions, significantly influence aging and health outcomes.

13 Nov 2023

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Researchers at Gladstone Institutes have discovered that a rare genetic variant known as the "Christchurch mutation" can block detrimental effects of apolipoprotein E4, the best-established risk factor for the most common form of Alzheimer's disease.

13 Nov 2023

Single injection of new medication effectively eliminates Lp(a) for nearly one year

In the first human trial of a new therapeutic, a single injection of lepodisiran reduced levels of lipoprotein(a), or Lp(a), to undetectable levels for nearly one year, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

In a comprehensive multi-ancestry GWAS meta-analysis, researchers identified 451 risk variants for prostate cancer, including 187 new variants, demonstrating the utility of such studies across diverse populations. This analysis not only increased understanding of genetic risk factors but also differentiated between aggressive and non-aggressive prostate cancer types, underscoring the potential of genetic risk scoring in guiding screening and early detection strategies.

12 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

New research aims to decipher how animals discard half their genes

New research is underway to decipher a fascinating biological puzzle - how some animals can naturally discard more than half of their genetic information during embryonic development.

9 Nov 2023

Tumor-immune interactions predict treatment responses in multiple myeloma

A multicenter study led by researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine shows how interactions between tumor cells and immune components of the microenvironment can impact treatment responses and outcomes in patients newly diagnosed with multiple myeloma who undergo combination treatments that include targeted immunotherapy.

9 Nov 2023

Study compiles the most comprehensive list of genetic variants associated with prostate cancer risk

A globe-spanning scientific team has compiled the most comprehensive list of genetic variants associated with prostate cancer risk - 451 in all - through a whole-genome analysis that ranks as the largest and most diverse investigation into prostate cancer genetics yet.

9 Nov 2023

Cannabis use alters DNA methylation, with implications beyond smoking effects

A large-scale meta-analysis in Molecular Psychiatry reveals that lifetime cannabis use is associated with DNA methylation changes in peripheral blood, which could have implications for understanding the long-term health effects of cannabis consumption.

8 Nov 2023

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Scientists at deCODE genetics, a subsidiary of Amgen, have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan.

8 Nov 2023

Gamma delta T cells engineered to be more potent and long-lasting against cancer

UCLA scientists have developed a new method to engineer more powerful immune cells that can potentially be used for "off-the-shelf" cell therapy to treat challenging cancers.

8 Nov 2023

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation that leads to pain, joint damage, and disability, which affects approximately 18 million people worldwide.

8 Nov 2023

Scientists unravel the mystery of how cells keep glutathione levels in check

If a delivery person leaves a package on your front step without pinging you, you likely won't know it's there.

8 Nov 2023

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Concurrent sequencing of DNA and RNA to detect the predisposition to hereditary cancer.

8 Nov 2023

Pharmacogenomics holds promise for personalized dementia therapies

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Genetics News and Research

Latest Genetics News and Research

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Study shows environment's pivotal role in healthy aging and disease prevention

"Christchurch mutation" can block detrimental effects of Alzheimer’s risk factor

Single injection of new medication effectively eliminates Lp(a) for nearly one year

Multi-ancestry study reveals 187 new genetic risk factors for prostate cancer

UCI researchers discover gene critical for muscle repair

Preclinical research points to a promising new treatment option for pancreatic cancer patients

New research aims to decipher how animals discard half their genes

Tumor-immune interactions predict treatment responses in multiple myeloma

Study compiles the most comprehensive list of genetic variants associated with prostate cancer risk

Cannabis use alters DNA methylation, with implications beyond smoking effects

Study finds 4% of Icelanders to carry an actionable genotype associated with shortened lifespan

Gamma delta T cells engineered to be more potent and long-lasting against cancer

Study sheds new light on the variety of cellular causes of rheumatoid arthritis

Scientists unravel the mystery of how cells keep glutathione levels in check

Can adding RNA sequencing to germline genetic testing improve accuracy and clinical sensitivity over time compared to DNA sequencing alone?

Pharmacogenomics holds promise for personalized dementia therapies

Targeting MYC-SPT5 interaction could lead to novel cancer therapies

Study provides insights into the epidemiology and genetics of clonal hematopoiesis

To what extent can genetic variations explain the associations between screen time and psychiatric problems in children?

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