Heart Disease News and Research

Latest Heart Disease News and Research

Low-calorie sweeteners play an important role for healthy, active people

The International Sweeteners Association (ISA) draws attention to a growing number of experts supporting the message that low calorie sweeteners play an important role for healthy, active people. Used in more than 6,000 products around the world, low calorie sweeteners can significantly reduce the energy density of foods and beverages when used as a substitute for sugar.

23 Jul 2012

Bayer, Onyx and Astellas announce results from Tarceva plus Nexavar Phase 3 trial on HCC

Bayer HealthCare Pharmaceuticals, Onyx Pharmaceuticals, Inc., and Astellas Pharma Inc. today announced that a Phase 3 trial evaluating the efficacy and safety of the addition of Tarceva (erlotinib) tablets to Nexavar (sorafenib) tablets did not improve overall survival for patients with unresectable hepatocellular carcinoma (HCC) vs. Nexavar alone.

23 Jul 2012

Recent guidelines that recommend cholesterol tests for children fail to weigh health benefits

Recent guidelines recommending cholesterol tests for children fail to weigh health benefits against potential harms and costs, according to a new commentary authored by three physician-researchers at UCSF.

23 Jul 2012

All adult patients with HIV should be offered ART: International Antiviral Society-USA panel

Included in the 2012 International Antiviral Society-USA panel recommendations for human immunodeficiency virus (HIV) patient care is that all adult patients, regardless of CD4 cell count, should be offered antiretroviral therapy (ART), according to an article in the July 25 issue of JAMA, a theme issue on HIV/AIDS.

23 Jul 2012

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

The elevated risk of cardiovascular disease seen in patients infected with HIV appears to be associated with increased inflammation within the arteries, according to a study that will appear in a special issue of JAMA published in conjunction with the International AIDS Conference.

23 Jul 2012

As AIDS conference opens, health panel urges treatment of all HIV infections

An international health panel has recommended for the first time that all HIV patients be treated with antiretroviral drugs, even when the virus's impact on their immune system is shown to be small. The nonprofit International Antiviral Society-USA cited new evidence that untreated infection with the human immunodeficiency virus that causes AIDS can also lead to a range of other conditions, including cardiovascular disease and kidney disease.

23 Jul 2012

Researchers turn inanimate silicone and living cardiac muscle cells into a jellyfish

Using recent advances in marine biomechanics, materials science, and tissue engineering, a team of researchers at Harvard University and the California Institute of Technology (Caltech) have turned inanimate silicone and living cardiac muscle cells into a freely swimming "jellyfish."

23 Jul 2012

Kyprolis for multiple myeloma receives FDA approval under accelerated approval program

The U.S. Food and Drug Administration today approved Kyprolis (carfilzomib) to treat patients with multiple myeloma who have received at least two prior therapies, including treatment with Velcade (bortezomib) and an immunomodulatory therapy. A form of blood cancer that arises from plasma cells, multiple myeloma usually grows in bone marrow, the soft, spongy tissue found inside most bones.

21 Jul 2012

State roundup: Texas Medicaid fraud probes use controversial tool

When it comes to finding cost savings in the state's unwieldy Medicaid program, the Health and Human Services Commission's Office of Inspector General gets high marks. … But OIG's dollar-recovery strategy -- which includes an increased reliance on a rule that allows investigators to freeze financing for any health provider accused of overbilling -- has enraged doctors, dentists and other providers who treat Medicaid patients.

21 Jul 2012

Study identifies genetic markers that influence protein involved in regulating oestrogen, testosterone levels

A research study led by the Peninsula College of Medicine and Dentistry, University of Exeter, and Boston University School of Medicine, in collaboration with a global consortium, has identified genetic markers that influence a protein involved in regulating oestrogen and testosterone levels in the bloodstream.

21 Jul 2012

Training EMS to interpret ECGs can expedite treatment for severe heart attacks

A new program that trains emergency medical service technicians (EMS) to read electrocardiograms so that they can evaluate patients with chest pain, and expedite treatment for the severe heart condition known as ST-segment elevation myocardial infarction (STEMI), a serious form of heart attack, has excellent results and should become the standard of care, according to two studies published in the current issue of the Canadian Journal of Cardiology.

21 Jul 2012

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

Ligand Pharmaceuticals Incorporated today announced that its licensee, Onyx Pharmaceuticals, received accelerated approval from the U.S. Food and Drug Administration (FDA) for Kyprolis (carfilzomib) for Injection, a proteasome inhibitor indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

Research roundup: Gastric bypass costs, paying for psychotherapy

Health Expenditures Among High-Risk Patients After Gastric Bypass and Matched Controls -- A few studies have shown that bariatric surgery can help reduce health care spending by obese patients, particularly those with conditions such as diabetes. This latest study looked at 847 patients who received bariatric surgery through the Veterans Affairs medical system. Inpatient and outpatient spending both before and after surgery were compared to 847 obese patients who did not have the operation.

21 Jul 2012

Pfizer receives positive opinion from EMA CHMP for crizotinib to treat ALK-positive NSCLC

Pfizer announced today that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has adopted a positive opinion recommending that crizotinib be granted conditional marketing authorization in the European Union (EU), for the treatment of adults with previously treated anaplastic lymphoma kinase (ALK)-positive advanced non-small cell lung cancer (NSCLC).

21 Jul 2012

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

Onyx Pharmaceuticals, Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted accelerated approval of Kyprolis (carfilzomib) for Injection, a proteasome inhibitor, indicated for the treatment of patients with multiple myeloma who have received at least two prior therapies, including bortezomib and an immunomodulatory agent, and have demonstrated disease progression on or within 60 days of completion of the last therapy.

21 Jul 2012

Regeneron, Sanofi initiate enrollment in SAR236553/REGN727 Phase 3 program

Sanofi and Regeneron Pharmaceuticals, Inc. announced today that several trials within ODYSSEY, the Phase 3 clinical program of SAR236553/REGN727, have initiated patient enrollment.

21 Jul 2012

Scientists uncover how internal mechanisms in nerve cells wire the brain

Scientists at the University of Manchester have uncovered how the internal mechanisms in nerve cells wire the brain. The findings open up new avenues in the investigation of neurodegenerative diseases by analysing the cellular processes underlying these conditions.

21 Jul 2012

Study identifies genetic markers that influence sex hormone-binding globulin

A research study led by Boston University School of Medicine (BUSM) and the University of Exeter in the United Kingdom, in collaboration with a global consortium, has identified genetic markers that influence a protein involved in regulating estrogen and testosterone levels in the bloodstream.

21 Jul 2012

Placenta-derived endothelial colony-forming cells are more vasculogenic: Study

A study comparing whether endothelial colony-forming cells (ECFCs) derived from human placenta or those derived from human umbilical cord blood are more proliferative and better for forming new blood vessels has found that ECFCs derived from human placenta are more vasculogenic.

20 Jul 2012

Phosphate binders may cause unexpected harm to blood vessels in patients with CKD

Drugs commonly prescribed to patients with chronic kidney disease (CKD) may not be as strongly effective as once thought, and may cause unexpected harm to blood vessels, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

20 Jul 2012

Heart Disease News and Research

Latest Heart Disease News and Research

Low-calorie sweeteners play an important role for healthy, active people

Bayer, Onyx and Astellas announce results from Tarceva plus Nexavar Phase 3 trial on HCC

Recent guidelines that recommend cholesterol tests for children fail to weigh health benefits

All adult patients with HIV should be offered ART: International Antiviral Society-USA panel

Targeting monocyte activation may reduce arterial inflammation in HIV-infected patients

As AIDS conference opens, health panel urges treatment of all HIV infections

Researchers turn inanimate silicone and living cardiac muscle cells into a jellyfish

Kyprolis for multiple myeloma receives FDA approval under accelerated approval program

State roundup: Texas Medicaid fraud probes use controversial tool

Study identifies genetic markers that influence protein involved in regulating oestrogen, testosterone levels

Training EMS to interpret ECGs can expedite treatment for severe heart attacks

FDA grants accelerated approval for Kyprolis to treat multiple myeloma

Research roundup: Gastric bypass costs, paying for psychotherapy

Pfizer receives positive opinion from EMA CHMP for crizotinib to treat ALK-positive NSCLC

FDA grants accelerated approval to Onyx's Kyprolis for treatment of multiple myeloma

Regeneron, Sanofi initiate enrollment in SAR236553/REGN727 Phase 3 program

Scientists uncover how internal mechanisms in nerve cells wire the brain

Study identifies genetic markers that influence sex hormone-binding globulin

Placenta-derived endothelial colony-forming cells are more vasculogenic: Study

Phosphate binders may cause unexpected harm to blood vessels in patients with CKD

Industry Focus eBook - Medical device (1st edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Heart Disease News and Research

Latest Heart Disease News and Research

Industry Focus eBook - Medical device (1st edition) eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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