Immunology News and Research

Latest Immunology News and Research

Phase 3 study finds inebilizumab effective for immunoglobulin G4–related disease

An international, phase 3 clinical trial led by investigators at Mass General Brigham could improve the treatment of a rare disease that can cause debilitating symptoms.

14 Nov 2024

Leveraging genetic variations for more effective cancer therapies

By exploiting the genetic variation in cancer cells, an already approved cancer drug demonstrated enhanced effects against cancer cells in specific patient groups.

14 Nov 2024

Study finds weakness in drug-resistant tuberculosis pathogens

A University of Otago-led study has found highly vulnerable weakness in drug-resistant Mycobacterium tuberculosis, offering a new way to kill them.

13 Nov 2024

Georgia Tech researchers create lab-grown models of human immune systems

To better understand why some cancer patients struggle to fight off infections, Georgia Tech researchers have created tiny lab-grown models of human immune systems.

12 Nov 2024

New approach reinvigorates exhausted T cells to improve tumor control

As cancer cells grow, they pump out metabolic byproducts such as lactic acid into the tumor microenvironment. Exhausted T cells - which have lost their cancer-fighting oomph - consume this lactic acid, which further saps their energy, according to new research from the University of Pittsburgh and UPMC Hillman Cancer Center.

8 Nov 2024

MD Anderson launches new institute for advancing cell therapy

The University of Texas MD Anderson Cancer Center today announced the launch of its Institute for Cell Therapy Discovery & Innovation, which will build upon longstanding MD Anderson clinical and research expertise to lead the world in developing and advancing impactful cell therapies for patients in need.

8 Nov 2024

Researchers uncover metabolic blockade that impedes cancer treatment response

The immune system is a major target for cancer treatments. Immune checkpoint inhibitors and CAR-T cell therapy can dramatically improve outcomes for many cancers. But for about 70% of patients, these therapies don't work.

8 Nov 2024

SARS-CoV-2 hijacks host proteins to escape immune clearance

Researchers at the Medical University of Vienna and the Medical University of Innsbruck discovered that SARS-CoV-2 hijacks three important host proteins that dampen the activity of the complement system, a key component of early antiviral immunity.

8 Nov 2024

Preeclampsia and COVID-19 share pathophysiological similarities in pregnant women

During the COVID-19 pandemic, above all before vaccines were available, an alarm was sounded regarding a possible correlation between severe cases of COVID-19 in pregnant women and preeclampsia, a condition characterized by high blood pressure (hypertension) in the expectant mother and high levels of protein in her urine (proteinuria). It can entail dangerous complications for mother and baby.

7 Nov 2024

Study links nasal autoantibodies to COVID-19 severity prediction

A wide variety of COVID-19 symptoms exist, ranging from mild to severe, and while current strains of the virus generally cause milder symptoms, those with co-morbidities are still at an exponentially greater risk of severe disease.

6 Nov 2024

Researchers uncover immune mechanism behind myocarditis from cancer immunotherapy

Some patients being treated with immune checkpoint inhibitors, a type of cancer immunotherapy, develop a dangerous form of heart inflammation called myocarditis.

6 Nov 2024

WHO report highlights surge in TB cases and deaths in 2023

The highest number of tuberculosis (TB) cases since global monitoring began were recorded in 2023, according to a report published by the World Health Organization (WHO).

6 Nov 2024

Exploring the circadian influence of immune cells on metabolic health and fat storage

Recent research reveals that the immune system interacts with the body's internal clock, influencing both fat storage and temperature regulation. These insights carry substantial implications for individuals with irregular work, eating, or sleep patterns driven by the demands of modern life.

6 Nov 2024

Researchers awarded Synergy Grant to target tumor vessels and boost immunotherapy

Targeting and customizing blood vessels in tumors to increase T cell infiltration and maintain their function may represent the next breakthrough in cancer therapy.

5 Nov 2024

Combination therapy shows promising results in treating stage 3 melanoma

Pre-surgery treatment with the novel drug vidutolimod and the PD-1 checkpoint inhibitor nivolumab led to tumor control in 55% of patients with stage 3 cutaneous melanoma, according to the results of a single-arm phase 2 clinical trial led by the University of Pittsburgh, UPMC Hillman Cancer Center and the National Cancer Institute (NCI).

1 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

Brain actively engages with immune system to maintain health

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue.

1 Nov 2024

New insights into cardiac defects in Myotonic Dystrophy Type 1

People with Myotonic Dystrophy Type 1 (DM1), the most common adult-onset form of muscular dystrophy, progressively lose muscle mass and strength in their lower legs, hands, neck and face.

29 Oct 2024

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

In this interview, conducted at SfN 2024 in Chicago, News Medical speaks with Joel Svensson and Carolyn Marks of Atlas Antibodies, about their new launch, the MolBoolean™, as well as how conferences like SfN are helping shape the future of neuroscience research.

From Atlas Antibodies AB 29 Oct 2024

Genetic marker could revolutionize neonatal sepsis diagnosis

A genetic signature in newborns can predict neonatal sepsis before symptoms even start to show, according to a new study.

29 Oct 2024

Immunology News and Research

Latest Immunology News and Research

Phase 3 study finds inebilizumab effective for immunoglobulin G4–related disease

Leveraging genetic variations for more effective cancer therapies

Study finds weakness in drug-resistant tuberculosis pathogens

Georgia Tech researchers create lab-grown models of human immune systems

New approach reinvigorates exhausted T cells to improve tumor control

MD Anderson launches new institute for advancing cell therapy

Researchers uncover metabolic blockade that impedes cancer treatment response

SARS-CoV-2 hijacks host proteins to escape immune clearance

Preeclampsia and COVID-19 share pathophysiological similarities in pregnant women

Study links nasal autoantibodies to COVID-19 severity prediction

Researchers uncover immune mechanism behind myocarditis from cancer immunotherapy

WHO report highlights surge in TB cases and deaths in 2023

Exploring the circadian influence of immune cells on metabolic health and fat storage

Researchers awarded Synergy Grant to target tumor vessels and boost immunotherapy

Combination therapy shows promising results in treating stage 3 melanoma

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Brain actively engages with immune system to maintain health

New insights into cardiac defects in Myotonic Dystrophy Type 1

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

Genetic marker could revolutionize neonatal sepsis diagnosis

eBook: Cell-based technologies in drug discovery and Immunotherapy eBook

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Extending the reach of Amperia™

Modular cleanrooms: Enhancing flexibility and compliance