Immunotherapy News and Research

Latest Immunotherapy News and Research

Moffitt researchers shed light on how CAR T cells function mechanistically

The scientific community has made great strides over the past decade in the development of a new class of cancer therapy called immunotherapy, a treatment that activates a patient's own immune system to target cancer cells.

15 Feb 2019

Blood-based liquid biopsies can accurately track cancer treatment responses

Results of two clinical studies have added to evidence that blood-based liquid biopsies can accurately track lung cancer treatment responses by measuring circulating tumor DNA (ctDNA) during immunotherapy and related treatments.

14 Feb 2019

Sleep could be the best medicine to fight off an infection

Sleep has been underrated as the best medicine to fight off disease say researchers working on a new study. The study titled, “Gαs-Coupled Receptor Signaling and Sleep Regulate Integrin Activation of Human Antigen-Specific T Cells,” was published this week in the Journal of Experimental Medicine.

14 Feb 2019

Comparison of cancer genes across species helps prioritize targets for new cancer therapies

Cancer genes in mucosal melanoma, a rare and poorly understood subtype of melanoma, have been compared in humans, dogs and horses for the first time by scientists at the Wellcome Sanger Institute and their collaborators.

12 Feb 2019

Inhibiting tuberculosis-induced cell death with immunotherapy

Tuberculosis treatment still entails the intake several antibiotics over a period of many months and is torturous for many patients. The pathogen's increasing multidrug resistance additionally complicates this lengthy treatment, and side effects frequently lead to a discontinuation of treatment and high mortality rates.

12 Feb 2019

Immunotherapy drug can be effective in treating patients with recurrent brain tumors

A UCLA-led study suggests that for people with recurrent glioblastoma, administering an immunotherapy drug before surgery is more effective than using the drug afterward.

11 Feb 2019

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

The first study of the immunotherapy drug pembrolizumab as the initial treatment for patients with a rare but aggressive form of skin cancer known as Merkel cell carcinoma reports better responses and longer survival than expected with conventional chemotherapy.

11 Feb 2019

Research finds new potential targets for treatment of pancreatic cancer

The first study in the world to take a detailed look at scar tissue in human pancreatic cancer has revealed a range of different scar tissue types that could help clinicians predict which patients will respond best to particular treatments.

11 Feb 2019

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Around a glioblastoma, a very aggressive brain tumor, cells of the human immune system start helping the tumor instead of attacking it. To do research on what happens in the interaction of these cells, scientists of the University of Twente now created a 3D-bioprinted mini model of the brain.

11 Feb 2019

Caltech scientists develop new methods for rapidly determining T cell targets

The human body's immune system is like a vast team of special agents. Certain cells called T cells each individually specialize in recognizing a particular intruder, such as the influenza virus or salmonella.

8 Feb 2019

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

A multi-center phase II clinical trial investigating pembrolizumab as a first-line and programmed cell death-1 therapy in patients with advanced Merkel cell carcinoma reports lasting tumor control, generally manageable side effects and improved overall survival.

8 Feb 2019

Simulation model to find the most optimal cancer treatment

In ten years, computers will be able to propose the most suitable cancer treatment for you. The idea is to simulate how all possible combinations of existing cancer treatments will work on your particular tumor.

6 Feb 2019

Drug cocktail may help combat breast cancer

MYC, a gene with high cancer-initiating potential, is overexpressed in over 40% of breast cancers. While MYC programs breast cancer cells to build more macromolecules (anabolic metabolism) it also creates a metabolic vulnerability by making them more sensitive to a type of cell death known as apoptosis.

6 Feb 2019

First precision medicine trial in lung cancer expands to include more patients

The Lung Cancer Master Protocol, the first precision medicine trial in lung cancer supported by the National Cancer Institute, part of the National Institutes of Health, is undergoing a major expansion to include patients with all non-small cell lung cancers -- which make up about 85 percent of all lung cancer diagnoses in the U.S.

29 Jan 2019

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

A Massachusetts General Hospital (MGH) research team has found that the overgrowth of connective called fibrosis may block the effectiveness of immunotherapies against metastatic breast cancer.

29 Jan 2019

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

Stand Up To Cancer announced here today the creation of an $8 million Dream Team of top scientists focused on finding therapies for T-cell lymphoma, a rare cancer of the blood and immune system, using chimeric antigen receptors (CARs) to trigger the immune system to attack and destroy cancerous cells.

29 Jan 2019

Immunotherapy News and Research

Latest Immunotherapy News and Research

Moffitt researchers shed light on how CAR T cells function mechanistically

Blood-based liquid biopsies can accurately track cancer treatment responses

Sleep could be the best medicine to fight off an infection

Comparison of cancer genes across species helps prioritize targets for new cancer therapies

Inhibiting tuberculosis-induced cell death with immunotherapy

Immunotherapy drug can be effective in treating patients with recurrent brain tumors

Immunotherapy may be better than chemotherapy for Merkel cell carcinoma

Research finds new potential targets for treatment of pancreatic cancer

Scientists create 3D-bioprinted brain model to study interaction with immune cells

Caltech scientists develop new methods for rapidly determining T cell targets

Immunotherapy drug found to be effective in patients with advanced Merkel cell carcinoma

Simulation model to find the most optimal cancer treatment

Drug cocktail may help combat breast cancer

First precision medicine trial in lung cancer expands to include more patients

Fibrosis-targeting drugs may benefit patients with late-stage, metastatic breast cancer

Stand Up To Cancer creates Dream Team focused on finding therapies for T-cell lymphoma

New precision medicine treatment for bone cancer in dogs opens door for human clinical trials

Genetically modified chickens could soon lay eggs containing certain medications

GW researchers engineer nanoimmunotherapy to treat cancer

Nine early career scientists named 2019 recipients of the Damon Runyon-Rachleff Innovation Award

Event guide: 7th Allogeneic Cell Therapies Summit eBook

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Immunotherapy News and Research

Latest Immunotherapy News and Research

Event guide: 7th Allogeneic Cell Therapies Summit eBook

The Proteoform Puzzle: Unlocking the Next Frontier

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

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