Immunotherapy News and Research

Latest Immunotherapy News and Research

New, potential therapy can disrupt myeloid cells that promote tumor growth

Cancerous tumors trick myeloid cells, an important part of the immune system, into perceiving them as a damaged part of the body; the tumors actually put myeloid cells to work helping them grow and metastasize (spread).

7 Jan 2019

Melanoma cells put to sleep by T cells improving outcomes, find researchers

Australian researchers have found that special immune cells of the body not only protect us from the invading bacteria, viruses and microbes but also play a role in reducing the aggressiveness of the melanoma cells.

1 Jan 2019

Scientists move one step closer towards treatment for low-grade gliomas with SYNODOS

Treatment for low-grade gliomas in patients living with neurofibromatosis type 1 are now one step closer thanks to recent research discoveries initiated and funded by the Children's Tumor Foundation.

28 Dec 2018

CWRU researcher receives nearly $1 million to study drug resistance mechanisms in prostate cancer

Sanjay Gupta, PhD, of Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center will receive $962,000 over three years to investigate drug resistance mechanisms in prostate cancer.

24 Dec 2018

New bacteria-based drug delivery system could radically expand cancer treatment options

An interdisciplinary team of three Virginia Tech faculty members affiliated with the Macromolecules Innovation Institute has created a drug delivery system that could radically expand cancer treatment options.

21 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

FSU researchers discover how breast cancer evades immune system detection

Recent breakthroughs in immunotherapy are making a huge difference in treating some forms of cancer, especially metastatic cancer. But breast cancer has proven a tricky foe for this new therapy, and an interdisciplinary team of FSU researchers is now a little bit closer to figuring out why.

18 Dec 2018

Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice

Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.

18 Dec 2018

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Due to their powerful tumor-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) effect even against dividing healthy cells.

18 Dec 2018

New findings could help develop new immunotherapies against cancer

NK cells, or natural killer cells, play an important role in the body's defences against cancer and various infections.

14 Dec 2018

World's largest AI-powered medical research network launched by OWKIN

OWKIN today announced the world's largest AI-powered medical research network. The OWKIN Loop Network is comprised of 44 prestigious hospitals and research institutions across the US and Europe, including Cleveland Clinic and Mount Sinai.

13 Dec 2018

Nobel Laureates lecture about immune checkpoint therapy for cancer treatment

The Nobel Lectures held by the laureates of the 2018 Nobel Prize in Physiology or Medicine saw Aula Medica at Karolinska Institutet filled to the brink. In addition to 1,000 audience members in the auditorium, people around the world were able to watch the live broadcast when James P. Allison and Tasuku Honjo talked about their research, the results of which have led to the ground-breaking immune checkpoint therapy for cancer treatment.

12 Dec 2018

The EORTC Brain Tumor Group and Protagen AG collaborate to study immuno-competence of long-term glioblastoma survivors

The European Organisation for Research and Treatment of Cancer Brain Tumor Group and Protagen AG today announced a collaboration to utilize Protagen’s Cancer Immunotherapy Array to identify autoantibody biomarkers that investigate the immunological profile and immuno-competence of long-term Glioblastoma survivors.

12 Dec 2018

Slow-growing type of glioma may be vulnerable to immunotherapy, suggests study

Immunotherapy has proved effective in treating a number of cancers, but brain tumors have remained stubbornly resistant.

11 Dec 2018

Lund University researchers succeed in obtaining dendritic cells by direct reprogramming

For the first time, a research team at Lund University in Sweden has successfully reprogrammed mouse and human skin cells into immune cells called dendritic cells.

9 Dec 2018

VCU researchers test vaccine against opioid abuse

Virginia Commonwealth University researchers are testing a vaccine against opioid abuse developed by the Scripps Research Institute in California. The vaccine is meant to block the effects of heroin and fentanyl in patients with opioid use disorder.

7 Dec 2018

New technology for profiling genetic makeup of myeloma tumor cells developed

Cancer arises when cells lose control. Deciphering the "blueprint" of cancer cells - outlining how cancer cells hijack specific pathways for uncontrolled proliferation - will lead to more efficient ways to fight it.

7 Dec 2018

Study sheds new light on microtubule binding proteins and microtubule dynamics

When bacteria or viruses enter the body, proteins on their surfaces are recognized and processed to activate T cells, white blood cells with critical roles in fighting infections.

6 Dec 2018

Researchers aim to demystify bladder immunity

We know that the bladder is a poorly understood organ, critical for storing metabolic waste. What we don’t know is how this unique environment impacts bladder immunity to common diseases such as urinary tract infections and bladder cancer.

6 Dec 2018

New approach turns B cells into factories that secrete sacs containing microRNAs

Cancer immunotherapy -- efforts to better arm a patient's own immune system to attack tumors -- has shown great potential for treating some cancers. Yet immunotherapy doesn't work for everyone, and some types of treatment can cause serious side effects.

5 Dec 2018