Immunotherapy News and Research

Latest Immunotherapy News and Research

Nasal vaccine may suppress peanut allergy in mice, study shows

A vaccine may successfully turn off peanut allergy in mice, a new study shows.Just three monthly doses of a nasal vaccine protected the mice from allergic reactions upon exposure to peanut, according to research from the Mary H. Weiser Food Allergy Center at the University of Michigan.

11 Apr 2018

Finding new drug target for common form of lung cancer

Research by Rutgers Cancer Institute of New Jersey investigators has identified novel functions of the superoxide dismutase 1 (SOD1) enzyme providing support that it could serve as a therapeutic target in the most common type of lung cancer.

10 Apr 2018

New comprehensive analysis of breast and gynecological cancers

A large amount of information has been gathered by researchers from University of Texas MD Anderson Cancer Center who were studying the molecular features of tumors and their subtypes. They were working on breast and four types of gynaecological cancers.

6 Apr 2018

Combined treatment prolongs survival in mouse models of malignant mesothelioma

Combined treatment with two cancer immunotherapy drugs - one a novel immune modulator and one that focuses and activates the antitumor immune response - significantly prolonged survival in mouse models of the aggressive cancer malignant mesothelioma.

2 Apr 2018

The Human Microbiome – A New Potential Fingerprint in Forensic Evidence?

Professor Jack Gilbert gives an overview of the Burglary Microbiome Project, which he discussed at Pittcon 2018.

From Pittcon 29 Mar 2018

Two immunotherapies used together for the first time to fight against solid tumors

Two immunotherapies - one that enables the T-cells a patient already has to better attack a tumor and another that can produce an independent and vigorous immune response - are being given together for the first time to help more patients wage a stronger war on a wide range of solid tumors, researchers say.

26 Mar 2018

Gut microbiome may promote pancreatic cancer by inducing immune suppression

Bacterial load was significantly higher in pancreatic tumor samples from patients with pancreatic ductal adenocarcinoma compared with pancreatic tissue from normal individuals, and in studies using mice, eliminating certain "bad" bacteria slowed the growth of pancreatic cancer, reversed immune suppression, and upregulated the immune checkpoint protein PD1.

22 Mar 2018

Immunotherapy combination increases overall survival in people with kidney cancer, study shows

Treating people with advanced metastatic kidney cancer using a combination of the immunotherapy drugs nivolumab (Opdivo) and ipilimumab (Yervoy) significantly increased overall survival versus treatment with sunitinib (Sutent) alone, according to new findings from researchers at Memorial Sloan Kettering Cancer Center that were reported today in the New England Journal of Medicine.

22 Mar 2018

Targeting aberrantly active telomerase to treat therapy-resistant melanoma

A study conducted at The Wistar Institute in collaboration with The University of Texas Southwestern Medical Center has demonstrated the efficacy of targeting aberrantly active telomerase to treat therapy-resistant melanoma.

21 Mar 2018

Hydrogel may accelerate healing of diabetic ulcers

A hydrogel invented at Rice University that is adept at helping the body heal may also be particularly good at treating wounds related to diabetes.

20 Mar 2018

Many parents still hesitate to try early peanut introduction, survey finds

In January 2017 guidelines were released urging parents to begin early introduction of peanut-containing foods to reduce the risk of peanut allergy. A new study shows those who are aware of the guidelines are still hesitant to put them into place and not everyone has heard of them.

20 Mar 2018

American Gene Technologies receives second immuno-oncology patent

American Gene Technologies International Inc., a leading gene and cell therapy company, today announced receipt of a second immuno-oncology patent on the stimulation of gamma delta T cells for treating solid tumors in epithelial cancers.

20 Mar 2018

Treating metastatic breast cancer with immunotherapy

Breast cancer, in the stage with distant metastases, is an incurable disease with a 5 years survival rate of about 5-10%. Immunotherapy has recently improved survival in metastatic breast cancer patients with breast cancer harboring the expression of HER 2 receptor.

19 Mar 2018

YCC launches new Yale Center for Immuno-Oncology

Yale Cancer Center has launched the Yale Center for Immuno-Oncology. The new center will build on YCC's international leadership in immunobiology, cancer immunology, and development of novel cancer immunotherapies. It is a partnership between YCC and the department of Immunobiology at Yale University.

15 Mar 2018

UCLA-developed nanospears could make gene therapies safer, faster and more cost-effective

UCLA scientists have developed a new method that utilizes microscopic splinter-like structures called "nanospears" for the targeted delivery of biomolecules such as genes straight to patient cells. These magnetically guided nanostructures could enable gene therapies that are safer, faster and more cost-effective.

15 Mar 2018

Ludwig researchers extend potential for personalized immunotherapy to ovarian cancer, other tumors

A Ludwig Cancer Research study shows that ovarian cancer, which has proved resistant to currently available immunotherapies, could be susceptible to personalized immunotherapy.

15 Mar 2018

Novel oncolytic virus expressing BiTE molecule elicits T cell-mediated killing of tumor cells

In a research article published in EMBO Molecular Medicine, a group of scientists at the University of Oxford have described a new twist on cancer immunotherapy, combining two independent cell killing approaches in a single therapeutic with high potency and broad applicability.

13 Mar 2018

Slow-release injectable gel boosts toxicity of cancer-fighting immunotherapy drugs

An immunotherapy drug embedded in a slow-release hydrogel invented at Rice University in collaboration with the University of Texas Health Science Center at Houston appears to be highly effective at killing cancer cells.

7 Mar 2018

Preventing metabolic exhaustion in immune cells could enhance effects of immunotherapy

If you're an immune cell gearing up to fight cancer, you'd better eat your breakfast. The tumor microenvironment is a harsh place, and tumor cells are ready to wear you out.

6 Mar 2018

Gene-editing technology enhances T cell immunotherapies for treating cancer

Last year, the Food and Drug Administration approved the first cellular immunotherapies to treat cancer. These therapies involve collecting a patient's own immune cells -- called T cells -- and supercharging them to home in on and attack specific blood cancers, such as hard-to-treat acute lymphoblastic leukemia and non-Hodgkin lymphoma.

6 Mar 2018