Immunotherapy News and Research

Latest Immunotherapy News and Research

Compugen, Bayer sign collaboration and license agreement for antibody-based cancer immunotherapies

Compugen Ltd. announced today the signing of a collaboration and license agreement for the research, development, and commercialization of antibody-based therapeutics for cancer immunotherapy against two novel Compugen discovered immune checkpoint regulators.

5 Aug 2013

Scientists discover way to target immune system to shrink tumors in mice

St. Jude Children's Research Hospital scientists have discovered a way to target the immune system to shrink or eliminate tumors in mice without causing autoimmune problems. Researchers also found evidence that the same mechanism may operate in humans. The study was published today in the advance online edition of Nature.

5 Aug 2013

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized, or spread, to the patient's brain.

2 Aug 2013

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Cancer immunotherapy aims to recruit a patient’s immune system to recognize cancer as foreign and dangerous and to remove it from the body, as it would an infection.

1 Aug 2013

Report suggests venom immunotherapy can make sufferers less allergic to insect stings

If you think summer insects are done setting their sights on ruining your outdoor gathering, think again. August's hot and dry climate is the perfect breeding ground for insects, especially yellow jackets. And for the millions of Americans allergic to insect stings, these late summer bugs can be deadly.

1 Aug 2013

ImmunoCellular initiates ICT-121 phase I trial in patients with recurrent glioblastoma multiforme

ImmunoCellular Therapeutics, Ltd. today announced initiation of a phase I clinical trial of cancer vaccine ICT-121 as a potential treatment for patients with recurrent glioblastoma multiforme.

30 Jul 2013

Adaptimmune initiates Phase I/IIa open-label clinical trial in patients with ovarian cancer

Adaptimmune announced today that it has opened a Phase I/IIa, multiple-site, two-cohort, open-label clinical trial in ovarian cancer at Roswell Park Cancer Institute (RPCI) in Buffalo, N.Y., and City of Hope (COH) in Duarte, Calif.

26 Jul 2013

Inovio plans to advance synthetic hTERT cancer vaccine into clinical trials in 2014

Inovio Pharmaceuticals, Inc. announced today that in a preclinical study with two animal models, Inovio's hTERT (human telomerase reverse transcriptase) DNA cancer vaccine administered with Inovio's CELLECTRA adaptive electroporation delivery technology generated robust and broad immune responses, broke the immune system's tolerance to its self-antigens, induced T-cells with a tumor-killing function, and increased the rate of survival.

24 Jul 2013

Research team receives NCI grant to develop precision therapies that kill cancer cells

A research team headed by Fred Hutchinson Cancer Research Center scientists Christopher Kemp, Ph.D., and Carla Grandori, M.D., Ph.D., has received a $4 million grant from the National Cancer Institute to develop precision therapies that selectively kill cancer cells while sparing normal, healthy tissue.

24 Jul 2013

Genentech announces that Phase III CLL11 study meets primary endpoint

Genentech, a member of the Roche Group, today announced positive results from the Phase III CLL11 study. At a pre-planned interim analysis, an independent data monitoring committee determined that the study met its primary endpoint showing that GA101 plus chlorambucil helped people live significantly longer without their disease worsening (progression-free survival; PFS) compared to Rituxan (rituximab) plus chlorambucil.

24 Jul 2013

Study helps explain why some people contract bacterial super-infections

A recent study published in the July issue of the Journal of Immunology helps explain why some humans contract bacterial super-infections like pneumonia with influenza. The research was led by Le Bonheur Pediatrician-in-Chief Jon McCullers, MD - an infectious disease specialist who is also chair of the Department of Pediatrics for the University of Tennessee Health Science Center and adjunct faculty at St. Jude Children's Research Hospital.

23 Jul 2013

NF-κB protein complex may boost immune system to eliminate cancerous cells

Researchers at Moffitt Cancer Center and Tianjin Medical University Cancer Institute and Hospital in China have discovered a gene expression signature that may lead to new immune therapies for lung cancer patients.

23 Jul 2013

Celgene to discontinue treatment with REVLIMID in phase III ORIGIN trial

Celgene Corporation today announced that after consultation with the U.S. Food and Drug Administration Celgene will discontinue treatment with REVLIMID (lenalidomide) in the open-label, phase III ORIGIN trial, which enrolled 450 patients in over 100 sites in 26 countries.

18 Jul 2013

Kolltan signs research agreement with CHOP for novel therapeutic approaches for neuroblastoma

Kolltan Pharmaceuticals, Inc., a privately held biopharmaceutical company, today announced a license and research agreement with The Children's Hospital of Philadelphia to commence a collaboration with Yaël Mossé, M.D, an internationally recognized clinician and scientist for her work studying the causes and novel therapeutic approaches for the treatment of children diagnosed with neuroblastoma.

18 Jul 2013

Study brings new hope for patients with metastatic prostate cancer

A study of a new radiotherapeutic drug published this week in the New England Journal of Medicine brings fresh hope for a particular group of cancer patients that otherwise suffer and ultimately die from the disease -- those with prostate cancer that has spread to their bones and has failed to be controlled by hormone deprivation drugs.

18 Jul 2013

New class of WBCs in human lung and gut tissues play a critical role against fungal infections

Scientists at A*STAR's Singapore Immunology Network (SIgN) have discovered a new class of white blood cells in human lung and gut tissues that play a critical role as the first line of defence against harmful fungal and bacterial infections.

18 Jul 2013

Weill Cornell reports new findings from IVIG Phase 3 trial in Alzheimer's disease at AAIC 2013

Weill Cornell Medical College neurologist Dr. Norman Relkin reported new findings today from the Phase 3 clinical trial of IVIG (intravenous immunoglobulin) in mild to moderate Alzheimer's disease at the Alzheimer's Association International Conference in Boston, Mass.

16 Jul 2013

Seattle Children's leukemia patient has positive response to T-cell therapy

The first patient in a cellular immunotherapy Phase 1 cancer trial at Seattle Children's has had a positive response to T-cell therapy. The 23-year-old patient, Lynsie Conradi, from Bellingham, Wash. received the welcome news yesterday.

12 Jul 2013

Antibodies boost immune system to fight childhood cancer, shows study

Researchers in the Antibody and Vaccine Group have developed two monoclonal antibodies (mAbs) called anti-4-1BB and anti-CD40 and investigated a third called anti-CTLA-4. Each of these antibodies binds to a different target molecule in the immune system, potentially heightening the body's own immune response to cancer.

12 Jul 2013

Study highlights importance of doctors asking parents, children about asthma symptoms

The allergist's office might not be a child's favorite place to visit, but it is a place where they should be able to say how their asthma makes them feel. While children might rely on parents to tell their doctor about how they are feeling, according to a study released today, children should do most of the talking.

10 Jul 2013

Immunotherapy News and Research

Latest Immunotherapy News and Research

Compugen, Bayer sign collaboration and license agreement for antibody-based cancer immunotherapies

Scientists discover way to target immune system to shrink tumors in mice

UCLA researchers develop treatment approach for breast cancer metastasized to brain

Using the immune system to control cancer: an interview with Dr. Jedd Wolchok, MD, PhD, Ludwig Center at MSKCC

Report suggests venom immunotherapy can make sufferers less allergic to insect stings

ImmunoCellular initiates ICT-121 phase I trial in patients with recurrent glioblastoma multiforme

Adaptimmune initiates Phase I/IIa open-label clinical trial in patients with ovarian cancer

Inovio plans to advance synthetic hTERT cancer vaccine into clinical trials in 2014

Research team receives NCI grant to develop precision therapies that kill cancer cells

Genentech announces that Phase III CLL11 study meets primary endpoint

Study helps explain why some people contract bacterial super-infections

NF-κB protein complex may boost immune system to eliminate cancerous cells

Celgene to discontinue treatment with REVLIMID in phase III ORIGIN trial

Kolltan signs research agreement with CHOP for novel therapeutic approaches for neuroblastoma

Study brings new hope for patients with metastatic prostate cancer

New class of WBCs in human lung and gut tissues play a critical role against fungal infections

Weill Cornell reports new findings from IVIG Phase 3 trial in Alzheimer's disease at AAIC 2013

Seattle Children's leukemia patient has positive response to T-cell therapy

Antibodies boost immune system to fight childhood cancer, shows study

Study highlights importance of doctors asking parents, children about asthma symptoms

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

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