Immunotherapy News and Research

Latest Immunotherapy News and Research

International panel develops standardized definitions of immunotherapy side effects

An international panel of oncology and immunotherapy experts led by RCSI's Professor Jarushka Naidoo, has developed standardized definitions of the side effects of cancer immunotherapy to assist clinicians in treating patients.

5 Apr 2023

Novel immunotherapy-based approach for low-grade lymphomatoid granulomatosis improves patient survival

Results from a clinical trial conducted by researchers at the National Institutes of Health (NIH) show that people with low-grade lymphomatoid granulomatosis who are treated with interferon alfa-2b, a type of immunotherapy, can live for decades after diagnosis.

4 Apr 2023

Long-term pancreatic cancer survivors’ microbiomes have increased levels of specific bacteria

Even as pancreatic cancer treatments improve, only about 9% of patients survive past five years. Researchers have searched unsuccessfully to find genetic differences that explain why some patients survive long term and some do not and have now shifted their focus to the gut microbiome.

3 Apr 2023

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Researchers explored the correlation between autoimmunity and obesity.

3 Apr 2023

Transposable elements in various cancers could be used to harness novel immunotherapies

New research from Washington University School of Medicine in St. Louis suggests that transposable elements in various cancers potentially may be used to harness novel immunotherapies against tumors that don't typically respond to immune-based treatments. Shown is a 3D rendering of cancer cells.

31 Mar 2023

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

With the aid of a near $3.2 million National Cancer Institute grant (R01CA277599) recently awarded, investigators from the state's leading cancer program, Rutgers Cancer Institute of New Jersey,  and Georgetown University's Lombardi Comprehensive Cancer Center, both NCI-designated Comprehensive Cancer Centers, will work to close racial disparity gaps in cancer care delivery by examining a novel approach to genetic testing and care based on community-identified needs.

30 Mar 2023

Study shows how neutrophils play a key role in cancer immunotherapy success

Cancer immunotherapies that recruit a patient's own immune system to destroy tumors have transformed the treatment of many types of cancer. Yet these therapies do not elicit universally good treatment responses.

30 Mar 2023

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Immune checkpoint inhibitors (ICIs) are widely sought after for the treatment of different types of cancers. Unfortunately, only 20–30% patients with cancer respond to ICI treatment.

29 Mar 2023

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

An international group of researchers, led by Dr. José Ángel Martínez-Climent at the Cima University of Navarra, has created mouse avatars of patients with multiple myeloma to study and develop personalized treatments against this blood cancer, the second most frequent hematological cancer and incurable in most cases.

29 Mar 2023

Chemotherapy plus immunotherapy improves outcomes in patients with advanced endometrial cancer

Endometrial cancer, which makes up about 90% of uterine cancers, will be diagnosed in more than 65,000 people in the United States this year.

28 Mar 2023

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Cancer that has spread to areas like the lungs can apply the brakes to a natural pathway that should recruit killer T cells directly to where it has metastasized, scientists report.

28 Mar 2023

Combination treatment for advanced endometrial cancer significantly reduces disease growth

In a study published in the March 27, 2023, online edition of the New England Journal of Medicine, researchers at the University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health found the combination of immunotherapy (pembrolizumab) and chemotherapy in patients with advanced or recurrent/advanced endometrial cancer resulted in a significant reduction in disease growth when compared with chemotherapy alone.

27 Mar 2023

Enhancing the effectiveness of immunization against certain cancers

In addition to an antigen, many vaccines also contain substances, called adjuvants, which stimulate the immune system.

27 Mar 2023

Advanced surgical therapy proves to be effective for patients with uveal melanoma liver metastases

An advanced surgical therapy has proved considerably more efficacious than conventional treatments for patients with melanoma in the eye (uveal) that has spread to the liver, a University of Gothenburg study shows.

21 Mar 2023

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Cancer treatment routinely involves taking out lymph nodes near the tumor in case they contain metastatic cancer cells.

20 Mar 2023

Novel immunotherapeutic strategies to target the complex tumor immune microenvironment in head and neck cancer

A symposium aiming to provide a better understanding of the tumor microenvironment, immune tolerogenic niches at cancer initiation, and novel immunotherapeutic strategies in head and neck cancer patients was featured at the 52nd Annual Meeting & Exhibition of the AADOCR, held in conjunction with the 47th Annual Meeting of the CADR.

20 Mar 2023

Machine learning applications for the diagnosis, treatment and prognosis of cancer

Researchers review the application of machine learning in improving cancer diagnosis, treatment, and prognosis.

19 Mar 2023

Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery – until possibly now.

17 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

A new approach that delivers a "one-two punch" to help T cells attack solid tumors is the focus of a preclinical study by researchers from the Perelman School of Medicine at the University of Pennsylvania.

15 Mar 2023

Immunotherapy News and Research

Latest Immunotherapy News and Research

International panel develops standardized definitions of immunotherapy side effects

Novel immunotherapy-based approach for low-grade lymphomatoid granulomatosis improves patient survival

Long-term pancreatic cancer survivors’ microbiomes have increased levels of specific bacteria

Researcher hypothesizes that overnutrition could lead to loss of self-tolerance by impinging on immune regulation

Transposable elements in various cancers could be used to harness novel immunotherapies

$3.2 million grant aids in the study of genetic testing approach to close racial disparity gaps in cancer care

Study shows how neutrophils play a key role in cancer immunotherapy success

Diverse subset of T-cell clones plays a role in the antitumor effects of immune checkpoint inhibitors

Mouse avatars could help design more effective and personalized therapies for multiple myeloma

Chemotherapy plus immunotherapy improves outcomes in patients with advanced endometrial cancer

Newly found strategy used by metastasized tumors may explain why some promising immunotherapies fail

Combination treatment for advanced endometrial cancer significantly reduces disease growth

Enhancing the effectiveness of immunization against certain cancers

Advanced surgical therapy proves to be effective for patients with uveal melanoma liver metastases

Leaving lymph nodes intact until after immunotherapy could boost efficacy against solid tumors

Novel immunotherapeutic strategies to target the complex tumor immune microenvironment in head and neck cancer

Machine learning applications for the diagnosis, treatment and prognosis of cancer

Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Study focuses on new approach that delivers a "one-two punch" to help T cells attack solid tumors

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Immunotherapy News and Research

Latest Immunotherapy News and Research

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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