Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Obese patients undergoing colon surgery more likely to develop costly surgical-site infections

Obese patients undergoing colon surgery are 60 percent more likely to develop dangerous and costly surgical-site infections than their normal-weight counterparts, new Johns Hopkins research suggests.

17 May 2011

GSK, AstraZeneca and University of Manchester create new collaborative centre for inflammation research

The University of Manchester, GlaxoSmithKline and AstraZeneca announce today the creation of the Manchester Collaborative Centre for Inflammation Research, a unique collaboration to establish a world-leading translational centre for inflammatory diseases. The project starts out with an initial investment of -5M from each partner over a three year period.

From The University of Manchester 12 May 2011

Insight into probiotic bacteria can help improve intestinal disease treatments

The gut may need bacteria to provide a little bit of oxidative stress to stay healthy, new research suggests. Probiotic bacteria promote healing of the intestinal lining in mice by inducing the production of reactive oxygen species, researchers at Emory University School of Medicine have shown.

11 May 2011

AGA's cutting-edge research on GI disorders to be presented at DDW 2011

Clinicians, researchers and scientists from around the world will gather for Digestive Disease Week- 2011, the largest and most prestigious gastroenterology meeting, from May 7-10, 2011, at McCormick Place, Chicago, IL.

7 May 2011

FibroGen announces proof-of-principle for FG-4592 Phase 2 study in hemodialysis patients

FibroGen, Inc., today announced proof-of-principle for oral anemia therapy FG-4592, a hypoxia-inducible factor (HIF) prolyl hydroxylase inhibitor, in end-stage renal disease patients receiving hemodialysis.

4 May 2011

Santarus' budesonide MMX Phase III data in ulcerative colitis to be presented at DDW 2011

Santarus, Inc. today announced that the budesonide MMX Phase III clinical program will be featured in two oral presentations at the Digestive Disease Week Meeting being held at McCormick Place in Chicago on May 7-10, 2011.

3 May 2011

Scientists discover how immune cells recognize invading pathogens in the body

Scientists at Cedars-Sinai Medical Center have discovered how a molecular receptor on the surface of white blood cells identifies when invading fungi have established direct contact with the cell surface and pose an infectious threat.

30 Apr 2011

Antibiotics may serve as effective treatment for appendicitis than surgery

Antibiotics rather than surgery may be the better treatment for cases of appendicitis in which the appendix hasn't burst, according to a new study.

29 Apr 2011

Top-line results from Pfizer's tofacitinib Phase 3 studies in RA

Pfizer Inc. announced today top-line results from the ORAL Standard and ORAL Step Phase 3 studies of tofacitinib, an investigational, novel, oral JAK inhibitor.

29 Apr 2011

Researchers reveal how immune system distinguishes between beneficial and pathogenic organisms

The human gut is filled with 100 trillion symbiotic bacteria-ten times more microbial cells than our own cells-representing close to one thousand different species. "And yet, if you were to eat a piece of chicken with just a few Salmonella, your immune system would mount a potent inflammatory response," says Sarkis K. Mazmanian, assistant professor of biology at the California Institute of Technology (Caltech).

22 Apr 2011

IBD patients at greater risk of death if infected with Clostridium difficile

Patients admitted to hospital with inflammatory bowel disease (IBD) face a sixfold greater risk of death if they become infected with Clostridium difficile, a new study has found. The researchers say IBD patients should be screened on admission to protect them from serious illness.

20 Apr 2011

Chronic inflammation due to infection may lead to cancer

A new study shows how inflammation can help cause cancer. Chronic inflammation due to infection or to conditions such as chronic inflammatory bowel disease is associated with up to 25 percent of all cancers.

20 Apr 2011

Scientists develop new compound for multiple sclerosis treatment

Scientists from the Florida campus of The Scripps Research Institute have developed the first of a new class of highly selective compounds that effectively suppresses the severity of multiple sclerosis in animal models.

18 Apr 2011

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

Pfizer Inc. announced today top-line results from the ORAL Scan Phase 3 study of tofacitinib, formerly known as tasocitinib, an investigational, novel, oral JAK inhibitor.

15 Apr 2011

AJG publishes new review on Inflammatory Bowel Disease management

The American College of Gastroenterology published a new evidence-based systematic review on the management of Inflammatory Bowel Disease as a supplement to The American Journal of Gastroenterology for April 2011, a special issue entirely dedicated to IBD.

8 Apr 2011

Optimer study highlights economic burden of acute and recurrent CDI in hospital patients

Optimer Pharmaceuticals, Inc. announced today the presentation of information from insurance claims and survey databases highlighting the unmet need for targeted therapies to treat subpopulations at high risk of recurrence of Clostridium difficile infection.

4 Apr 2011

PUMA-mediated intestinal apoptosis contributes to ulcerative colitis in humans, mice

Ulcerative colitis is an inflammatory bowel disease thought to be related to aberrant activation of the immune system in the intestine. Recent research has also suggested that regulated cell death of the intestinal epithelial cells is a contributing factor to the pathogenesis.

2 Apr 2011

New discovery on IL-23 can lead to novel IBD treatments

A new discovery published in the April 2001 issue of Journal of Leukocyte Biology raises hope that new treatments for illnesses like Crohn's disease and ulcerative colitis are on the horizon.

1 Apr 2011

Inflammatory bowel disease in children - Delays in diagnosis common

Once a medical rarity in children, inflammatory bowel disease today is increasingly common in kids, but many of them may not be diagnosed in a timely manner, according to experts from the Pediatric Inflammatory Bowel Disease Center at Johns Hopkins Children’s Center.

28 Mar 2011

Researchers create new computational model to understand animal cell behavior

Biological systems, including cells, tissues and organs, can function properly only when their parts are working in harmony. These systems are often dauntingly complex: Inside a single cell, thousands of proteins interact with each other to determine how the cell will develop and respond to its environment.

24 Mar 2011

Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Obese patients undergoing colon surgery more likely to develop costly surgical-site infections

GSK, AstraZeneca and University of Manchester create new collaborative centre for inflammation research

Insight into probiotic bacteria can help improve intestinal disease treatments

AGA's cutting-edge research on GI disorders to be presented at DDW 2011

FibroGen announces proof-of-principle for FG-4592 Phase 2 study in hemodialysis patients

Santarus' budesonide MMX Phase III data in ulcerative colitis to be presented at DDW 2011

Scientists discover how immune cells recognize invading pathogens in the body

Antibiotics may serve as effective treatment for appendicitis than surgery

Top-line results from Pfizer's tofacitinib Phase 3 studies in RA

Researchers reveal how immune system distinguishes between beneficial and pathogenic organisms

IBD patients at greater risk of death if infected with Clostridium difficile

Chronic inflammation due to infection may lead to cancer

Scientists develop new compound for multiple sclerosis treatment

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

AJG publishes new review on Inflammatory Bowel Disease management

Optimer study highlights economic burden of acute and recurrent CDI in hospital patients

PUMA-mediated intestinal apoptosis contributes to ulcerative colitis in humans, mice

New discovery on IL-23 can lead to novel IBD treatments

Inflammatory bowel disease in children - Delays in diagnosis common

Researchers create new computational model to understand animal cell behavior

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Inflammatory Bowel Disease News and Research

Latest Inflammatory Bowel Disease News and Research

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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