Lupus News and Research

Latest Lupus News and Research

XTL signs agreement with Yeda to amend development milestones for lupus treatment

XTL Biopharmaceuticals Ltd., a clinical-stage biopharmaceutical company focused on the development and commercialization of pharmaceutical products for the treatment of unmet clinical needs with a focus on treatments for autoimmune diseases, today announced that it has reached agreement with Yeda Research and Development Company Ltd. to amend the development milestones in the License Agreement signed between the parties in January 2014 for the development of hCDR1 for the treatment of systemic lupus erythematosus (SLE).

13 Oct 2015

ImmunArray launches SLE-key Rule-Out test for lupus patients

Following a limited three-month trial period in which more than one hundred and fifty patients with lupus-like symptoms were tested for the difficult-to-diagnose disease, a new blood test for lupus is being rolled out nationally.

12 Oct 2015

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

Scientists have calculated more precise measurements of heritability--the influence of underlying genes--in nine autoimmune diseases that begin in childhood. The research may strengthen researchers' abilities to better predict a child's risk for associated autoimmune diseases.

9 Oct 2015

Phase II psoriasis study shows efficacy of Boehringer Ingelheim's BI 655066 over ustekinumab

New results from a Phase II head-to-head psoriasis study showed superior efficacy of Boehringer Ingelheim's investigational biologic compound BI 655066, over ustekinumab. After nine months, 69 percent of patients with moderate-to-severe plaque psoriasis maintained clear or almost clear skin (PASI 90) with BI 655066 in the higher dose group compared to 30 percent of patients on ustekinumab.

8 Oct 2015

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Mallinckrodt plc, a leading specialty biopharmaceutical company, today announced that data from a pilot study for its H.P. Acthar Gel (repository corticotropin injection) will be presented at the American College of Rheumatology 2015 Annual Meeting to be held November 7-11 in San Francisco.

8 Oct 2015

Study: Biomarkers in maternal blood may predict risk for adverse outcomes in pregnant women with SLE

Pregnant women with systemic lupus erythematosus (SLE), are at higher risk for adverse pregnancy outcomes, including preeclampsia, placental insufficiency, fetal death, miscarriages, and other complications.

29 Sep 2015

Experts to discuss research on lupus at world congress organized by MedUni Vienna

Lupus is an autoimmune disease with so many different symptoms that it is often difficult to diagnose and to treat. Despite huge medical advances over the last few years, lupus is incurable. Modern, individually tailored therapeutic approaches are aimed at helping sufferers. The world congress organized by MedUni Vienna brings experts from more than 80 countries together in Vienna from 2 to 6 September to discuss the latest research results and therapies.

1 Sep 2015

ACR commends FDA’s draft guidance requiring distinct names for biosimilars, biologic therapies

The American College of Rheumatology (ACR) today praised the Food and Drug Administration (FDA) for issuing draft guidance requiring separate and distinct names for biosimilars and biologic therapies.

28 Aug 2015

Brain scans may help predict patients' response to antipsychotic drug treatment

Investigators at The Feinstein Institute for Medical Research have discovered that brain scans can be used to predict patients' response to antipsychotic drug treatment. The findings are published online in the latest issue of The American Journal of Psychiatry.

28 Aug 2015

Study of genetic risk factors of IBD in African-Americans published in Gastroenterology journal

Researchers at the Johns Hopkins University School of Medicine, along with colleagues at Emory University and Cedars-Sinai, have published in the journal Gastroenterology the first major, in-depth analysis of genetic risk factors of inflammatory bowel disease in African-Americans.

26 Aug 2015

Janus collaborates with Roche to develop TLR inhibitor to address several autoimmune diseases

Janus Biotherapeutics today announced that they have entered into a collaboration with Roche for the development of a small molecule toll-like receptor (TLR) inhibitor with the potential to address several autoimmune diseases. TLRs are an important class of proteins that play a key role in the innate immune system.

20 Aug 2015

Hospira announces TGA approval of Inflectra (infliximab) for treatment of eight inflammatory conditions

Hospira today announced that Inflectra (infliximab), the first monoclonal antibody (mAb) biosimilar therapy, has been registered in Australia. This registration paves the way for the Federal Government to reduce the cost of some of the most expensive medicines on the Pharmaceutical Benefits Scheme (PBS).

20 Aug 2015

Allergan receives FDA approval to market 28 additional styles of Natrelle 410 silicone-filled breast implants

Allergan, plc. today announced that the company has received approval from the U.S. Food and Drug Administration to market 28 additional styles of Natrelle 410 silicone-filled breast implants, giving surgeons and patients more options to achieve desired outcomes.

6 Aug 2015

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Adults who are worried or terrified sometimes curl up into a fetal position. Likewise, adult cells that are injured, including genetic injury leading to cancer, initiate a process that was present during embryonic development.

4 Aug 2015

Inova Diagnostics announces FDA clearance for QUANTA Flash assays, QUANTA Flash Beta-2GP1 Domain1

Inova Diagnostics, a worldwide leader in autoimmune diagnostic reagents and systems for the clinical laboratory, announced today that it has received 510(k) clearance by the U.S. Food and Drug Administration on key QUANTA Flash assays for use with Inova Diagnostics' BIO-FLASH chemiluminescent analyzer for autoimmune testing.

20 Jul 2015

Emory University immunologists identify long-lived antibody-producing cells in bone marrow

Immunologists from Emory University have identified a distinct set of long-lived antibody-producing cells in the human bone marrow that function as an immune archive.

16 Jul 2015

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

Systemic lupus erythematosus (SLE) is an autoimmune disease that produces autoantibodies and subsequent immune reactions that can lead to a variety of symptoms, including inflammation of the kidneys, or nephritis. When researchers transplanted mesenchymal stem cells (MSCs) derived from human bone marrow into mice modeled with SLE, they found that inflammation was reduced and nephritis "attenuated."

15 Jul 2015

TSRI researchers awarded grant to study how environmental factors trigger autoimmune diseases

According to the U.S. Centers for Disease Control and Prevention, at least 1.5 million Americans suffer from rheumatoid arthritis and 322,000 have lupus, a chronic and potentially life-threatening disease that can damage skin, joints and organs.

10 Jul 2015

Bacterial biofilms play role in development of systemic lupus erythematosus

Lupus, multiple sclerosis, and type-1 diabetes are among more than a score of diseases in which the immune system attacks the body it was designed to defend. But just why the immune system begins its misdirected assault has remained a mystery.

7 Jul 2015

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

Mohamed Boutjdir, PhD, professor of medicine, cell biology, and physiology and pharmacology at SUNY Downstate Medical Center, has led a study with international collaborators identifying the mechanism by which patients with various autoimmune and connective tissue disorders may be at risk for life-threatening cardiac events if they take certain anti-histamine or anti-depressant medications.

7 Jul 2015

Lupus News and Research

Latest Lupus News and Research

XTL signs agreement with Yeda to amend development milestones for lupus treatment

ImmunArray launches SLE-key Rule-Out test for lupus patients

Scientists calculate precise measurements of heritability in nine pediatric-onset autoimmune diseases

Phase II psoriasis study shows efficacy of Boehringer Ingelheim's BI 655066 over ustekinumab

Clinical study data on Mallinckrodt's H.P. Acthar Gel to be presented at ACR 2015

Study: Biomarkers in maternal blood may predict risk for adverse outcomes in pregnant women with SLE

Experts to discuss research on lupus at world congress organized by MedUni Vienna

ACR commends FDA’s draft guidance requiring distinct names for biosimilars, biologic therapies

Brain scans may help predict patients' response to antipsychotic drug treatment

Study of genetic risk factors of IBD in African-Americans published in Gastroenterology journal

Janus collaborates with Roche to develop TLR inhibitor to address several autoimmune diseases

Hospira announces TGA approval of Inflectra (infliximab) for treatment of eight inflammatory conditions

Allergan receives FDA approval to market 28 additional styles of Natrelle 410 silicone-filled breast implants

Study demonstrates significance of EMT as potential therapeutic target for reversing kidney disease

Inova Diagnostics announces FDA clearance for QUANTA Flash assays, QUANTA Flash Beta-2GP1 Domain1

Emory University immunologists identify long-lived antibody-producing cells in bone marrow

Transplanted MSCs slow progression of lupus nephritis by suppressing Tfh cells in SLE animal model

TSRI researchers awarded grant to study how environmental factors trigger autoimmune diseases

Bacterial biofilms play role in development of systemic lupus erythematosus

Researchers identify link between autoimmune diseases, medications and Long QT syndrome

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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Lupus News and Research

Latest Lupus News and Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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