Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Overview

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Latest Lupus News and Research

Study explores how sex chromosomes and hormones influence immune responses

Study explores how sex chromosomes and hormones influence immune responses

Fusion proteins enable the creation of monoclonal antibodies

Fusion proteins enable the creation of monoclonal antibodies

Cedars-Sinai study shows rapid healing of heart damage with cell therapy

Cedars-Sinai study shows rapid healing of heart damage with cell therapy

Yale study unlocks potential of lupus-related antibody to target cold tumors

Yale study unlocks potential of lupus-related antibody to target cold tumors

Understanding the role of iron-dependent ferroptosis in immune suppression

Understanding the role of iron-dependent ferroptosis in immune suppression

Fighting cancer, inflammation and unlocking dementia diagnostics

Fighting cancer, inflammation and unlocking dementia diagnostics

Natural ingredient gluconolactone offers hope for targeted lupus therapy

Natural ingredient gluconolactone offers hope for targeted lupus therapy

Regulating cell acidity could transform autoimmune disease treatments

Regulating cell acidity could transform autoimmune disease treatments

Under Trump, Social Security resumes what it once called ‘clawback cruelty

Under Trump, Social Security resumes what it once called ‘clawback cruelty

Researchers discover why scleroderma affects women more than men

Researchers discover why scleroderma affects women more than men

Misdiagnosis of autoimmune diseases leads to long-term patient impact

Misdiagnosis of autoimmune diseases leads to long-term patient impact

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Epstein-Barr virus infection predisposes people to develop Crohn's disease

Corticosteroid use linked to higher risk of lupus pericarditis recurrence

Corticosteroid use linked to higher risk of lupus pericarditis recurrence

Machine learning algorithm decodes immune system’s hidden data for disease detection

Machine learning algorithm decodes immune system’s hidden data for disease detection

Study focuses on diagnostic delays experienced by people with epilepsy

Study focuses on diagnostic delays experienced by people with epilepsy

Granzyme K identified as key trigger of complement system in autoimmune diseases

Granzyme K identified as key trigger of complement system in autoimmune diseases

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Biomarker test can improve neonatal outcomes for preterm births

Biomarker test can improve neonatal outcomes for preterm births

Key information to consider before getting breast implants

Key information to consider before getting breast implants

Food safety tips to keep illness at bay

Food safety tips to keep illness at bay

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