Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Latest Lupus News and Research

Pharmacies are turning away immunocompromised patients seeking 4th covid shot

Pharmacies are turning away immunocompromised patients seeking 4th covid shot

New, more accurate tool to measure the progress of lupus in patients

New, more accurate tool to measure the progress of lupus in patients

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

New therapies for AIRDs can reduce the harmful side-effects caused by conventional treatments

Transplant recipients benefit from a COVID-19 vaccine booster

Transplant recipients benefit from a COVID-19 vaccine booster

SARS-CoV-2 infection can produce self-attacking autoantibodies

SARS-CoV-2 infection can produce self-attacking autoantibodies

11 exceptional recipients of the 2021 Lupus Innovation Award announced

11 exceptional recipients of the 2021 Lupus Innovation Award announced

Impact of mRNA-1273 vaccination during early pregnancy

Impact of mRNA-1273 vaccination during early pregnancy

UVA researchers uncover common link between lupus and macular degeneration

UVA researchers uncover common link between lupus and macular degeneration

Investigating the zoonotic adaptation and anthropozoonotic transmission of SARS-CoV-2

Investigating the zoonotic adaptation and anthropozoonotic transmission of SARS-CoV-2

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

The autoantibody profile in COVID-19 patients with MIS-C

The autoantibody profile in COVID-19 patients with MIS-C

Study looks at how lupus genetics intersects with COVID-19

Study looks at how lupus genetics intersects with COVID-19

Study finds persistent racial gaps in renal complications for children with juvenile lupus

Study finds persistent racial gaps in renal complications for children with juvenile lupus

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

Fetal heart rate monitoring is feasible, accurate for managing high-risk pregnancies

Black patients with systemic sclerosis may experience poorer outcomes more often than others

Black patients with systemic sclerosis may experience poorer outcomes more often than others

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

Study reassures the safety, immunogenicity of COVID-19 vaccines for patients with rheumatic diseases

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

New findings can help identify people at increased risk of hydroxychloroquine-related retinopathy

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Research reveals the microbial landscape of patients with systemic lupus erythematosus

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

Frequency domain optical imaging could reliably identify lupus arthritis and track disease progression

New research focuses on better understanding of lupus in Black women

New research focuses on better understanding of lupus in Black women