Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Lupus, also called systemic lupus erythematosus or SLE, is a disease that affects your immune system. Normally, your immune system fights infections caused by germs.

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Latest Lupus News and Research

Temple researchers identify criteria to predict cytokine storm in COVID-19 patients

Temple researchers identify criteria to predict cytokine storm in COVID-19 patients

Exuberant activation of immune cells in severe COVID-19 resembles lupus

Exuberant activation of immune cells in severe COVID-19 resembles lupus

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

New biomarker may help identify patients at risk for graft-versus-host disease after stem cell transplants

Auto-antibodies may explain why some people develop severe COVID-19

Auto-antibodies may explain why some people develop severe COVID-19

Targeted treatment for systemic lupus erythematosus

Targeted treatment for systemic lupus erythematosus

Biologic therapy for psoriasis could lead to significant reduction in heart disease

Biologic therapy for psoriasis could lead to significant reduction in heart disease

Important factors for a smooth transition from pediatric to adult rheumatology care

Important factors for a smooth transition from pediatric to adult rheumatology care

Memory B cells indicate durable immunity in COVID-19

Memory B cells indicate durable immunity in COVID-19

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Reformulated generic drug could offer a cost-effective way to accelerate recovery, prevent hospitalizations

Pharmaceutical researchers aim to create better CBD-like treatments

Pharmaceutical researchers aim to create better CBD-like treatments

Study: Hydroxychloroquine plus azithromycin linked to significant cardiovascular risks

Study: Hydroxychloroquine plus azithromycin linked to significant cardiovascular risks

Advances in Virus Epigenetics

Advances in Virus Epigenetics

Hydroxychloroquine is not a possible defense against COVID-19, study shows

Hydroxychloroquine is not a possible defense against COVID-19, study shows

Don’t fall for this video: Hydroxychloroquine is not a COVID-19 cure

Don’t fall for this video: Hydroxychloroquine is not a COVID-19 cure

Mysterious enzyme inhibits inflammation in blood vessels, LJI study shows

Mysterious enzyme inhibits inflammation in blood vessels, LJI study shows

Evidence of SARS-CoV-2 placental infection in mild COVID-19

Evidence of SARS-CoV-2 placental infection in mild COVID-19

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

One in three young adults at a higher risk of severe COVID-19 due to smoking, vaping

Study shows smoking is associated with a higher likelihood of COVID-19 progression

Study shows smoking is associated with a higher likelihood of COVID-19 progression

New method helps pinpoint new potential therapeutic targets for lupus

New method helps pinpoint new potential therapeutic targets for lupus

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children

Research sheds light on mysterious COVID-19 related hyperinflammatory shock in children