Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Overview

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Latest Lupus News and Research

Glycosylation emerges as a key player in kidney disease progression

Glycosylation emerges as a key player in kidney disease progression

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

Antibiotics in pregnancy and infancy do not raise autoimmune disease risk in children

New core dataset advances standardized care and research in systemic lupus erythematosus

New core dataset advances standardized care and research in systemic lupus erythematosus

Johns Hopkins team develops a more reliable AI for early cancer detection

Johns Hopkins team develops a more reliable AI for early cancer detection

New nanoparticle drug delivery system targets the spleen for precise lupus treatment

New nanoparticle drug delivery system targets the spleen for precise lupus treatment

Implant system can treat Type 1 diabetes by supplying extra oxygen to insulin-secreting cells

Implant system can treat Type 1 diabetes by supplying extra oxygen to insulin-secreting cells

Understanding sex-based differences in immune system function

Understanding sex-based differences in immune system function

Sugarcoating hides cellular RNA from the immune system

Sugarcoating hides cellular RNA from the immune system

Lupus Research Alliance awards early career scientists for innovative research

Lupus Research Alliance awards early career scientists for innovative research

New treatment approach developed to prevent lupus nephritis

New treatment approach developed to prevent lupus nephritis

New research links age-related gene changes to symptom decline

New research links age-related gene changes to symptom decline

Hispanic people more likely to develop peripheral neuropathy than white adults

Hispanic people more likely to develop peripheral neuropathy than white adults

HHS eliminates CDC staff who made sure birth control is safe for women at risk

HHS eliminates CDC staff who made sure birth control is safe for women at risk

Study finds nearly double risk of depression and anxiety in autoimmune patients

Study finds nearly double risk of depression and anxiety in autoimmune patients

Endometriosis linked to higher odds of autoimmune conditions

Endometriosis linked to higher odds of autoimmune conditions

Researchers turn a deadly fungus into potent cancer-fighting compound

Researchers turn a deadly fungus into potent cancer-fighting compound

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

An Arm and a Leg: A mathematical solution for US hospitals?

An Arm and a Leg: A mathematical solution for US hospitals?

SLIRP protein identified as key regulator of immune responses

SLIRP protein identified as key regulator of immune responses

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