Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Lupus, also called systemic lupus erythematosus or SLE, is a disease that affects your immune system. Normally, your immune system fights infections caused by germs.

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Latest Lupus News and Research

Common gene expression changes at target tissues of four autoimmune diseases found

Common gene expression changes at target tissues of four autoimmune diseases found

New approach can help identify novel treatments for autoimmune diseases

New approach can help identify novel treatments for autoimmune diseases

Main bioactive compound of ginger root may protect against autoimmune disease progression

Main bioactive compound of ginger root may protect against autoimmune disease progression

Monitoring patients' hydroxychloroquine blood levels can predict their clotting risk

Monitoring patients' hydroxychloroquine blood levels can predict their clotting risk

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

Researchers are developing new criteria for clinical research of antiphospholipid syndrome

LRA survey: Two-thirds of people with lupus are willing to take COVID-19 vaccine

LRA survey: Two-thirds of people with lupus are willing to take COVID-19 vaccine

Pulmonary hypertension drug may become a treatment option for cancer

Pulmonary hypertension drug may become a treatment option for cancer

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

Study provides mechanistic insights about the role of neutrophils in psoriasis pathogenesis

TTUHSC professor receives 2020 Lupus Mechanisms and Targets Award

TTUHSC professor receives 2020 Lupus Mechanisms and Targets Award

Steroids used to treat inflammatory disease increases risk of cardiovascular disease

Steroids used to treat inflammatory disease increases risk of cardiovascular disease

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Research provides deeper insight into the pathogenesis of sclerodermatous chronic GVHD

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Study reveals the metabolic signaling mechanisms that regulate function of eTreg cells

Study investigates possible link between sleep apnea and autoimmune diseases

Study investigates possible link between sleep apnea and autoimmune diseases

Lupus Research Alliance announces the 2020 Lupus Innovation Awards

Lupus Research Alliance announces the 2020 Lupus Innovation Awards

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

HSS presents research related to rheumatology and orthopedic surgery at 2020 ACR annual meeting

Mymee's clinical trial demonstrates health-related quality of life improvements in lupus patients

Mymee's clinical trial demonstrates health-related quality of life improvements in lupus patients

Study: Hydroxychloroquine has no effect on abnormal heart rhythm in lupus patients with CKD

Study: Hydroxychloroquine has no effect on abnormal heart rhythm in lupus patients with CKD

Black patients with lupus have higher risk of stroke and ischemic heart disease

Black patients with lupus have higher risk of stroke and ischemic heart disease

Lupus patients receiving prophylactic therapy are at high risk for adverse reactions

Lupus patients receiving prophylactic therapy are at high risk for adverse reactions

Patients with rheumatic diseases reported antimalarial drug shortages during COVID-19

Patients with rheumatic diseases reported antimalarial drug shortages during COVID-19