Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Latest Lupus News and Research

New anti-lipid antibodies could improve diagnosis of Lyme disease

New anti-lipid antibodies could improve diagnosis of Lyme disease

HSS researchers link early-life immunity to adult immune function

HSS researchers link early-life immunity to adult immune function

Scientists find link between bacterium in the gut ecosystem and lupus

Scientists find link between bacterium in the gut ecosystem and lupus

Immune cells drive abnormal joint tissue growth in rheumatoid arthritis

Immune cells drive abnormal joint tissue growth in rheumatoid arthritis

Researchers uncover key mechanism driving chronic Sjögren disease

Researchers uncover key mechanism driving chronic Sjögren disease

Philanthropic investment expands collaborative network for autoimmune research

Philanthropic investment expands collaborative network for autoimmune research

Review finds vitamin D lacks disease-modifying effect in rheumatic diseases

Review finds vitamin D lacks disease-modifying effect in rheumatic diseases

GLP-1 therapies linked to fewer complications in adults with both obesity and autoimmune disease

GLP-1 therapies linked to fewer complications in adults with both obesity and autoimmune disease

Patient organizations strengthen support for people with rheumatic diseases

Patient organizations strengthen support for people with rheumatic diseases

EULAR 2026 highlights rising comorbidity risks in rheumatic disease

EULAR 2026 highlights rising comorbidity risks in rheumatic disease

CAR-T cell therapy shows promise for treating rheumatoid arthritis

CAR-T cell therapy shows promise for treating rheumatoid arthritis

Modified stem cell therapy reverses new-onset Type 1 diabetes in mice

Modified stem cell therapy reverses new-onset Type 1 diabetes in mice

Mount Sinai study links long COVID symptoms to autoimmunity

Mount Sinai study links long COVID symptoms to autoimmunity

Hydroxychloroquine lowers heart risks in skin lupus patients

Hydroxychloroquine lowers heart risks in skin lupus patients

Study reveals why women face higher autoimmune disease risks

Study reveals why women face higher autoimmune disease risks

Scientists redesign CAR-T cells to fight more than cancer

Scientists redesign CAR-T cells to fight more than cancer

High levels of gut bacterial toxin linked to increased lupus nephritis risk

High levels of gut bacterial toxin linked to increased lupus nephritis risk

Researchers identify molecular link between autoimmune disease and lymphoma risk

Researchers identify molecular link between autoimmune disease and lymphoma risk

FDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditions

FDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditions

CAR T therapy induces remission in multiple autoimmune diseases

CAR T therapy induces remission in multiple autoimmune diseases

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