Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Latest Lupus News and Research

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Study establishes a feasible combination therapeutic strategy for ulcerative colitis

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Duration of infectiousness, predictors of ongoing individual infectiousness, and diagnostic tests for acute SARS-CoV-2 infection

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Study explores the effect of age-associated B cells on COVID-19 vaccine-induced immunity

Patients with autoimmune diseases at greater risk of complications after heart attack

Patients with autoimmune diseases at greater risk of complications after heart attack

New data analysis approach could help uncover the genetic basis of many diseases

New data analysis approach could help uncover the genetic basis of many diseases

Novel 3D-printed light-sensing medical device could help millions of lupus patients

Novel 3D-printed light-sensing medical device could help millions of lupus patients

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

Clinical trial shows efficacy and safety of belimumab in East Asian adults with lupus nephritis

The origins, breadth, and resolution of autoreactivity in severe COVID-19

The origins, breadth, and resolution of autoreactivity in severe COVID-19

People with autoimmune disorder have a higher risk of developing cardiovascular disease

People with autoimmune disorder have a higher risk of developing cardiovascular disease

Study reveals safety and uptake of sotrovimab against severe SARS-CoV-2 infection in England

Study reveals safety and uptake of sotrovimab against severe SARS-CoV-2 infection in England

Scientists begin phase 2 clinical trials of lupus pill

Scientists begin phase 2 clinical trials of lupus pill

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

The QCOVID4 algorithm developed using data from the Omicron wave identifies those at highest risk of severe COVID-19 outcomes

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

New anti-cancer drug candidate is absorbed through the lymphatic system rather than blood vessels

Clinical and demographic inequalities in COVID-19-associated mortality

Clinical and demographic inequalities in COVID-19-associated mortality

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

ADAR1 mutation sets off biochemical pathways that produce an organ-damaging autoimmune response

Because of Texas abortion law, her wanted pregnancy became a medical nightmare

Because of Texas abortion law, her wanted pregnancy became a medical nightmare

Three things about the abortion debate that many people get wrong

Three things about the abortion debate that many people get wrong

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

UT Southwestern physicians outline the risks of pregnancy in women with rheumatic disease

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Chemokine-DNA nanoparticles can induce chronic, dysfunctional immune responses

Video game intervention improves attention and executive functioning in patients with lupus

Video game intervention improves attention and executive functioning in patients with lupus