Lupus

Systemic lupus erythematosus (SLE), also called lupus, is an autoimmune disorder characterized by the immune system attacking the body's own tissues and organs, leading to inflammation and damage. The severity of the disease varies, from mild cases only involving the skin to severe cases affecting multiple organs, including the brain. Lupus sufferers experience flares, or intervals of active disease, and remissions in disease. The disease most predominantly occurs in women of childbearing age, but also affects children, adolescents, and men. While the cause of lupus is still unknown, various genetic, environmental, and infectious causes have been associated with its development. Current treatments for lupus vary depending on the extent of the disease, and may change over time. Some medications used to ease symptoms include nonsteroidal anti-inflammatory drugs, antimalarial drugs, corticosteroids, and immunosuppressive medications, though many of these drugs carry their own risks.
What is Lupus?

Systemic lupus erythematosus (SLE), which is more commonly referred to as lupus, is a disease that affects the immune system.

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Overview

Feature Articles

Latest Lupus News and Research

Researchers identify molecular link between autoimmune disease and lymphoma risk

Researchers identify molecular link between autoimmune disease and lymphoma risk

FDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditions

FDA clears investigational new drug application to test sCAR-T therapy for autoimmune conditions

CAR T therapy induces remission in multiple autoimmune diseases

CAR T therapy induces remission in multiple autoimmune diseases

Future CAR therapy expands beyond T cells to treat diverse diseases

Future CAR therapy expands beyond T cells to treat diverse diseases

New compounds reduce inflammation without weakening immune defense

New compounds reduce inflammation without weakening immune defense

Cancer-fighting antibodies may trigger autoimmune brain disorders

Cancer-fighting antibodies may trigger autoimmune brain disorders

Existing medication could improve the health of people living with HIV

Existing medication could improve the health of people living with HIV

Psychiatrists’ use of biomarkers could open a new window into mental health diagnoses

Psychiatrists’ use of biomarkers could open a new window into mental health diagnoses

Updated guideline emphasizes earlier treatment for high cholesterol

Updated guideline emphasizes earlier treatment for high cholesterol

Simplified nanoparticles "educate"  the immune system to find and destroy disease-causing cells

Simplified nanoparticles "educate" the immune system to find and destroy disease-causing cells

NIH grant supports Oklahoma researcher investigating protein linked to lupus

NIH grant supports Oklahoma researcher investigating protein linked to lupus

New research initiative aims to predict and prevent diseases before they start

New research initiative aims to predict and prevent diseases before they start

Macrophage immune memory depends on lingering interferon gamma

Macrophage immune memory depends on lingering interferon gamma

EBV-linked killer T cells implicated in multiple sclerosis

EBV-linked killer T cells implicated in multiple sclerosis

Study tests digital energy management tool for Long COVID

Study tests digital energy management tool for Long COVID

Epstein-Barr virus together with a gene variant contributes to onset of multiple sclerosis

Epstein-Barr virus together with a gene variant contributes to onset of multiple sclerosis

Silica nanomatrix enhances immunotherapy for solid tumors

Silica nanomatrix enhances immunotherapy for solid tumors

Air pollution and immune changes could trigger autoimmune conditions

Air pollution and immune changes could trigger autoimmune conditions

Exploring melatonin therapeutic potential in systemic lupus erythematosus

Exploring melatonin therapeutic potential in systemic lupus erythematosus

A 36-week screening strategy safely reduces pre-eclampsia at term

A 36-week screening strategy safely reduces pre-eclampsia at term

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