Lupus News and Research

Latest Lupus News and Research

Researchers turn a deadly fungus into potent cancer-fighting compound

Penn-led researchers have turned a deadly fungus into a potent cancer-fighting compound. After isolating a new class of molecules from Aspergillus flavus, a toxic crop fungus linked to deaths in the excavations of ancient tombs, the researchers modified the chemicals and tested them against leukemia cells.

23 Jun 2025

Transfer RNA-derived small RNAs transform the landscape of liquid biopsy

A new review highlights the transformative potential of transfer RNA-derived small RNAs (tsRNAs) in the field of liquid biopsy, emphasizing their role as promising biomarkers for a wide range of diseases, particularly cancers.

20 Jun 2025

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD).

15 Jun 2025

An Arm and a Leg: A mathematical solution for US hospitals?

What do the KGB and the former CEO of Cincinnati Children’s Hospital have in common?

4 Jun 2025

SLIRP protein identified as key regulator of immune responses

Even after the COVID-19 pandemic, various new infectious diseases continue to emerge, posing ongoing viral threats that demand robust and sustained immune defenses.

15 May 2025

Cardiovascular mortality higher in women with rheumatoid arthritis and lupus

Women with the autoimmune diseases rheumatoid arthritis, lupus or systemic sclerosis may have a higher rate of death related to cardiovascular disease than men with the autoimmune diseases, according to new research published in the American Heart Association's journal Circulation: Cardiovascular Quality and Outcomes.

6 May 2025

Gut immune cells linked to worsening rheumatoid arthritis

After spending years tracing the origin and migration pattern of an unusual type of immune cell in mice, researchers have shown in a new study how activity of "good" microbes in the gut is linked to rheumatoid arthritis and, potentially, other autoimmune diseases.

2 May 2025

Mediterranean diet helps manage rheumatoid arthritis and Hashimoto’s, study shows

The Mediterranean diet shows promise in managing both systemic and organ-specific autoimmune diseases, including rheumatoid arthritis and autoimmune thyroiditis. Its anti-inflammatory and microbiota-modulating properties may reduce disease activity and improve metabolic outcomes.

23 Apr 2025

Understanding the complex spectrum of Castleman disease

Castleman disease (CD) is a rare, non-clonal lymphoproliferative disorder that manifests with a wide range of histologic and clinical features.

11 Apr 2025

Calibr-Skaggs receives FDA approval to test sCAR-T therapy in patients with autoimmune diseases

Calibr-Skaggs Institute for Innovative Medicines, the drug discovery division of Scripps Research, announced today that the FDA has cleared their investigational new drug (IND) application to study switchable chimeric antigen receptor T cell (sCAR-T) therapy (CLBR001 + SWI019) in patients with autoimmune conditions.

9 Apr 2025

Breakthrough research identifies small peptide for psoriasis treatment

Birmingham scientists have shown that a sequence of just three amino acids may reduce the severity of psoriasis, when applied topically in an emollient cream.

3 Apr 2025

Texas A&M research sheds light on Giardia and Cryptosporidium pathogens in canine facilities

The pathogens Giardia duodenalis and Cryptosporidium are common causes of sometimes-fatal intestinal diseases in humans, other mammals and birds worldwide.

2 Apr 2025

Annual COVID-19 boosters crucial for immunocompromised individuals

New research findings provide solid evidence that annual COVID-19 vaccine booster doses continue to be advisable for certain immunocompromised people, researchers at McGill University say.

1 Apr 2025

Study explores how sex chromosomes and hormones influence immune responses

Women have a higher proportion of key immune cells between puberty and menopause, which may be linked to the sex hormone estrogen and explain why they are less susceptible to certain infectious diseases than men, according to a new study led by researchers at UCL.

27 Mar 2025

Fusion proteins enable the creation of monoclonal antibodies

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to advance research projects.

26 Mar 2025

Cedars-Sinai study shows rapid healing of heart damage with cell therapy

A scientific technique that rapidly increases the body's production of anti-inflammatory cells promoted healing from heart attacks in mice, according to a new study by investigators from the Smidt Heart Institute at Cedars-Sinai. Once adapted to treat humans, the technique could potentially be used to repair heart muscle damage after a heart attack and be applied to a variety of inflammatory disorders.

26 Mar 2025

Yale study unlocks potential of lupus-related antibody to target cold tumors

Yale scientists have discovered a promising way to trigger immune responses against certain tumors, using a lupus-related antibody that can slip, undetected, into "cold" tumors and flip on an immune response that has been turned off by cancer.

25 Mar 2025

Understanding the role of iron-dependent ferroptosis in immune suppression

Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

24 Mar 2025

Fighting cancer, inflammation and unlocking dementia diagnostics

In recognition of their discovery of one of our immune system’s foundations, physician Andrea Ablasser, virologist Glen Barber and biochemist Zhijian J. Chen will be awarded the Paul Ehrlich and Ludwig Darmstaedter Prize 2025, endowed with €120,000, in Frankfurt’s Paulskirche today.

14 Mar 2025