Melanoma News and Research

Latest Melanoma News and Research

Molecular superfamily causes melanoma spread

Molecular superfamily causes melanoma spread A superfamily of molecules holds the secret to the development and spread of melanoma - the deadliest form of skin cancer, revealed a study published in the British Journal of Cancer.

13 May 2009

Imiquimod, a topical cream, may help treat skin cancer

In a case study of a type of melanoma skin cancer typically found on chronically sun-exposed skin, Saint Louis University researchers found that imiquimod, a topical cream, produced good results for patients when used together with surgery to treat the cancer, potentially helping doctors cut less.

30 Apr 2009

Scientists develop drugs to block skin cancer protein

Scientists have developed a potent group of potential drug candidates to treat skin cancer, according to a study in the Journal of Medicinal Chemistry today (Thursday).

22 Apr 2009

Engineered antibody gives cancer the recognition it deserves

In concept, the human immune system has the power to destroy cancer cells with great specificity.

22 Apr 2009

AEterna Zentaris presents results for AEZS-112 in advanced cancer and lymphoma

AEterna Zentaris Inc. has presented a poster outlining Phase 1 results for its orally-active tubulin and topoisomerase II inhibitor compound, AEZS-112, in patients with advanced solid tumors or lymphoma, which may potentially provide a new therapeutic approach for the treatment of cancer.

22 Apr 2009

Genetic variants in MC1R could help predict melanoma risk

New genetic research suggests that the traditional risk factors for melanoma may not be as helpful in predicting risk in all people as previously thought, according to data presented at the American Association for Cancer Research 100th Annual Meeting 2009.

22 Apr 2009

Survey identifies factors associated with early detection of melanoma in older men

Older men whose melanoma is detected by a physician are more likely to have thinner and therefore more treatable tumors at diagnosis, according to results of a survey published in the April issue of Archives of Dermatology.

21 Apr 2009

Removal of ovaries during hysterectomy increases risk of death, outweighs benefits

Results of a landmark study led by a doctor at John Wayne Cancer Institute at Saint John's Health Center raises serious questions about the long-term survival benefits of removing a woman's ovaries during routine hysterectomy.

20 Apr 2009

Nanoparticle delivery of a fully functioning copy of P53 tumor suppressor gene

Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing normal tissue April 21 at an American Association of Anatomists (AAA) scientific session at Experimental Biology 2009 in New Orleans.

20 Apr 2009

Brain metastases hijack neuron-supporting cells to resist chemotherapy

Cancer that spreads to other organs finds a particularly inviting hideout in the brain, where these metastases are usually far harder to treat than they are in other locations.

20 Apr 2009

Protein Mcl-1 identified as new therapeutic target for melanoma

A protein called Mcl-1 plays a critical role in melanoma cell resistance to a form of apoptosis called anoikis, according to research published this week in Molecular Cancer Research.

16 Apr 2009

Gene mutation the trigger for deadly melanoma

According to British researchers as many as 70% of melanoma skin cancers may be triggered by a gene mutation.

13 Apr 2009

New approach for surveying phosphorylation

Scientists have developed a new approach for surveying phosphorylation, a process that is regulated by critical cell signaling pathways and regulates several key cellular signaling events.

12 Apr 2009

Researchers reveal how immune cells can be harnessed to target melanoma

Researchers at the Babraham Institute and the University of Catanzaro "Magna Graecia", Italy, co-ordinating an international network of scientists and clinicians from Europe, the USA and Japan, have identified new mechanisms through which the immune system recognises and responds to tumours like melanomas.

12 Apr 2009

Many skin cancer patients do not receive sentinel lymph node biopsy

Although clinical practice guidelines recommend sentinel lymph node (SLN) biopsy for many patients with clinically node-negative melanoma, a new analysis from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) has found approximately half of patients do not receive recommended evaluation of their lymph nodes and that the type of health insurance a patient has, the type of hospital delivering treatment, and the hospital's geographic region are all associated with provider compliance with those guidelines.

9 Apr 2009