Metabolic Syndrome News and Research

Latest Metabolic Syndrome News and Research

NEJM publishes positive clinical results from Phase 2 clinical study of volanesorsen

Isis Pharmaceuticals, Inc., the leader in RNA-targeted therapeutics, and Akcea Therapeutics, its wholly owned subsidiary, announced today that The New England Journal of Medicine (NEJM) has published positive clinical results from a Phase 2 clinical study evaluating volanesorsen (formerly ISIS-APOCIII Rx) in patients with very high to severely high triglycerides.

30 Jul 2015

Consumption of B-GOS prebiotic has positive effect on gut microbiota, immune systems of elderly people

Clasado Biosciences Limited, the producers and suppliers of the second generation prebiotic Bimuno, a unique trans-galactooligosaccharide, and the Department of Food and Nutritional Sciences, The University of Reading, UK, today announce the results of human research demonstrating the positive effects of an advanced prebiotic on the immune system of the elderly.

29 Jul 2015

New UTMB study finds no association between testosterone therapy and blood clots in veins

A new study from The University of Texas Medical Branch at Galveston of more than 30,000 commercially insured men is the first large comparative analysis to show that there is no link between testosterone therapy and blood clots in veins. The study found that middle-aged and older men who receive testosterone therapy are not at increased risk of this illness.

21 Jul 2015

Study finds gene linked to age-related obesity, diabetes

Practically everyone gets fatter as they get older, but some people can blame their genes for the extra padding. Researchers have shown that two different mutations in a gene called ankyrin-B cause cells to suck up glucose faster than normal, fattening them up and eventually triggering the type of diabetes linked to obesity.

14 Jul 2015

Akcea Therapeutics obtains FDA Orphan Drug Designation for volanesorsen

Akcea Therapeutics, a wholly-owned subsidiary of Isis Pharmaceuticals, Inc., announced today that the U.S. Food and Drug Administration has granted Orphan Drug Designation to volanesorsen (ISIS-APOCIIIRx) for the treatment of patients with Familial Chylomicronemia Syndrome (FCS).

6 Jul 2015

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

In the first study of its kind, Penn researchers have shown how an anti-diabetic drug can have variable effects depending on small natural differences in DNA sequence between individuals. Mitchell Lazar, MD, PhD, Raymond Soccio, MD, PhD, and colleagues at the Perelman School of Medicine at the University of Pennsylvania, aim to apply this knowledge to develop personalized approaches to treating diabetes and other metabolic disorders.

3 Jul 2015

Tree nut consumption associated with lower body weight and lower risk of obesity

In a study published this week in Nutrition Journal*, researchers compared risk factors for heart disease and metabolic syndrome of tree nut consumers versus those who did not consume tree nuts. Tree nut (almonds, Brazil nuts, cashews, hazelnuts, macadamias, pecans, pine nuts, pistachios and walnuts) consumption was associated with lower body mass index (p=0.004), systolic blood pressure (p=0.001), insulin resistance (p=0.043) and higher levels of high-density lipoprotein-cholesterol (good cholesterol) (p=0.022).

30 Jun 2015

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

'Walk through any supermarket and take a look at the labels on food products, and you'll see that many of them contain fructose, often in the form of sucrose (table sugar)' -- that's how Wilhelm Krek, professor for cell biology at ETH Zurich's Institute for Molecular Health Sciences, summarises the problem with today's nutrition.

18 Jun 2015

New book provides valuable information on childhood and adolescent obesity

Obesity is a major disease burden in all societies and needs to be prevented early in life. New approaches are eagerly sought and absolutely necessary. This new volume presents a wealth of information on childhood and adolescent obesity, from causes and consequences to societal aspects and prevention of obesity as well as its management.

16 Jun 2015

Study reveals new information about role of abdominal fat in teens with CAH

Researchers at Children's Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).

11 Jun 2015

LEO Pharma reports encouraging data from PSO-FAST clinical trial of Enstilar for psoriasis treatment

LEO Pharma A/S today announced that new data being presented at the 23rd World Congress of Dermatology shows aerosol foam Enstilar® (calcipotriol/betamethasone dipropionate 50 micrograms/g / 0,5 mg/g), the Company's dual-action investigational aerosol foam for the treatment of psoriasis vulgaris, provided rapid itch relief and improvements in itch-related sleep loss for patients suffering from psoriasis.

10 Jun 2015

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action.

22 May 2015

Study finds that nearly 35% of U.S. adults have metabolic syndrome

Nearly 35 percent of all U.S. adults and 50 percent of those 60 years of age or older were estimated to have the metabolic syndrome in 2011-2012, according to a study in the May 19 issue of JAMA.

19 May 2015

UK's leading experts to discuss new ideas and controversies in obesity at Plymouth symposium

No one health issue has the most impact on human health, or engenders more debate about how to tackle it, than obesity.

18 May 2015

Study finds extremely high levels of cardiovascular risk factors in people with psychosis

Extremely high levels of cardiovascular risk factors have been found in people with established psychosis, with central obesity evident in over 80 per cent of participants, in a study by researchers from the NIHR Biomedical Research Centre at the South London and Maudsley NHS Foundation Trust and King's College London.

12 May 2015

Dr. Philipp Scherer to receive prestigious Banting Medal for Scientific Achievement from ADA

Dr. Philipp Scherer, Director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, will receive the prestigious Banting Medal for Scientific Achievement, the highest honor bestowed by the American Diabetes Association.

30 Apr 2015

ATA guidelines provide recommendations for managing thyroid nodules and thyroid cancer in children

Previous guidelines from the American Thyroid Association for evaluating and managing thyroid nodules and thyroid cancers targeted adults. Recognizing the potential differences in clinical presentation and long-term outcomes, and the potential risks of overly aggressive therapy in pediatric patients with thyroid cancer, an ATA Task Force developed management guidelines for children with thyroid nodules and differentiated thyroid cancer (DTC), which are published in Thyroid, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers and the official journal of the American Thyroid Association.

23 Apr 2015

Study: Cardiorespiratory fitness associated with reduced metabolic syndrome risk among smokers

Cardiorespiratory fitness is associated with reduced metabolic syndrome risk among smokers, according to researchers from The University of Texas Health Science Center at Houston (UTHealth) School of Public Health.

17 Apr 2015

Exercise benefits obese, overweight people with NAFLD

Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the western world. A new study published in the Journal of Hepatology shows that exercise, regardless of frequency or intensity, benefits obese and overweight adults with NAFLD.

8 Apr 2015

Symposium to highlight latest thinking related to obesity

The 15th Plymouth Obesity, Diabetes and Metabolic Syndrome Symposium will take place at Plymouth Postgraduate Medical Centre on 21st May.

6 Apr 2015

Metabolic Syndrome News and Research

Latest Metabolic Syndrome News and Research

NEJM publishes positive clinical results from Phase 2 clinical study of volanesorsen

Consumption of B-GOS prebiotic has positive effect on gut microbiota, immune systems of elderly people

New UTMB study finds no association between testosterone therapy and blood clots in veins

Study finds gene linked to age-related obesity, diabetes

Akcea Therapeutics obtains FDA Orphan Drug Designation for volanesorsen

Penn study suggests future precision medicine approach to treating diabetes, other metabolic disorders

Tree nut consumption associated with lower body weight and lower risk of obesity

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

New book provides valuable information on childhood and adolescent obesity

Study reveals new information about role of abdominal fat in teens with CAH

LEO Pharma reports encouraging data from PSO-FAST clinical trial of Enstilar for psoriasis treatment

Splicing pattern of obesity, type 2 diabetes genes may contribute to pathophysiology of obesity

Study finds that nearly 35% of U.S. adults have metabolic syndrome

UK's leading experts to discuss new ideas and controversies in obesity at Plymouth symposium

Study finds extremely high levels of cardiovascular risk factors in people with psychosis

Dr. Philipp Scherer to receive prestigious Banting Medal for Scientific Achievement from ADA

ATA guidelines provide recommendations for managing thyroid nodules and thyroid cancer in children

Study: Cardiorespiratory fitness associated with reduced metabolic syndrome risk among smokers

Exercise benefits obese, overweight people with NAFLD

Symposium to highlight latest thinking related to obesity

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Metabolic Syndrome News and Research

Latest Metabolic Syndrome News and Research

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

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