Metabolism News and Research

Latest Metabolism News and Research

Researchers visualize protein machinery of respiration for the first time

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

31 Jan 2022

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

A University of South Florida Health preclinical study offers molecular insight into how activated protein C (APC) may improve aging patients' tolerance to reperfusion injury – a potentially adverse effect of treatment for ischemic heart disease.

31 Jan 2022

Study reveals potential mechanism for iron accumulation in the aging brain

Breakdowns in regulatory mechanisms cause iron to build up in the brain as organisms grow older, increasing oxidative stress and causing cellular damage, according to a Northwestern Medicine study published in the journal eLife.

31 Jan 2022

3C-like protease inhibitor clinical candidate, S-217622, as a treatment for SARS-CoV-2

In a new study, a team of researchers discovered S-217622, a non-covalent SARS-CoV-2 3C-like protease (3CLpro) inhibitor clinical candidate for the treatment of COVID-19.

31 Jan 2022

Study reveals link between muscular dystrophy and sphingolipids

In a new study, the group of Johan Auwerx at EPFL's School of Life Sciences has made the first connection between muscular dystrophy and sphingolipids, a group of bioactive lipids. The study is published in Science Advances.

29 Jan 2022

New study offers valuable information on ocular drug metabolism and pharmacokinetics

Severe visual illnesses are increasing in our society, and effective treatments are missing for diseases as age-related macular degeneration, diabetic retinopathy, and glaucoma. Both industry and academia are highly interested to advance ocular drug discovery and development.

29 Jan 2022

Study identifies genetic link between early maturation and high aerobic performance in juvenile salmon

A study conducted at the University of Helsinki indicates that early sexual maturation and high aerobic performance in salmon have a genetic link that is already evident in juvenile salmon.

28 Jan 2022

Studying the effect of COVID-19 mRNA vaccine on human lung carcinoma epithelial cells using Raman spectroscopy and imaging

Researchers from the Lodz University of Technology have been investigating the effects of the mRNA COVID-19 vaccines on human lung carcinoma cells.

28 Jan 2022

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

In a new study, researchers conducted activity-based proteomic profiling of patients who had severe SARS-CoV-2 infections to understand the impact of DNA clearance on mortality.

28 Jan 2022

Bisphenol A's effects are much worse than previously thought, experts say

The Endocrine Society joined a coalition of physicians, scientists and public health and environmental organizations to send a formal petition to the Food and Drug Administration (FDA), calling on the agency to rescind its approvals for bisphenol A (BPA) in adhesives and coatings and set strict limits on its use in plastics that contact food.

28 Jan 2022

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Hyaluronic acid, or HA, is a known presence in pancreatic tumors, but a new study from researchers at the University of Michigan Health Rogel Cancer Center shows that hyaluronic acid also acts as food to the cancer cells.

28 Jan 2022

Metabolic adaptation increases the length of time to achieve weight-loss goals

In women who are premenopausal with overweight, metabolic adaptation after a 16% weight loss increases the length of time necessary to achieve weight-loss goals, according to a study published online in Obesity, The Obesity Society's flagship journal.

27 Jan 2022

Curtailed sleep may increase exercise-induced cardiac strain

In a new study, participants underwent an intense bout of exercise after both normal sleep and after three nights of curtailed sleep.

27 Jan 2022

Northwestern and partners are part of mega NIH program to investigate precision nutrition

Northwestern, the University of Chicago, Illinois Institute of Technology, University of Illinois, Chicago and Rush University are part of a mega National Institutes of Health (NIH) $170 million program that is the first comprehensive study to investigate precision nutrition.

27 Jan 2022

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

Eating more meat, having less of certain bacteria in the gut, and more of certain immune cells in the blood, all link with multiple sclerosis, reports a team of researchers led by UConn Health and Washington University School of Medicine.

27 Jan 2022

Diet leaves permanent genetic alterations in the gut microbes

Our gut is inhabited by a diverse community of microbes, the gut microbiota. This community, composed of hundreds of different species, is essential to our health: it influences our immune system, protects us from infections, and helps us digest food.

27 Jan 2022

Study highlights the risk of kidney disease and obesity in people with type 1 diabetes

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

In a recent study, whole mRNA-seq was used to investigate the global effects of SARS-CoV-2 viral genes Nsp6, Nsp8, and M on the transcriptome of hPSC-CMs.

26 Jan 2022

Metabolism News and Research

Latest Metabolism News and Research

Researchers visualize protein machinery of respiration for the first time

Drugs derived from activated protein C may limit ischemia and reperfusion injury, study suggests

Study reveals potential mechanism for iron accumulation in the aging brain

3C-like protease inhibitor clinical candidate, S-217622, as a treatment for SARS-CoV-2

Study reveals link between muscular dystrophy and sphingolipids

New study offers valuable information on ocular drug metabolism and pharmacokinetics

Study identifies genetic link between early maturation and high aerobic performance in juvenile salmon

Studying the effect of COVID-19 mRNA vaccine on human lung carcinoma epithelial cells using Raman spectroscopy and imaging

Impact of DNA clearance on mortality in patients with severe COVID-19 infections

Bisphenol A's effects are much worse than previously thought, experts say

Hyaluronic acid acts as food to pancreatic cancer cells, study shows

Metabolic adaptation increases the length of time to achieve weight-loss goals

Curtailed sleep may increase exercise-induced cardiac strain

Northwestern and partners are part of mega NIH program to investigate precision nutrition

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

Diet leaves permanent genetic alterations in the gut microbes

Study highlights the risk of kidney disease and obesity in people with type 1 diabetes

Regular physical activity lowers type 2 diabetes risk by changing the body's metabolite profile

Gastrointestinal hormone shows promise for the treatment of heart and kidney failure

Study finds overexpression of 3 SARS-CoV-2 genes could globally compromise transcriptome of human pluripotent stem cell-derived cardiomyocytes

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