Metabolism News and Research

Latest Metabolism News and Research

Researchers investigate the role of a key component of the circadian clock in heart disease

Disrupting circadian rhythms, which change naturally on a 24-hour cycle, has been implicated in heart disease, but it is unclear how it leads to the condition.

17 Jan 2022

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

In a new study, researchers used per protocol bronchoalveolar lavage fluid (BALF) samples after intubation to evaluate the transcriptomic profiles of the local pulmonary host responses during early-stage severe coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (CARDS), non-COVID-19 ARDS, and sepsis.

17 Jan 2022

Research provides a comprehensive map of exercise-induced signaling molecules present in the tissues

It is well established that exercise improves health, and recent research has shown that exercise benefits the body in different ways, depending on the time of day. But scientists still do not know why the timing of exercise produces these different effects.

17 Jan 2022

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

A new study, posted to the bioRxiv* preprint server, has developed a single-cell atlas that presents the shared and distinct immune responses and metabolism following SARS-CoV-2 and HIV-1 infections.

13 Jan 2022

Study finds blunted cortisol profiles in women who experienced childhood sexual abuse

Childhood sexual abuse can lead to depression, anxiety, cardiovascular disease and other health problems later in life. Not all abused children experience these problems, however, and researchers are working to understand whose health is affected and why.

13 Jan 2022

Role of leptin in immune modulation and pathophysiology of COVID-19

A recent review paper in the journal Frontiers in Physiology discusses the role of leptins in infection with SARS-CoV-2 that triggered the ongoing COVID-19 pandemic.

13 Jan 2022

Metabolic vulnerabilities in malignant cells may lead to new breast cancer therapies

Metabolic differences could explain why some metastatic breast cancer cells rapidly generate tumors after migrating from primary tumors to the brain, while others linger for months or years before forming these secondary tumors, UT Southwestern scientists report in a new study.

12 Jan 2022

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Research led by scientists at the Jonsson Comprehensive Cancer Center (JCCC) at UCLA provides new insights into molecular "crosstalk" in pancreas cancer cells, identifying vulnerabilities that could provide a target for therapeutic drugs already being studied in several cancers.

12 Jan 2022

Discovery of new protein could lead to effective treatments for developmental, neurological disorders

Understanding how the brain develops is crucial to formulating treatments and management protocols for a variety of developmental disorders, as well as degenerative neurological diseases. Right from the embryonic stage, brain development is facilitated by the differentiation of neurons (brain cells).

12 Jan 2022

Study reveals the beneficial role of fat in type 2 diabetes

With nearly 10% of the world's population affected, type 2 diabetes is a major public health issue. An excessively sedentary lifestyle and a too-caloric diet encourage the development of this metabolic disease by altering the functioning of pancreatic cells and making blood sugar regulation less effective.

11 Jan 2022

Study reveals genomic regions that could help understand obesity

A new study has helped to shine light on the genetic pathways underlying obesity. The findings could help develop more personalized ways to help people maintain a healthy weight.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

Scientists shine new light on the complexity of vitamin B12 diseases

A team of researchers at Baylor College of Medicine and collaborating institutions has shed new light into the complexity of vitamin B12 diseases.

10 Jan 2022

Fewer than 1 in 5 U.S. adults with Type 2 diabetes meet targets to reduce heart disease risk

Fewer than 1 in 5 adults with Type 2 diabetes in the U.S. are meeting targets to reduce heart disease risk. Fortunately, available therapies can help when combined with new approaches that address social determinants of health and other barriers to care, according to a new American Heart Association scientific statement published today in the Association's flagship journal Circulation.

10 Jan 2022

Maternal thyroid hormone levels during pregnancy may predict children's behavioral problems

Thyroid hormone levels during pregnancy may predict preschool boys' emotional and behavioral problems, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

6 Jan 2022

New study strengthens the link between sleep-disordered breathing and gestational diabetes

Sleep-disordered breathing in early pregnancy is associated with insulin resistance or difficulty clearing glucose from the blood, suggests a small study funded by the National Institutes of Health.

6 Jan 2022

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one.

5 Jan 2022

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Aggressive and relatively common lymphomas called diffuse large B cell lymphomas (DLBCLs) have a critical metabolic vulnerability that can be exploited to trick these cancers into starving themselves, according to a study from researchers at Weill Cornell Medicine and Cornell's Ithaca campus.

3 Jan 2022

Study finds increased oxidative stress, oxidant damage and glutathione deficiency in COVID-19 patients

Researchers at Baylor College of Medicine have investigated the effect of infection with COVID-19 on the levels of oxidative stress, oxidant damage and glutathione, the most abundant physiological antioxidant.

3 Jan 2022

Metabolism News and Research

Latest Metabolism News and Research

Researchers investigate the role of a key component of the circadian clock in heart disease

Dexamethasone shown to upregulate innate and adaptive immune responses in COVID-19 acute respiratory distress syndrome patients

Research provides a comprehensive map of exercise-induced signaling molecules present in the tissues

Similarities and dissimilarities in immune responses and metabolism in SARS-CoV-2 and HIV-1 infections

Study finds blunted cortisol profiles in women who experienced childhood sexual abuse

Role of leptin in immune modulation and pathophysiology of COVID-19

Metabolic vulnerabilities in malignant cells may lead to new breast cancer therapies

UCLA study provides new insights into molecular 'crosstalk' in pancreas cancer cells

Discovery of new protein could lead to effective treatments for developmental, neurological disorders

Study reveals the beneficial role of fat in type 2 diabetes

Study reveals genomic regions that could help understand obesity

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Scientists shine new light on the complexity of vitamin B12 diseases

Fewer than 1 in 5 U.S. adults with Type 2 diabetes meet targets to reduce heart disease risk

Maternal thyroid hormone levels during pregnancy may predict children's behavioral problems

New study strengthens the link between sleep-disordered breathing and gestational diabetes

Drugs that block mineralocorticoid receptor may help protect bone cells during aging

Study finds critical metabolic vulnerability of diffuse large B cell lymphomas

Study finds increased oxidative stress, oxidant damage and glutathione deficiency in COVID-19 patients

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