Metabolism News and Research

Latest Metabolism News and Research

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

The ongoing COVID-19 pandemic, caused by SARS-CoV-2, is now established to be more likely to lead to symptomatic and serious illness in males relative to females. This may extend as far back as pregnancy, suggests a recent study.

31 Mar 2021

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

A mechanism has been identified that explains how physical exercise in pregnancy confers metabolic health benefits in offspring.

30 Mar 2021

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Primary sclerosing cholangitis (PSC) is a rare, chronic, inflammatory disease of the bile ducts and is difficult to treat, since its causes have not yet been adequately researched.

30 Mar 2021

Study explains the link between psoriasis treatment and cardiovascular diseases

Patients with psoriasis, an autoimmune skin disorder, often have cardiovascular disorders as well. Hence, it is important for patients and clinicians to understand how treatments for psoriasis may influence cardiovascular disease risks.

30 Mar 2021

Study reveals the structure of key enzyme that may advance cancer research

In order to develop more effective drugs against a range of cancers, researchers have been investigating the molecular structure of many diseased-linked enzymes in the body. An intriguing case in point is Taspase 1, a type of enzyme known as a protease.

30 Mar 2021

GlyNAC could improve many age-associated defects in older humans

A pilot human clinical trial conducted by researchers at Baylor College of Medicine reveals that supplementation with GlyNAC - a combination of glycine and N-acetylcysteine as precursors of the natural antioxidant glutathione - could improve many age-associated defects in older humans to improve muscle strength and cognition, and promote healthy aging.

29 Mar 2021

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems able to exploit this vulnerability.

29 Mar 2021

Corticosteroid therapy in pregnant women with COVID-19

A new study describes the outcome of corticosteroid use in pregnancy.

29 Mar 2021

Researchers examine circRNAs encoded by MERS-CoV, SARS-CoV-1 and SARS-CoV-2

New research published in Briefings in Bioinformaticsm has identified thousands of circRNAs in Betacoronaviruses, including MERS-CoV, SARS-CoV-1, and SARS-CoV-2, from the RNA-sequencing data of viral infections. These coronaviruses have a similar genomic structure with a diverse circRNA coding ability. Researchers have also systematically characterized circRNAs in coronaviruses, with regard to their size, sequence feature, expressions, genome, location preference, and functions. This opens the door to further explore and understand the mode of action of individual circRNAs in coronaviruses.

29 Mar 2021

Boerhavia diffusa possess potential therapeutic properties against COVID-19

Several companies and research groups have been searching for suitably docking ligands that inhibit the function of this protein. In a research paper recently published to the Springer journal VirusDisease by Surya & Praveen (March 6th, 2021) in silico docking simulations towards 3CLpro have been performed, focusing in particular on natural products obtained from the plant Boerhavia diffusa.

28 Mar 2021

Mimicking stress signals can protect the brain and retina from aging

How do different parts of the body communicate? Scientists at St. Jude are studying how signals sent from skeletal muscle affect the brain.

27 Mar 2021

Researchers identify new targets for minimizing tooth sensitivity to cold

Researchers report in Science Advances that they have uncovered a new function for odontoblasts, the cells that form dentin, the shell beneath the tooth's enamel that encases the soft dental pulp containing nerves and blood vessels.

27 Mar 2021

UVA scientists identify a potential way to prevent heart attacks and strokes

Scientists at the University of Virginia School of Medicine have identified a potential way to head off heart attacks and strokes by strengthening the fibrous caps overlying atherosclerotic plaques that naturally accumulate inside our arteries.

27 Mar 2021

Researchers develop first human model for studying the neuronal pathology of Leigh syndrome

Leigh syndrome is the most severe mitochondrial disease in children. It causes severe muscle weakness, movement defects, and intellectual disabilities.

26 Mar 2021

The pressure is on to diagnose and treat chronic kidney disease

In this interview, Helen Yeh, the Vice President, Biopharmaceuticals Medical, Cardiovascular, Renal and Metablosim at AstraZeneca , talks News-Medical to about chronic kidney diseas (CKD).

From AstraZeneca 26 Mar 2021

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Altered cellular energetics, a hallmark of cancers, has been associated with obesity. However, links between systemic energy regulation and aberrant cancer cell metabolism have been lacking.

25 Mar 2021

Study may provide an explanation for dawn phenomenon in patients with type 2 diabetes

Researchers at Baylor College of Medicine, Shandong University in China and other institutions may have found an explanation for dawn phenomenon, an abnormal increase of blood sugar only in the morning, observed in many patients with type 2 diabetes.

25 Mar 2021

Study examines the health effects of diet and resistance training in middle-aged adults

A 10-week muscle-building and dietary program involving 50 middle-aged adults found no evidence that eating a high-protein diet increased strength or muscle mass more than consuming a moderate amount of protein while training.

25 Mar 2021

Study identifies gene variants that cause metabolic deficiency in the eye

Treatments for a rare retinal disease may be on the horizon after a new study has identified gene variants that cause a metabolic deficiency in the eye.

25 Mar 2021

New study shows large within- and between-assay variation for ß-CTX measurement

A new study by the IFCC‑IOF Committee for Bone Metabolism shows large within- and between-assay variation for ß-CTX measurement; until harmonization is achieved, proposes measuring ß-CTX by the same assay on EDTA plasma, especially for research.

25 Mar 2021

Metabolism News and Research

Latest Metabolism News and Research

Male fetuses impair the maternal and placental immune response to SARS-CoV-2 infection in pregnancy, finds study

Study reveals how exercise during pregnancy confers metabolic health benefits in offspring

Research consortium identifies cell stress mechanisms for chronic inflammatory liver disease

Study explains the link between psoriasis treatment and cardiovascular diseases

Study reveals the structure of key enzyme that may advance cancer research

GlyNAC could improve many age-associated defects in older humans

Diabetes drug appears to exploit vulnerability of AIDS-causing retrovirus HIV

Corticosteroid therapy in pregnant women with COVID-19

Researchers examine circRNAs encoded by MERS-CoV, SARS-CoV-1 and SARS-CoV-2

Boerhavia diffusa possess potential therapeutic properties against COVID-19

Mimicking stress signals can protect the brain and retina from aging

Researchers identify new targets for minimizing tooth sensitivity to cold

UVA scientists identify a potential way to prevent heart attacks and strokes

Researchers develop first human model for studying the neuronal pathology of Leigh syndrome

The pressure is on to diagnose and treat chronic kidney disease

Researchers reveal a mechanistic link in kidney cancer between fat metabolism and obesity

Study may provide an explanation for dawn phenomenon in patients with type 2 diabetes

Study examines the health effects of diet and resistance training in middle-aged adults

Study identifies gene variants that cause metabolic deficiency in the eye

New study shows large within- and between-assay variation for ß-CTX measurement

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