Metabolism News and Research

Latest Metabolism News and Research

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

An international clinical trial that used genetic testing to guide which antiplatelet medication was given to patients following percutaneous coronary intervention (PCI) did not meet its stated goal for cutting in half the incidence of serious adverse cardiovascular events, such as heart attack and stroke, in the year following the procedure.

30 Mar 2020

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Results from two subgroup analyses of the Phase IV independent TWILIGHT trial funded by AstraZeneca showed Brilinta (ticagrelor) monotherapy reduced the risk of clinically relevant bleeding over 12 months compared to aspirin plus Brilinta in high-risk coronary patients.

From AstraZeneca 30 Mar 2020

Research could open up new therapeutic strategies for some lung and kidney cancers

New findings from researchers at The University of Texas MD Anderson Cancer Center about how some cancer cells become "addicted" to glucose could open up fresh approaches to therapy strategies for cancers with high levels of an amino acid transporter called solute carrier family 7 member 11 (SLC7A11).

30 Mar 2020

Scientists model human CMV-induced microcephaly using brain organoids

A City of Hope scientist is one step closer to discovering what weakens a pathogen that appears to cause babies to be born with abnormally small heads.

30 Mar 2020

Weakness in lung and kidney cancer cells could serve as therapeutic target

An important discovery about how some cancers rely on glucose to survive could lead to development of tumor-specific treatments.

30 Mar 2020

Study shows how copper boosts pig growth

Pigs have better feed conversion rates with copper in their diets, but until now, scientists didn't fully understand why.

27 Mar 2020

Rheumatism: New clues about the prevalence of certain genetic profile in Europeans

A piece of research by the Human Evolutionary Biology Group at the UPV/EHU-University of the Basque Country provides clues about the prevalence of a certain genetic profile in the European population.

27 Mar 2020

Fast-acting anti-malarial compound shows promise in first clinical trial

A fast-acting anti-malarial compound discovered at St. Jude Children's Research Hospital was well tolerated and showed promising anti-malarial effects in the first study in humans.

27 Mar 2020

Factors causing childhood obesity differ for wealthier and poorer countries

Childhood obesity is not just a public health concern in western countries; it is rising across the world, particularly in poor and low-income countries.

26 Mar 2020

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Oncotarget Volume 11, Issue 12 reported that using the HL-60 human non-APL AML model where ATRA causes nuclear enrichment of c-Raf that drives differentiation/G0-arrest, the research team now observe that roscovitine enhanced nuclear enrichment of certain traditionally cytoplasmic signaling molecules and enhanced differentiation and cell cycle arrest.

26 Mar 2020

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW-Madison study shows.

26 Mar 2020

Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells

Scientists have innovated a potential method of preventing Type 1 diabetes in those at high risk.

26 Mar 2020

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Lonza is a large, multinational corporation serving the entire pharmaceutical product development and manufacturing pipeline, from non-clinical research products to final dosage and delivery solutions.

From Lonza 26 Mar 2020

Diet, nutrition have profound impact on microbial composition in the gut

Nutrition and diet have a profound impact on microbial composition in the gut, in turn affecting a range of metabolic, hormonal, and neurological processes, according to a literature review by scientists from the George Washington University and the National Institute of Standards and Technology.

25 Mar 2020

Novel PET/CT systems provide quantitative assessment of brain stem nuclei in patients with hearing loss

Novel, fully digital, high-resolution positron emission tomography/computed tomography (PET/CT) imaging of small brain stem nuclei can provide clinicians with valuable information concerning the auditory pathway in patients with hearing impairment, according to a new study published in the March issue of The Journal of Nuclear Medicine.

25 Mar 2020

Scientists discover tuberculosis bacterium channels vitamins into the cell

A new study published in the journal Nature in March 2020 reports a unique transport protein found within the tubercle bacillus, Mycobacterium tuberculosis. This huge membrane-spanning vesicular protein is different from other transport proteins and is instrumental in carrying hydrophilic molecules, notably vitamin B12 or cobalamin, across the cell membrane.

24 Mar 2020

Metabolism News and Research

Latest Metabolism News and Research

Clinical trial using genetic testing to guide antiplatelet therapy post-PCI falls short of stated goal

TWILIGHT trial: Brilinta reduces bleeding compared to dual therapy in high-risk coronary patients

Research could open up new therapeutic strategies for some lung and kidney cancers

Scientists model human CMV-induced microcephaly using brain organoids

Weakness in lung and kidney cancer cells could serve as therapeutic target

Study shows how copper boosts pig growth

Rheumatism: New clues about the prevalence of certain genetic profile in Europeans

Fast-acting anti-malarial compound shows promise in first clinical trial

Factors causing childhood obesity differ for wealthier and poorer countries

Roscovitine enhances nuclear enrichment of traditionally cytoplasmic signaling molecules

Removing a gene prevents Type 1 diabetes in mice by disguising beta cells

Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells

Why Primary Cells Are Important for In Vitro ADME-Tox Studies

Diet, nutrition have profound impact on microbial composition in the gut

Novel PET/CT systems provide quantitative assessment of brain stem nuclei in patients with hearing loss

Scientists discover tuberculosis bacterium channels vitamins into the cell

Researchers show possibility to control cell bioenergetics by changing mitochondria content

Fatty acid-binding protein 4 plays an important role in kidney stone formation

Neurotensinergic neurons in the brainstem regulate non-REM sleep

Study sheds light on myelin's role in 'chemobrain' and multiple sclerosis

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy