Metabolism News and Research

Latest Metabolism News and Research

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

A frontline chemotherapy drug given to patients with pancreatic cancer is made less effective because similar compounds released by tumor-associated immune cells block the drug's action, research led by the University of Michigan Rogel Cancer Center found.

27 Mar 2019

Encapsulating human beta cells with immune-repelling protein restores glucose metabolism in diabetic mice

Encapsulating human stem-cell-derived beta cells in microcapsules made with a protein that repels key immune cells restored glucose metabolism in diabetic mice and protected the cells from immune system attack, preventing the buildup of inflammatory fibrotic tissue that has plagued previous trials of encapsulated beta cells.

27 Mar 2019

Male contraceptive pill crosses the human clinical trial hurdle

Birth control pills have been around for the past six decades but have been for use of women only. A team of researchers this week have announced the success of the first male birth control pill that could safely prevent pregnancy.

27 Mar 2019

Male contraceptive pill shown to be safe and tolerable in phase I trial

A potential new male birth control pill has been declared safe for use after a phase I trial showed that the once-daily capsule works without causing any significant side effects.

26 Mar 2019

A1c blood test found to be unreliable in diabetes diagnoses

Research has found that many cases of diabetes are missed when the hemoglobin A1c blood test is used solely to diagnose the disease.

26 Mar 2019

Researchers identify metabolic target to prevent or slow progression of heart failure

Researchers with The Ohio State University College of Medicine and The Ohio State University Wexner Medical Center have identified a metabolic process in the heart that, if treated, could someday prevent or slow the progression of heart failure.

26 Mar 2019

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

LNC Therapeutics, a French biotech company specializing in gut microbiome-based drug discovery, announced today the grant of the Cornell University (Ithaca, New-York, USA) patent relating to christensenella bacteria.

26 Mar 2019

VCU researchers home in on microRNA processing for new cancer therapies

More than a decade of research on the mda-7/IL-24 gene has shown that it helps to suppress a majority of cancer types, and now scientists are focusing on how the gene drives this process by influencing microRNAs.

26 Mar 2019

Researchers uncover mechanism that initiates sexual organs maturation

Puberty is a period of extensive changes of body morphology and function. As much as we are familiar with these life-altering changes, relatively little is known about what sets the whole process in motion.

26 Mar 2019

Benefits of osteoporosis treatment in postmenopausal women outweigh the perceived risks

The benefits of treating osteoporosis in postmenopausal women outweigh the perceived risks, according to a Clinical Practice Guideline issued today by the Endocrine Society. The Society introduced the guideline during a news conference on Monday at ENDO 2019, its annual meeting in New Orleans, La.

25 Mar 2019

Transgender men preserve their fertility potential after one year of testosterone therapy

Transgender men preserve their fertility potential even after one year of treatment with the male hormone testosterone, according to a study that will be presented Saturday at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

New guideline focuses on strategies to improve health of older adults with diabetes

Simplifying medication regimens and tailoring glycemic targets in older adults with diabetes improves adherence and avoids treatment-related complications, according to a Clinical Practice Guideline issued today by the Endocrine Society.

25 Mar 2019

Hemoglobin A1c blood test may underestimate prevalence of diabetes

Using the hemoglobin A1c blood test to diagnose diabetes tends to underestimate the prevalence of the disease, according to a new study to be presented Saturday, March 23 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Hemoglobin A1c blood test does not detect diabetes in most patients, shows study

The hemoglobin A1c blood test is widely used to diagnose type 1 and type 2 diabetes, but it is actually unable to detect the disease in most patients, according to a new study presented Saturday, March 23, at a news conference at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

A clinical trial of an experimental drug designed to treat cravings associated with opioid use disorder has begun in the National Institutes of Health Clinical Center.

22 Mar 2019

Researchers identify genes responsible for safener efficacy in grain sorghum

Weeds often emerge at the same time as vulnerable crop seedlings and sneak between plants as crops grow. How do farmers kill them without harming the crops themselves?

22 Mar 2019

High-fructose corn syrup fuels growth of colon tumors in mice

Consuming the equivalent of one can of soda per day caused mice predisposed to colon cancer to develop larger tumors, according to a study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

22 Mar 2019

Thermally abused cooking oil may promote progression of breast cancer

A new study in mice suggests that consuming the chemical compounds found in thermally abused cooking oil may trigger genetic changes that promote the progression of late-stage breast cancer.

22 Mar 2019

Combined glucocorticoid and antioxidant therapy could benefit premature babies

Scientists at the University of Cambridge have suggested that subtle changes to the drugs administered to mothers threatened with preterm birth or to premature babies could further improve clinical treatment and help increase their safety.

21 Mar 2019

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Androgens, commonly known as male hormones, stimulate prostate cancer cells to grow. Thus, many of the drugs to target that cancer focus on stopping androgen biosynthesis or blocking the androgen receptor. This standard treatment is known as androgen deprivation therapy.

20 Mar 2019

Metabolism News and Research

Latest Metabolism News and Research

Tumor-associated macrophages block activity of chemotherapy drug in pancreatic cancer

Encapsulating human beta cells with immune-repelling protein restores glucose metabolism in diabetic mice

Male contraceptive pill crosses the human clinical trial hurdle

Male contraceptive pill shown to be safe and tolerable in phase I trial

A1c blood test found to be unreliable in diabetes diagnoses

Researchers identify metabolic target to prevent or slow progression of heart failure

LNC Therapeutics announces grant of Cornell University patent relating to christensenella bacteria

VCU researchers home in on microRNA processing for new cancer therapies

Researchers uncover mechanism that initiates sexual organs maturation

Benefits of osteoporosis treatment in postmenopausal women outweigh the perceived risks

Transgender men preserve their fertility potential after one year of testosterone therapy

New guideline focuses on strategies to improve health of older adults with diabetes

Hemoglobin A1c blood test may underestimate prevalence of diabetes

Hemoglobin A1c blood test does not detect diabetes in most patients, shows study

NIH starts clinical trial of drug to treat cravings associated with opioid use disorder

Researchers identify genes responsible for safener efficacy in grain sorghum

High-fructose corn syrup fuels growth of colon tumors in mice

Thermally abused cooking oil may promote progression of breast cancer

Combined glucocorticoid and antioxidant therapy could benefit premature babies

Androgen receptor plays vital role in regulating multiple mitochondrial processes

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging