Metabolism News and Research

Latest Metabolism News and Research

Vitamin D supplementation less effective in the presence of obesity, shows study

A new Journal of Bone and Mineral Research study confirms that vitamin D supplementation is less effective in the presence of obesity, and it uncovers a biological mechanism to explain this observation.

21 Feb 2019

New technology measures hormones that influence reproductive health efficiently

The technology, developed by researchers at Imperial College London and The University of Hong Kong, can be used to measure hormones that affect fertility, sexual development and menstruation more quickly and cheaply than current methods.

21 Feb 2019

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

The medicinal powers of aspirin, digitalis, and the anti-malarial artemisinin all come from plants. A Salk Institute discovery of a potent neuroprotective and anti-inflammatory chemical in a native California shrub may lead to a treatment for Alzheimer's disease based on a compound found in nature.

21 Feb 2019

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Elizabeth Delacruz can't crawl or toddle around like most youngsters nearing their second birthday.

21 Feb 2019

Why melanoma tumors in the brain may be worse?

Melanoma tumors that have spread to the brain are equipped to thwart immunotherapies and targeted therapies that succeed against tumors growing in other sites.

20 Feb 2019

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

In pharmaceutical companies, rats are used commonly in nonclinical studies to investigate the safety, efficacy, and pharmacokinetic profiles of drug candidates before they are entered into clinical studies. Most compounds administered via the oral route are metabolized in the liver and intestine, so the metabolism is a key determinant of pharmacokinetics.

20 Feb 2019

Researchers identify multiple genetic variants associated with body fat distribution

A new breakthrough from the Genetic Investigation of Anthropometric Traits consortium, which includes many public health researchers from the University of North Carolina at Chapel Hill, identifies multiple genetic variants associated with how the body regulates and distributes body-fat tissue.

18 Feb 2019

High-protein and low-calorie diet helps older adults lose weight safely, shows study

A high-protein, low-calorie diet helps older adults with obesity lose more weight, maintain more muscle mass, improve bone quality and lose "bad" fat, according to results from a new randomized controlled trial led by Wake Forest University researcher Kristen Beavers.

15 Feb 2019

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Cholesterol carried in high-density lipoprotein particles, or HDL cholesterol, has been dubbed the good cholesterol, because people whose HDL levels are high have a lower risk of developing heart disease. That link was first established in 1977 and has been confirmed over and over in epidemiological studies.

15 Feb 2019

Study investigates the role of estrogen in controlling glucose homeostasis

The results of a recent Texas A&M University-led study provide insights into the mechanism by which estrogen can decrease insulin resistance and the production of glucose, reducing incidences of Type 2 diabetes mellitus.

13 Feb 2019

Microbiologists identify enzyme that makes Helicobacter so adaptable

The bacterial pathogen Helicobacter pylori owes its worldwide distribution to its genetic adaptability. Ludwig-Maximilians-Universitaet Munich microbiologists have identified an enzyme that plays a vital role in the flexible control of global gene expression in the species.

13 Feb 2019

Low-calorie meals have protective effect against some diseases, reveals research

The number of calories a person eats directly influences the performance of different cells. A group of researchers from the University of São Paulo has shown that low-calorie meals have a protective effect against some diseases.

13 Feb 2019

Researchers examine link between OSA and inflammation, organ damage

Voyagers no longer embark in search of the storied Fountain of Youth, but the quest for longevity is still very much alive for researchers.

12 Feb 2019

Lactate activates multiple genes that modulate neuronal activity

A genome-wide study led by Dean Pierre Magistretti sheds light on the mechanisms through which lactate regulates long-term memory formation and neuroprotection.

12 Feb 2019

Newly discovered genetic disorder opens way for future diabetes drugs

Knowledge of a newly discovered genetic disorder, which means that a person cannot produce the protein TXNIP (thioredoxin interacting protein) in their cells, can open for the development of new diabetes drugs.

12 Feb 2019

Cancer-promoting changes seen in lung cells soon after exposure to low-molecular weight PAHs

It is well known that exposure to high-molecular weight polycyclic aromatic hydrocarbons increases cancer risk, leading to regulation of compounds like benzo(a)pyrene.

12 Feb 2019

Protein released from fat in response to exercise improves health

It's well-known that exercise improves health, but understanding how it makes you healthier on a molecular level is the question researchers at Joslin Diabetes Center are answering.

12 Feb 2019

Targeting aging process itself can lead to better and more effective interventions

Medical care for older adults has long focused on preventing and treating chronic diseases and the conditions that come with them.

11 Feb 2019

Alzheimer's disease protection from exercise hormone irisin

Irisin is found to be protective against Alzheimer’s disease finds a new study. The results of the new study were published in the journal Nature Medicine.

11 Feb 2019

Study reveals how exercise may protect against Alzheimer's disease

Athletes know a vigorous workout can release a flood of endorphins: "feel-good" hormones that boost mood. Now there's evidence that exercise produces another hormone that may improve memory and protect against Alzheimer's disease, according to a study co-led by Ottavio Arancio, MD, PhD, a researcher at Columbia University's Vagelos College of Physicians and Surgeons and Taub Institute for Research on Alzheimer's Disease and the Aging Brain.

11 Feb 2019

Metabolism News and Research

Latest Metabolism News and Research

Vitamin D supplementation less effective in the presence of obesity, shows study

New technology measures hormones that influence reproductive health efficiently

Discovery of potent compound in native California shrub may lead to treatment for Alzheimer's

Scientists can monitor brain activity to predict epileptic seizures few minutes in advance

Why melanoma tumors in the brain may be worse?

Study quantifies hepatic and intestinal mRNA expression of Ugt isoforms in rats

Researchers identify multiple genetic variants associated with body fat distribution

High-protein and low-calorie diet helps older adults lose weight safely, shows study

HDL proteome behaves like a tiny Velcro ball that is rolling on surfaces

Study investigates the role of estrogen in controlling glucose homeostasis

Microbiologists identify enzyme that makes Helicobacter so adaptable

Low-calorie meals have protective effect against some diseases, reveals research

Researchers examine link between OSA and inflammation, organ damage

Lactate activates multiple genes that modulate neuronal activity

Newly discovered genetic disorder opens way for future diabetes drugs

Cancer-promoting changes seen in lung cells soon after exposure to low-molecular weight PAHs

Protein released from fat in response to exercise improves health

Targeting aging process itself can lead to better and more effective interventions

Alzheimer's disease protection from exercise hormone irisin

Study reveals how exercise may protect against Alzheimer's disease

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging