Metabolism News and Research

Latest Metabolism News and Research

Crtc switch activated during fasting helps halt spread of intestinal bacteria into bloodstream

A molecular pathway that is activated in the brain during fasting helps halt the spread of intestinal bacteria into the bloodstream, according to a new study by a team of researchers at the Salk Institute.

18 May 2016

Exercise may help reduce toxicity caused by glutamate build-up in the brain

In a new study published today in Applied Physiology, Nutrition, and Metabolism, scientists from the University of Guelph have found that exercise has the potential to decrease toxic build-up in the brain, reducing the severity of brain disorders such as Huntington's disease.

17 May 2016

Exercise plays significant role in combating obesity

Two factors—metabolism and gut microbes - have been credited by researchers as key players in the fight against obesity.

17 May 2016

New study links altered purine metabolism to major depressive disorder

People suffering from major depressive disorder may have altered purine metabolism, according to a new study from the University of Eastern Finland and Kuopio University Hospital.

17 May 2016

Researchers reveal new mechanism that helps breast cancer cells engage MDSCs

Not every breast cancer tumor follows the same path to grow. Some tumors have the assistance of myeloid-derived suppressor cells (MDSCs), a diverse type of immune cell involved in the suppression of the body's response against tumors.

17 May 2016

Sleep hormone melatonin may be responsible for type 2 diabetes risk among overnight workers

A new experimental and clinical study from Lund University in Sweden shows that the sleep hormone melatonin impairs insulin secretion in people with a common gene variant.

13 May 2016

Gene therapy shows promise in treating glioblastoma

A team from the International School for Advanced Studies in Trieste has obtained very promising results by applying gene therapy to glioblastoma.

13 May 2016

McGill researchers discover brain cells that play key role in leptin sensing, weight gain

It's rare for scientists to get what they describe as "clean" results without spending a lot of time repeating the same experiment over and over again. But when researchers saw the mice they were working with doubling their weight within a month or two, they knew they were on to something.

13 May 2016

Researchers produce insulin-secreting cells from stem cells of diabetic patients

Signaling a potential new approach to treating diabetes, researchers at Washington University School of Medicine in St. Louis and Harvard University have produced insulin-secreting cells from stem cells derived from patients with type 1 diabetes.

11 May 2016

Human gut model HuMiX represents actual conditions, processes that occur within intestines

One of the most complex human organs is the digestive tract: Here, the body comes into contact with all manner of diet-derived compounds and with countless bacteria.

11 May 2016

Oral regimens could offer simple solution for severe hyperglycaemia

Study findings indicate that oral treatments could offer a simpler alternative to upfront insulin for patients who have severe hyperglycaemia at the time of diagnosis with Type 2 diabetes.

10 May 2016

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed.

10 May 2016

Videogame addiction may impact sleep habits, obesity and cardio-metabolic health among children and teens

Some children and youth with high videogame addiction tendencies may be at risk of sleep deprivation and disorders associated with obesity and poor cardio-metabolic health, Hamilton researchers have found.

10 May 2016

Food deprivation may help treat fatty liver disease

Scientists at Helmholtz Zentrum München have new information on what happens at the molecular level when we go hungry. Working with the Deutsches Zentrum für Diabetesforschung and the Deutsches Krebsforschungszentrum they were able to show that upon deprivation of food a certain protein is produced that adjusts the metabolism in the liver.

9 May 2016

Cancerous lung tumors can alter metabolism by hijacking circadian mechanisms

University of California, Irvine scientists who study how circadian rhythms - our own body clocks - control liver function have discovered that cancerous lung tumors can hijack this process and profoundly alter metabolism.

6 May 2016

Studies show mango consumption may contribute to protective health effects

Four new studies surrounding the effects of mango consumption suggest this superfruit has the potential to help combat adverse effects associated with high fat diets and obesity (animal study), as well inhibit growth of fat cells (anti-lipogenic properties in an in-vivo study), slow advancement of breast cancer tumors (animal study), as well as improve regularity and decrease inflammation associated with constipation (human subject study).

6 May 2016

Development of atherosclerosis can increase osteoporosis risk

Patients with atherosclerosis—the buildup of cholesterol and fat in arteries—are at a higher risk of osteoporosis. A new study published in the American Journal of Physiology—Endocrinology and Metabolism shows how the development of atherosclerosis encourages the loss of bone density.

6 May 2016