Metabolism News and Research

Latest Metabolism News and Research

Review provides new insights into diagnosis, treatment for PCOS

Polycystic ovary syndrome (PCOS) afflicts over 14 million women in the United States. The disorder increases the risk of endometrial cancer, heart disease, high blood pressure, type 2 diabetes, asthma, obesity, depression and anxiety, as well as infertility and a variety of reproductive disorders.

4 Aug 2016

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients.

4 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

The microenvironment that supports a cancerous tumor also starves the immune cells that the body sends in to destroy the cancer, University of Pittsburgh Cancer Institute scientists revealed in a discovery that holds the potential to significantly boost the performance of breakthrough immunotherapy drugs.

2 Aug 2016

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

Paternal intake of a high-fat diet (HFD) can cause genetic changes that lead to generational obesity and metabolic dysfunction—including body weight and fat mass increases and changes in blood pressure, triglyceride levels and fat metabolism—in mice, according to Japanese researchers at Okayama University.

2 Aug 2016

New framework may help health professionals better understand, manage complexities of obesity

Existing models for measuring health impacts of the human diet are limiting our capacity to solve obesity and its related health problems, claim two of the world's leading nutritional scientists in their newest research.

1 Aug 2016

Diet rich in saturated fat reduces person's cognitive function making it difficult to control eating habits

A diet high in saturated fat can make your brain struggle to control what you eat, says a new study in Frontiers in Cellular Neuroscience.

29 Jul 2016

Study verifies human gene therapy in MPS I animal model

Researchers are closer to finding a better way to treat children with a rare metabolic disorder called MPS I. It is caused by a deficiency of the key enzyme IDUA needed to break down complex sugars in cells.

29 Jul 2016

Scientists develop photosensitive mimics of class of signaling molecules

Teams at Ludwig-Maximilians-Universitaet in Munich and EMBL have created photosensitive mimics of a class of signaling molecules, thus enabling their actions to be regulated by light, and affording new insights into the communications networks that control cellular metabolism.

29 Jul 2016

Majority of American adults use prescription drugs inappropriately and dangerously

The majority of American adults taking opioids and other commonly prescribed medications use them in ways that put their health at risk, including potentially dangerous combinations with other drugs, according to a new study from Quest Diagnostics, the world’s leading provider of diagnostic information services.

From Quest Diagnostics 29 Jul 2016

Scientists identify novel way to target lung cancer through KRAS gene

UT Southwestern Medical Center researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully.

29 Jul 2016

Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.

29 Jul 2016

Human immune system proteins can help combat chlamydia infections

Scientists from Federal Research and Clinical Centre of Physical-Chemical Medicine, Koltzov Institute of Developmental Biology and MIPT have shown that peptidoglycan recognition proteins (PGLYRPs) of the human immune system can play a key role in the fight against chlamydia infections. Their study was published in Infection and Immunity.

28 Jul 2016

Researchers develop new approach for visualizing oxygen in tissue

Learning how to look inside a body without having to cut it open is still an important part of medical research. One of the great challenges in imaging remains the visualization of oxygen in tissue.

28 Jul 2016

Maternal HIV infection could alter gut microbiome of HIV-exposed, uninfected infants

A study led by researchers at The Saban Research Institute of Children's Hospital Los Angeles suggests that maternal HIV infection influences the microbiome of their HIV-uninfected infants.

28 Jul 2016

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

In addition to its more obvious ills, type 2 diabetes is a condition closely associated with bone fractures, increasing the risk of fractures twofold. To make matters worse, certain anti-diabetic drugs further increase this risk, particularly in postmenopausal women, severely limiting their treatment options.

28 Jul 2016

Levels of peptide hormone adropin linked to carbohydrate intake

In research featured in the August edition of Obesity, Saint Louis University investigator Andrew Butler, Ph.D., and his team report that levels of the peptide hormone adropin vary based on carbohydrate consumption and appear to be linked to lipid metabolism.

27 Jul 2016

Researchers test new approach to treat metabolic diseases without organ transplant

With a shortage of donor organs, Mayo Clinic is exploring therapeutic strategies for patients with debilitating liver diseases. Researchers are testing a new approach to correct metabolic disorders without a whole organ transplant. Their findings appear in Science Translational Medicine.

27 Jul 2016

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

A drink developed for soldiers to generate energy from ketones rather than carbs or fat allowed highly trained cyclists to add up to 400 meters of distance to their workouts, a UK-led study reports July 27 in Cell Metabolism.

27 Jul 2016

Early and late menopause linked to increased risk of developing type 2 diabetes

Women who begin menopause before age 46 or after 55 have an increased risk of developing type 2 diabetes, according to a study of more than 124,000 women enrolled in the Women's Health Initiative, a large national trial aimed at preventing disease in postmenopausal women.

27 Jul 2016

Metabolism News and Research

Latest Metabolism News and Research

Review provides new insights into diagnosis, treatment for PCOS

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

New framework may help health professionals better understand, manage complexities of obesity

Diet rich in saturated fat reduces person's cognitive function making it difficult to control eating habits

Study verifies human gene therapy in MPS I animal model

Scientists develop photosensitive mimics of class of signaling molecules

Majority of American adults use prescription drugs inappropriately and dangerously

Scientists identify novel way to target lung cancer through KRAS gene

Blood pressure hormone system important for cardiovascular health can promote obesity

Human immune system proteins can help combat chlamydia infections

Researchers develop new approach for visualizing oxygen in tissue

Maternal HIV infection could alter gut microbiome of HIV-exposed, uninfected infants

TSRI scientists develop new dual-targeting drug candidate for treating diabetes and bone disease

Levels of peptide hormone adropin linked to carbohydrate intake

Researchers test new approach to treat metabolic diseases without organ transplant

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

Early and late menopause linked to increased risk of developing type 2 diabetes

Innovation in neuroscience drug discovery - eBook eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation