Metabolism News and Research

Latest Metabolism News and Research

MGH researchers develop new approach to skin rejuvenation

A new approach to skin rejuvenation developed at Massachusetts General Hospital (MGH) may be less likely to have unintended side effects such as scarring and altered pigmentation.

18 Jun 2015

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

'Walk through any supermarket and take a look at the labels on food products, and you'll see that many of them contain fructose, often in the form of sucrose (table sugar)' -- that's how Wilhelm Krek, professor for cell biology at ETH Zurich's Institute for Molecular Health Sciences, summarises the problem with today's nutrition.

18 Jun 2015

AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

AstraZeneca today announced a three-year research collaboration with the French National Institute of Health and Medical Research (Inserm) to investigate new therapeutic approaches totype 2 diabetes and Chronic Kidney Disease.

18 Jun 2015

Rare form of autoimmune syndrome may be tied to mutations in AIRE gene

A hereditary autoimmune disease that was thought to be exceedingly rare may have a less severe form that affects one in 1,000 people or even more, according to new research conducted at the Weizmann Institute of Science, in Israel, and the University of Bergen, in Norway.

18 Jun 2015

AMRI, PerkinElmer form strategic collaboration to accelerate drug discovery

As further evidence of Governor Andrew M. Cuomo's successful establishment of a dynamic and growing bio-pharma sector in Buffalo, New York, Albany Molecular Research Inc. and PerkinElmer, Inc. today announced the formation of a strategic collaboration in connection with the opening of AMRI's drug discovery center as part of the new Buffalo Medical Innovation and Commercialization Hub.

17 Jun 2015

La Jolla Institute researchers identify molecular pathway that maintains Treg cells' function

Regulatory T cells (Treg cells) are part of the system of checks and balances that prevents the immune response from going overboard and causing autoimmune disease. Although critically important for shaping the immune response and maintaining self-tolerance, how they hold on to their immune-suppressive powers had remained unclear.

17 Jun 2015

Rapamycin drug reduces obesity, preserves lean body mass in older rats

Aging can cause many changes to the body, including obesity and a loss of lean mass. Now, a group of University of Florida Health researchers has discovered that an existing drug reduces body fat and appetite in older rats, which has intriguing implications for aging humans.

17 Jun 2015

MGH-CEM researchers develop novel approach to evaluate the liver's drug-metabolizing activity

A team of researchers from the Massachusetts General Hospital Center for Engineering in Medicine (MGH-CEM) has developed a novel approach that dramatically simplifies the evaluation of the liver's drug-metabolizing activity and the potential toxic effects of the products of that activity on other organs.

17 Jun 2015

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

Since the 2009 discovery that energy-burning brown fat can be active in adults, research has raced ahead to understand this tissue and exploit it to treat the epidemic of obesity. Active brown fat also may assist in directly easing the burden of diabetes and related metabolic diseases by lowering the levels of glucose and fatty acids in the bloodstream. But progress in studying human brown fat often has been slowed by difficulties in obtaining and studying samples of the human cells that develop into brown fat.

17 Jun 2015

Fruit flies helping FAU researchers to discover novel genes responsible for neuroprotection

They're pesky and annoying when they get into your fruit, but Drosophila melanogaster, more affectionately known as the "fruit fly," are helping researchers at Florida Atlantic University to discover novel genes that are responsible for neuroprotection.

17 Jun 2015

New review outlines basic principles of dietary treatment

Thanks to screening of newborns and newly developed therapies, the population of patients with inherited metabolic disorders has expanded. As these patients age and enter adulthood, diet therapy will be the mainstay of treatment for their disorders.

16 Jun 2015

Scientists report that mouse with weak bones appears to have strong metabolism

One mouse with weak bones appears to have a strong metabolism, even on a high-fat diet, scientists report. While weaker bones are clearly not a good thing, scientists suspect that, somewhere in the conversation between the genetically engineered mouse's skeleton and the rest of its body, there may be an answer that helps obese individuals avoid some of the worst ravages of this health epidemic.

16 Jun 2015

NTCELL Phase I/IIa clinical study meets primary endpoint in patients with Parkinson’s disease

Living Cell Technologies Limited today announced results from a Phase I/IIa clinical study of NTCELL, an experimental regenerative cell therapy being studied as a disease-modifying agent in Parkinson’s disease. The study, conducted in four patients in New Zealand, met its primary endpoint of safety, showing NTCELL implantation was well tolerated, with no adverse events considered to be related to NTCELL.

15 Jun 2015

New therapy for osteoporosis may be in the pipeline

Researchers from The Scripps Research Institute (TSRI), Florida, have reported a novel therapeutic approach that could promote the formation of new bone cells in people suffering from bone loss.

12 Jun 2015

Adding high salt to high-fat diet prevents weight gain in mice

In a study that seems to defy conventional dietary wisdom, University of Iowa scientists have found that adding high salt to a high-fat diet actually prevents weight gain in mice.

11 Jun 2015

Study reveals new information about role of abdominal fat in teens with CAH

Researchers at Children's Hospital Los Angeles have demonstrated that adolescents and young adults with congenital adrenal hyperplasia (CAH) have significantly increased amounts of abdominal fat tissue, placing them at greater risk for harmful conditions linked to obesity, including cardiovascular disease (CVD).

11 Jun 2015

Physical activities may not protect against underlying markers for Alzheimer's disease

While participating in physical activities such as bike riding, dancing, walking and gardening and mentally stimulating activities such as crosswords and reading may reduce the risk of Alzheimer's disease, they may not do so by affecting the underlying markers for the disease, according to a study published in the June 10, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology.

11 Jun 2015

Paediatric outpatient study compares effectiveness of three alternative treatments for type 1 diabetes

A Montréal research team, co-supervised by Dr. Rémi Rabasa-Lhoret from the IRCM and Dr. Laurent Legault from the Montreal Children's Hospital, undertook the first paediatric outpatient study to compare three alternative treatments for type 1 diabetes.

11 Jun 2015

Credentialed health care professionals have greater knowledge of evidence-based nutrition support practice

Multidisciplinary health care professionals who hold the Certified Nutrition Support Credential (CNSC) scored significantly higher on a survey about their approaches to nutrition support practice than those who do not hold the credential according to new study.

11 Jun 2015

Treating obesity with GLP-1 hormone helps prevent loss of bone mass associated with weight loss

Using the intestinal hormone GLP-1 in obesity treatment prevents the loss of bone mass otherwise frequently associated with major weight loss. This is the finding of a new study from the University of Copenhagen, Hvidovre and Glostrup Hospital. According to the researchers behind the study, the results may have a significant bearing on future obesity treatment.

11 Jun 2015

Metabolism News and Research

Latest Metabolism News and Research

MGH researchers develop new approach to skin rejuvenation

High fructose consumption can lead to uncontrolled growth of cardiomyocytes, heart attack

AstraZeneca, Inserm to investigate new therapeutic approaches to type 2 diabetes, CKD

Rare form of autoimmune syndrome may be tied to mutations in AIRE gene

AMRI, PerkinElmer form strategic collaboration to accelerate drug discovery

La Jolla Institute researchers identify molecular pathway that maintains Treg cells' function

Rapamycin drug reduces obesity, preserves lean body mass in older rats

MGH-CEM researchers develop novel approach to evaluate the liver's drug-metabolizing activity

Researchers create cell lines to study gene expression in precursor brown fat and white fat cells

Fruit flies helping FAU researchers to discover novel genes responsible for neuroprotection

New review outlines basic principles of dietary treatment

Scientists report that mouse with weak bones appears to have strong metabolism

NTCELL Phase I/IIa clinical study meets primary endpoint in patients with Parkinson’s disease

New therapy for osteoporosis may be in the pipeline

Adding high salt to high-fat diet prevents weight gain in mice

Study reveals new information about role of abdominal fat in teens with CAH

Physical activities may not protect against underlying markers for Alzheimer's disease

Paediatric outpatient study compares effectiveness of three alternative treatments for type 1 diabetes

Credentialed health care professionals have greater knowledge of evidence-based nutrition support practice

Treating obesity with GLP-1 hormone helps prevent loss of bone mass associated with weight loss

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation