Metabolism News and Research

Latest Metabolism News and Research

RNA interference identifies function of genes linked with cardiovascular disease

Studies screening the genome of hundreds of thousands of individuals (known as Genome-wide association studies or GWAS) have linked more than 100 regions in the genome to the risk of developing cardiovascular disease.

1 Mar 2013

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

Promethera Biosciences, a Belgian biotechnology company developing Promethera(R) HepaStem, a cell-based therapy for the treatment of liver-based metabolic diseases including Crigler-Najjar Syndrome and Urea Cycle Disorders, announced that it has successfully treated a patient with liver progenitor cells enrolled in its Phase I/II trial.

1 Mar 2013

UMDNJ biochemist to research into mechanisms that control gene expression in mitochondria

Dmitry Temiakov, PhD, a biochemist at the University of Medicine and Dentistry of New Jersey-School of Osteopathic Medicine, has received a five-year, $1.5 million grant from the National Institutes of Health (NIH) to fund research into the molecular mechanisms that control gene expression in mitochondria, the organelles that are the "power plants" of cellular activity.

1 Mar 2013

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

New research published today in the Biochemical Journal describes the discovery of a new cancer target.

28 Feb 2013

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Researchers at the University of Michigan School of Kinesiology have received a $1 million grant to study how exercise and other therapies might work differently in lean and obese individuals.

28 Feb 2013

Study indicates how gastric bypass reverses diabetes

In a substudy of the STAMPEDE trial (Surgical Therapy And Medications Potentially Eradicate Diabetes Efficiently), Cleveland Clinic researchers have found that gastric bypass surgery reverses diabetes by uniquely restoring pancreatic function in moderately obese patients with uncontrolled type 2 diabetes.

28 Feb 2013

Newborn screening improves detection of lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys

Contrary to current belief, routine newborn screening improves the detection of the lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys, saving lives in both sexes, according to a unique study of CAH during the last 100 years published Online First in The Lancet Diabetes and Endocrinology.

27 Feb 2013

Princeton metabolic model can predict how parasites would fare in altered climates

Knowing the temperatures that viruses, bacteria, worms and all other parasites need to grow and survive could help determine the future range of infectious diseases under climate change, according to new research.

27 Feb 2013

Wnt-induced Lgr5 expression marks stem cell production in the liver

For decades scientists around the world have attempted to regenerate primary liver cells known as hepatocytes because of their numerous biomedical applications, including hepatitis research, drug metabolism and toxicity studies, as well as transplantation for cirrhosis and other chronic liver conditions. But no lab in the world has been successful in identifying and growing liver stem cells in culture -- using any available technique - until now.

26 Feb 2013

Early lymphoid progenitors thrive in an osteoblastic niche: Study

The Children's Medical Center Research Institute at UT Southwestern has deepened the understanding of the environment within bone marrow that nurtures stem cells, this time identifying the biological setting for specialized blood-forming cells that produce the infection-fighting white blood cells known as T cells and B cells.

25 Feb 2013

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

The University of Colorado (CU) has signed exclusive, worldwide licensing and collaboration agreements with rare-disease research-and-development firm Orphan Technologies Ltd to develop an enzyme replacement therapy for Cystathionine Beta-Synthase (CBS) -deficient homocystinuria, a rare, inherited metabolic disease that is often fatal at a young age.

25 Feb 2013

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Researchers at the University of Wisconsin-Madison have found a new way to accelerate a workhorse instrument that identifies proteins. The high-speed technique could help diagnose cancer sooner and point to new drugs for treating a wide range of conditions.

25 Feb 2013

Study shows how hyperparathyroidism affects people of different racial backgrounds

Unusually high calcium levels in the blood can almost always be traced to primary hyperparathyroidism, an undertreated, underreported condition that affects mainly women and the elderly, according to a new study by UCLA researchers.

22 Feb 2013

Disruption in the body's circadian rhythm can increase risk of diabetes, heart disease

Disruption in the body's circadian rhythm can lead not only to obesity, but can also increase the risk of diabetes and heart disease.

22 Feb 2013

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Research conducted by Dr. Jayne S. Weiss, Professor and Chair of Ophthalmology at LSU Health Sciences Center New Orleans, and colleagues has discovered a new mutation in a gene that causes Schnyder corneal dystrophy (SCD.)

22 Feb 2013

Viewpoints: Holtz-Eakin and Roy offer prescription to fix health law; Iowa lawmakers opposed to Medicaid expansion should give up their coverage

Over nearly a century, progressives have pressed for a national, single-payer healthcare system. When it comes to health reform, what have conservatives stood for? For far too long, conservatives have failed to coalesce around a long-term vision of what a free-market healthcare system should look like. ... Obamacare is the logical byproduct of this conservative policy neglect.

22 Feb 2013

Omega-3 emulsions can decrease brain tissue damage following stroke

Triglyceride lipid emulsions rich in an omega-3 fatty acid injected within a few hours of an ischemic stroke can decrease the amount of damaged brain tissue by 50 percent or more in mice, reports a new study by researchers at Columbia University Medical Center.

21 Feb 2013

U.N. report examines links between man-made chemicals, health issues

"Man-made chemicals in everyday products are likely to be at least the partial cause of a global surge in birth deformities, hormonal cancers and psychiatric diseases, a U.N.-sponsored research team reported on Tuesday," Reuters reports.

21 Feb 2013

Sleep-deprived people select greater portion sizes of energy-dense snacks and meals

New research from Uppsala University shows that sleep-deprived people select greater portion sizes of energy-dense snacks and meals than they do after one night of normal sleep. Poor sleep habits can therefore affect people's risk of becoming overweight in the long run. The findings are published in Psychoneuroendocrinology.

20 Feb 2013

Study determines frequency of genetic variants linked to alcoholism for Spanish population

Research done at the UPV/EHU-University of the Basque Country has determined the frequency of genetic variants linked to alcoholism for the Spanish population, and its incidence not only in individuals with a high level of alcohol intake, but also in individuals with alcohol dependence.

20 Feb 2013

Metabolism News and Research

Latest Metabolism News and Research

RNA interference identifies function of genes linked with cardiovascular disease

Urea cycle disorder patient successfully treated by Promethera(R) HepaStem in Phase I/II trial in France

UMDNJ biochemist to research into mechanisms that control gene expression in mitochondria

Researchers discover unrecognized mechanism by which PI3K sustains proliferation of cancer cells

U-M to study how exercise, other therapies might work differently in lean and obese individuals

Study indicates how gastric bypass reverses diabetes

Newborn screening improves detection of lethal form of congenital adrenal hyperplasia (CAH) in girls as well as boys

Princeton metabolic model can predict how parasites would fare in altered climates

Wnt-induced Lgr5 expression marks stem cell production in the liver

Early lymphoid progenitors thrive in an osteoblastic niche: Study

Orphan, CU to develop enzyme replacement therapy for CBS-deficient homocystinuria

Researchers discover new way to accelerate mass spectrometer that identifies proteins

Study shows how hyperparathyroidism affects people of different racial backgrounds

Disruption in the body's circadian rhythm can increase risk of diabetes, heart disease

Study finds new mutation in UBIAD1 gene that causes Schnyder corneal dystrophy

Viewpoints: Holtz-Eakin and Roy offer prescription to fix health law; Iowa lawmakers opposed to Medicaid expansion should give up their coverage

Omega-3 emulsions can decrease brain tissue damage following stroke

U.N. report examines links between man-made chemicals, health issues

Sleep-deprived people select greater portion sizes of energy-dense snacks and meals

Study determines frequency of genetic variants linked to alcoholism for Spanish population

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CellVoyant's AI-Powered Vision for the Future of Cell Therapy