Metabolism News and Research

Latest Metabolism News and Research

Life-prolonging effect of vitamin niacin demonstrated in roundworms

Who would not want to live a long and healthy life? A freely available food supplement could help in this respect, scientists from ETH Zurich have demonstrated in roundworms. Vitamin B3 - also known as niacin - and its metabolite nicotinamide in the worms' diet caused them to live for about one tenth longer than usual.

1 Oct 2013

Study shows direct causative link between obesity and risk of pancreatic cancer in mice

Researchers at UCLA's Jonsson Comprehensive Cancer Center (JCCC) have found that mice made obese by being given high-calorie, high-fat diets (HFCD) developed abnormally high numbers of lesions known as pancreatic intraepithelial neoplasias (PanINs), which are known to be precursors to pancreas cancer.

1 Oct 2013

Diabetic patients at greater risk of breast, colon cancer

Diabetes is linked to an increased risk of developing cancer, and now researchers have performed a unique meta-analysis that excludes all other causes of death and found that diabetic patients not only have an increased risk of developing breast and colon cancer but an even higher risk of dying from them.

30 Sep 2013

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

The first Phase II study to investigate the use of the anti-cancer drug, everolimus, for the initial treatment of advanced papillary kidney cancer has shown that it is successful in slowing or preventing the spread of the disease, according to research to be presented today (Sunday) at the 2013 European Cancer Congress.

29 Sep 2013

Researchers discover severe health consequences of folic acid deficiency

Researchers from the universities of Calgary and Cambridge, UK, have discovered that a mutation in a gene necessary for the metabolism of folic acid not only impacts immediate offspring but can also have detrimental health effects, such as spina bifida and heart abnormalities, on subsequent generations.

29 Sep 2013

NIH program provides $22M for low- and middle-income countries to combat HIV/AIDS epidemic

A new NIH program supporting HIV-related research training will provide $22 million over five years for activities in 15 low- and middle-income countries. The Fogarty International Center's HIV Research Training Program is issuing 22 awards, which are intended to strengthen the ability of the grantee institutions to combat the HIV/AIDS epidemic, while building expertise in a particular scientific or critical research infrastructure area.

27 Sep 2013

Mayo Clinic experts to discuss risk factors, screening and treatments for breast cancer

October is National Breast Cancer Awareness Month, and Mayo Clinic breast cancer experts are available to discuss risk factors, screening and treatments.

27 Sep 2013

Folic acid deficiency may be associated with multi-generational impact on health

Folic acid deficiency can cause severe health problems in offspring, including spina bifida, heart defects and placental abnormalities. A study out today reveals that a mutation in a gene necessary for the metabolism of folic acid not only impacts the immediate offspring but can also have detrimental health effects on the next several generations.

27 Sep 2013

Study on tempol impacted gut bacteria may lead to new treatments for obesity

A drug that appears to target specific intestinal bacteria in the guts of mice may create a chain reaction that could eventually lead to new treatments for obesity and diabetes in humans, according to a team of researchers.

25 Sep 2013

Cerebral imaging in patients with early symptoms of AD may have better clinical outcomes

Patients suffering from early symptoms of Alzheimer's disease who were diagnosed sooner than usual using a brain imaging test received Alzheimer-specific medications earlier than those who did not have the brain imaging results available to their doctors or themselves.

25 Sep 2013

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Rhythm announced today the initiation of the first of a series of clinical trials with RM-493, the company's novel melanocortin 4 receptor (MC4R) agonist, for the treatment of obesity in individuals with a genetic deficiency in the MC4R pathway.

24 Sep 2013

Mayo Clinic expands genomic research by establishing biobank at Arizona campus

Mayo Clinic has again broadened the base of its genomic research efforts by establishing a biobank at its Arizona campus, which will support studies in obesity, metabolism and diabetes, all areas of special concern in the Latino population.

24 Sep 2013

Understanding genetic, physiological basis for metabolic diseases related to circadian function

A new study by a team of University of Notre Dame researchers, which appears in the Sept. 2 edition of the journal PLoS ONE, is a significant step in understanding the molecular genetic and physiological basis for a spectrum of metabolic diseases related to circadian function.

24 Sep 2013

Researchers discover drug that halts growth of brain tumor cells

Working with mice, Johns Hopkins researchers have discovered that weeks of treatment with a repurposed FDA-approved drug halted the growth of - and ultimately left no detectable trace of - brain tumor cells taken from adult human patients.

24 Sep 2013

Humans consuming artificial sweetener are likely to choose high calorie alternatives in future

The results of the new study imply that it is hard to fool the brain by providing it with 'energyless' sweet flavours.

23 Sep 2013

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

In the course of life, aging processes, environmental influences and lifestyle factors such as smoking or diet induce biochemical alterations to the DNA. Frequently, these lead to DNA methylation, a process in which methyl groups are added to particular DNA segments, without changing the DNA sequence.

21 Sep 2013

EDCs pose threat to human health, say endocrine experts

In an editorial published in Endocrinology, a journal of The Endocrine Society, endocrine experts agreed that endocrine-disrupting chemicals pose a threat to human health and to the ecosystems of the earth.

20 Sep 2013

New islet transplantation improves results for patients with type 1 diabetes

The latest approach to islet transplantation, in which clusters of insulin-producing cells known as islets are transplanted from a donor pancreas into another person's liver, has produced substantially improved results for patients with type 1 diabetes, and may offer a more durable alternative to a whole pancreas transplant.

20 Sep 2013

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Over the last decade researchers have amassed increasing evidence that relatively low levels of a protein called sex hormone binding globulin (SHBG) can indicate an elevated risk of type 2 diabetes and metabolic syndrome years in advance.

19 Sep 2013

Mayo Clinic receives grant from NIH to support medical research on metabolomics

Mayo Clinic is one of six new federally-funded Comprehensive Metabolomics (met-ah-bol-OH-mics) Centers to support medical research on metabolomics -- the study, at the cellular level, of how molecules are metabolized in the body.

19 Sep 2013

Metabolism News and Research

Latest Metabolism News and Research

Life-prolonging effect of vitamin niacin demonstrated in roundworms

Study shows direct causative link between obesity and risk of pancreatic cancer in mice

Diabetic patients at greater risk of breast, colon cancer

First Phase II study: Everolimus drug slows spread of advanced papillary kidney cancer

Researchers discover severe health consequences of folic acid deficiency

NIH program provides $22M for low- and middle-income countries to combat HIV/AIDS epidemic

Mayo Clinic experts to discuss risk factors, screening and treatments for breast cancer

Folic acid deficiency may be associated with multi-generational impact on health

Study on tempol impacted gut bacteria may lead to new treatments for obesity

Cerebral imaging in patients with early symptoms of AD may have better clinical outcomes

Rhythm starts RM-493 clinical trials in obesity patients with genetic deficiency

Mayo Clinic expands genomic research by establishing biobank at Arizona campus

Understanding genetic, physiological basis for metabolic diseases related to circadian function

Researchers discover drug that halts growth of brain tumor cells

Humans consuming artificial sweetener are likely to choose high calorie alternatives in future

Study shows how lifestyle factors can influence metabolism via resulting alterations in DNA

EDCs pose threat to human health, say endocrine experts

New islet transplantation improves results for patients with type 1 diabetes

SHBG protein indicates risk of type 2 diabetes and metabolic syndrome years in advance

Mayo Clinic receives grant from NIH to support medical research on metabolomics

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