Metabolism News and Research

Latest Metabolism News and Research

GCC hormone receptor may also help fight obesity

The hormone receptor guanylyl cyclase C (GCC) has been established as a suppressor of colorectal cancer tumors, but new evidence from Thomas Jefferson University suggests it may also help fight one of the country's biggest pandemics: obesity.

26 Aug 2011

Researchers pave the way for functional analysis of non-protein-coding genes

When investigating cancer cells, researchers discovered numerous peculiarities: Particular RNA molecules are present in large numbers, particular genes are overactive. Do these characteristics have a relation to cancer? Do they promote cell growth? Do they inactivate growth brakes or are they just a whim of nature?

25 Aug 2011

Hearing dietary advice twice is enough for patients to get benefits of lower cholesterol

Hearing dietary advice twice is enough for patients to get the significant benefits of lower cholesterol, according to a new study led by doctors at St. Michael's Hospital and the University of Toronto.

25 Aug 2011

Study finds biological indicators that help explain why obese people develop chronic diseases

UC Davis Health System researchers have discovered biological indicators that help explain why some obese people develop chronic diseases such as diabetes and heart disease, and others do not.

25 Aug 2011

AMT total net loss decreases 7% to € 8.7 million for first half year of 2011

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, today reported its results for the first half year of 2011.

25 Aug 2011

Scientists identify critical protein responsible for Ebola virus infection

In separate papers published online in Nature, two research teams report identifying a critical protein that Ebola virus exploits to cause deadly infections. The protein target is an essential element through which the virus enters living cells to cause disease.

25 Aug 2011

Insight into acrolein-induced acute lung injury

Metabolon, Inc., the leader in metabolomics, biomarker discovery and biochemical analysis, announces the publication of "Integrative Metabolome and Transcriptome Profiling Reveals Discordant Energetic Stress Between Mouse Strains with Differential Sensitivity to Acrolein-Induced Acute Lung Injury" in The Molecular Nutrition and Food Research Journal.

24 Aug 2011

Roche Canada grants Vasculitis and Scleroderma Fellowship

Roche Canada announced today its support of a Vasculitis and Scleroderma Fellowship through the Division of Rheumatology at the University of British Columbia (UBC). Dr. Ada Man, a recent graduate of the UBC rheumatology residency program, is the recipient of the one-year Fellowship.

23 Aug 2011

Researchers show that Sirt3 enzyme decreases in skeletal muscle of diabetes patients

Researchers at the Joslin Diabetes Center have shown that an enzyme found in the mitochondria of cells is decreased in the skeletal muscle of those with diabetes, a finding that could lead to the development of drugs to boost the activity of this enzyme in an effort to fight the disease.

23 Aug 2011

Helsinn begins enrollment in anamorelin Phase III trial for NSCLC-associated anorexia/cachexia

Helsinn, a Swiss-based pharmaceutical company, announced today that its US subsidiary, Helsinn Therapeutics, has enrolled the first patient in the company's pivotal Phase III clinical program of anamorelin HCl for the treatment of anorexia/cachexia in patients with advanced non-small cell lung cancer.

23 Aug 2011

Saffron promotes apoptosis and inhibits growth of cancerous cells

New research suggests that saffron provides a significant chemopreventive effect against liver cancer in animal models. When saffron was administered to rats with diethylnitrosamine (DEN)-induced liver cancer an inhibition of cell proliferation and stimulation of apoptosis was observed. Full findings appear in the September issue of Hepatology, a journal published by Wiley Blackwell on behalf of the American Association for the Study of Liver Diseases.

22 Aug 2011

ATGL produces key signaling molecules essential for regulation of lipid, energy metabolism

Obesity, diabetes, and cardiovascular diseases are daunting modern-day epidemics. In Western Europe more than 50% of the population is overweight and approximately 15 million people die from cardiovascular diseases such as heart attacks and stroke every year. These conditions are often caused by disorders of fat metabolism, resulting in a massive accumulation of fat in various tissues and of cholesterol in the walls of arteries.

22 Aug 2011

First computerized genome-scale model of cancer cell metabolism

Scientists are constantly on the hunt for treatments that can selectively target cancer cells, leaving other cells in our bodies unharmed.

22 Aug 2011

Two studies on how amino acids influence protein synthesis in recreational athletes

Physical activity requires strong, healthy muscles. Fortunately, when people exercise on a regular basis, their muscles experience a continuous cycle of muscle breakdown (during exercise) and compensatory remodeling and growth. Athletes have long experimented with methods to augment these physiologic responses to enhance muscle growth.

20 Aug 2011

New model for biomedical education

Leaders in biomedical education at Johns Hopkins University School of Medicine are calling for a radical new approach to post-graduate training in the life sciences to address significant challenges, including an avalanche of new discoveries in the last decade and the need to transcend traditional departmental boundaries to understand biological processes at multiple levels.

20 Aug 2011

Medicinal Genomics sequences entire genomes of two therapeutic Cannabis strains

Medicinal Genomics, a private company headquartered in Marblehead, Mass., USA and the Netherlands, announced today that it has sequenced the entire genomes of Cannabis sativa and Cannabis indica, representing two strains of the therapeutic plant.

19 Aug 2011

Conference to discuss latest research on gender disparities in cardiovascular disease

Heart disease has sometimes been considered a men's health issue, but the statistics prove otherwise. In the US alone, more than 42 million women live with the problem. Heart disease is responsible for more than one-third of deaths among American women each year, making it the number one killer of females older than 20.

19 Aug 2011

FDA grants Fast Track designation for DARA's KRN5500 neuropathic pain relief drug

DARA BioSciences, Inc. announced today that its investigational drug KRN5500 has been granted Fast Track designation by the U.S. Food and Drug Administration (FDA) for the treatment of chemotherapy-induced neuropathic pain in patients with cancer.

19 Aug 2011

Herbal supplements may weaken the effect of chemotherapy drugs

Acai berry, cumin, herbal tea, turmeric and long-term use of garlic - all herbal supplements commonly believed to be beneficial to your health - may negatively impact chemotherapy treatment according to a new report presented at the American Society of Clinical Oncology (ASCO) meeting in Chicago this summer.

18 Aug 2011

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Stem cell researchers at UCLA have discovered that three types of cells derived from human embryonic stem cells and induced pluripotent stem cells are similar to each other, but are much more developmentally immature than previously thought when compared to those same cell types taken directly from human tissue.

18 Aug 2011

Metabolism News and Research

Latest Metabolism News and Research

GCC hormone receptor may also help fight obesity

Researchers pave the way for functional analysis of non-protein-coding genes

Hearing dietary advice twice is enough for patients to get benefits of lower cholesterol

Study finds biological indicators that help explain why obese people develop chronic diseases

AMT total net loss decreases 7% to € 8.7 million for first half year of 2011

Scientists identify critical protein responsible for Ebola virus infection

Insight into acrolein-induced acute lung injury

Roche Canada grants Vasculitis and Scleroderma Fellowship

Researchers show that Sirt3 enzyme decreases in skeletal muscle of diabetes patients

Helsinn begins enrollment in anamorelin Phase III trial for NSCLC-associated anorexia/cachexia

Saffron promotes apoptosis and inhibits growth of cancerous cells

ATGL produces key signaling molecules essential for regulation of lipid, energy metabolism

First computerized genome-scale model of cancer cell metabolism

Two studies on how amino acids influence protein synthesis in recreational athletes

New model for biomedical education

Medicinal Genomics sequences entire genomes of two therapeutic Cannabis strains

Conference to discuss latest research on gender disparities in cardiovascular disease

FDA grants Fast Track designation for DARA's KRN5500 neuropathic pain relief drug

Herbal supplements may weaken the effect of chemotherapy drugs

Human embryonic stem cell, iPS-derived progeny are similar and developmentally immature

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech