Metabolism News and Research

Latest Metabolism News and Research

Male and female rats show different patterns of kidney gene expression throughout their lives

Male and female rats show different patterns of kidney gene expression throughout their lives, a study in the open access journal Biology of Sex Differences reveals. The finding could help explain some of the gender differences observed in human renal disease, and lead to improved biomarkers of kidney function.

31 Jul 2013

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Statins, a class of cholesterol-lowering drugs found in millions of medicine cabinets, may help treat Rett Syndrome, according to a study published today in Nature Genetics. The Rett Syndrome Research Trust (RSRT) funded this work with generous support from the Rett Syndrome Research Trust UK and Rett Syndrome Research & Treatment Foundation.

30 Jul 2013

Forest Laboratories, Pierre Fabre Laboratories announce that FETZIMA gets FDA approval for MDD

Forest Laboratories, Inc. and Pierre Fabre Laboratories announced today that FETZIMA (levomilnacipran extended-release capsules), a once-daily serotonin and norepinephrine reuptake inhibitor, discovered by Pierre Fabre Laboratories and co-developed by Forest Laboratories, Inc. was approved by the U.S. Food and Drug Administration for the treatment of Major Depressive Disorder in adults.

26 Jul 2013

Researchers explain how gut bacteria can inactivate cardiac drugs

For decades, doctors have understood that microbes in the human gut can influence how certain drugs work in the body - by either activating or inactivating specific compounds, but questions have long remained about exactly how the process works.

26 Jul 2013

New biosensor can alert athletes when they are about to bonk or hit the wall

A new biosensor, applied to the human skin like a temporary tattoo, can alert marathoners, competitive bikers and other "extreme" athletes that they're about to "bonk," or "hit the wall," scientists are reporting. The study, in ACS' journal Analytical Chemistry, describes the first human tests of the sensor, which also could help soldiers and others who engage in intense exercise - and their trainers - monitor stamina and fitness.

25 Jul 2013

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

NOXXON Pharma today announced the successful completion of patient recruitment of its NOX-E36 Phase IIa clinical trial for the treatment of diabetic nephropathy. NOX-E36 is a Spiegelmer® that binds and neutralizes CCL2/MCP-1 (C-C Chemokine Ligand / Monocyte Chemoattractant Protein-1), a pro-inflammatory chemokine that plays an important role in the progression of diabetic nephropathy, the most common single cause of chronic kidney failure and end-stage renal disease.

25 Jul 2013

GSD receives FDA Clearance for 25-OH Vitamin D Total ELISA test

Gold Standard Diagnostics, Corp., a leading manufacturer and marketer of clinical laboratory instrumentation and assays for the in vitro diagnostics market, announced 510k FDA Clearance of its 25-OH Vitamin D, Total ELISA.

24 Jul 2013

Female cancer patients unhappy with the way doctors discussed about fertility preservation options

Young female cancer patients are unhappy about the way fertility preservation options are discussed with them by doctors before starting cancer treatment, according to a new study by researchers from the University of Sheffield and The Children's Hospital, Sheffield.

23 Jul 2013

Cedars-Sinai investigator awarded grant to study cell metabolism in childhood sarcomas

Sandra Orsulic, PhD, director of Women's Cancer Biology in the Women's Cancer Program at the Cedars-Sinai Samuel Oschin Comprehensive Cancer Institute, was awarded a $250,000 grant from Alex's Lemonade Stand Foundation to study cell metabolism in childhood sarcomas.

22 Jul 2013

EU-funded project examines dietary habits in people with inadequate nutrition

Until now, we have had very little understanding of the extent of malnutrition in Europe, especially in populations at risk of poverty. Now, an EU-funded project calledCHANCE, aims to address the dietary habits in people with inadequate nutrition.

20 Jul 2013

UCSF researchers find a way to knock down cancers caused by tumor-driving protein

UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called -myc,- paving the way for patients with myc-driven cancers to enroll in clinical trials for experimental treatments.

20 Jul 2013

New research uncovers biological ties between obesity and asthma

Genes linked to chronic inflammation in asthma may be more active in people who are obese, according to new research that uncovers several biological ties between obesity and asthma.

19 Jul 2013

UCSF researchers find way to knock down cancers caused by myc protein

UC San Francisco researchers have found a way to knock down cancers caused by a tumor-driving protein called "myc," paving the way for patients with myc-driven cancers to enroll in clinical trials for experimental treatments.

19 Jul 2013

Metabolomics tools predict who can benefit from treatment with certain antidepressants

Duke Medicine researchers have identified biochemical changes in people taking antidepressants - but only in those whose depression improves. These changes occur in a neurotransmitter pathway that is connected to the pineal gland, the part of the endocrine system that controls the sleep cycle, suggesting an added link between sleep, depression and treatment outcomes.

19 Jul 2013

Researchers identify genetic cause of severe obesity

Researchers at Boston Children's Hospital have identified a genetic cause of severe obesity that, though rare, raises new questions about weight gain and energy use in the general obese population. The research, published in the journal Science on July 19, involved genetic surveys of several groups of obese humans and experiments in mice.

19 Jul 2013

HemoShear announces milestone in development of predictive drug safety systems

HemoShear, LLC, a leading developer of human-relevant systems for drug development and discovery, today announced an important milestone in the development of systems that predict safety of new drugs and chemicals.

19 Jul 2013

Engineered liver tissue developed at MIT could help scientists test new drugs, vaccines for malaria

Although malaria has been eradicated in many countries, including the United States, it still infects more than 200 million people worldwide, killing nearly a million every year. In regions where malaria is endemic, people rely on preventive measures such as mosquito netting and insecticides. Existing drugs can help, but the malaria parasite is becoming resistant to many of them.

18 Jul 2013

Vitamin D-deficient older individuals are more likely to struggle with everyday tasks

Chevy Chase, MD-Vitamin D-deficient older individuals are more likely to struggle with everyday tasks such as dressing or climbing stairs, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

18 Jul 2013

Exposure to PFC may increase risk of mild hypothyroidism in women

Exposure to perfluorinated chemicals is linked to changes in thyroid function and may raise the risk of mild hypothyroidism in women, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

18 Jul 2013

TAp73 protein frequently overexpressed in wide range of human tumors

They say you can pick your friends, but not your family. The same may hold true for related proteins. The protein TAp73 is a relative of the well-known, tumor-suppressor protein p53. It shares extensive common gene sequences with p53 and, as suggested by some previous studies, it may function similar to p53 to prevent tumor formation.

17 Jul 2013

Metabolism News and Research

Latest Metabolism News and Research

Male and female rats show different patterns of kidney gene expression throughout their lives

Statins: A class of cholesterol-lowering drugs may help treat Rett Syndrome

Forest Laboratories, Pierre Fabre Laboratories announce that FETZIMA gets FDA approval for MDD

Researchers explain how gut bacteria can inactivate cardiac drugs

New biosensor can alert athletes when they are about to bonk or hit the wall

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

GSD receives FDA Clearance for 25-OH Vitamin D Total ELISA test

Female cancer patients unhappy with the way doctors discussed about fertility preservation options

Cedars-Sinai investigator awarded grant to study cell metabolism in childhood sarcomas

EU-funded project examines dietary habits in people with inadequate nutrition

UCSF researchers find a way to knock down cancers caused by tumor-driving protein

New research uncovers biological ties between obesity and asthma

UCSF researchers find way to knock down cancers caused by myc protein

Metabolomics tools predict who can benefit from treatment with certain antidepressants

Researchers identify genetic cause of severe obesity

HemoShear announces milestone in development of predictive drug safety systems

Engineered liver tissue developed at MIT could help scientists test new drugs, vaccines for malaria

Vitamin D-deficient older individuals are more likely to struggle with everyday tasks

Exposure to PFC may increase risk of mild hypothyroidism in women

TAp73 protein frequently overexpressed in wide range of human tumors

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