Metabolism News and Research

Latest Metabolism News and Research

Metabolic cell death pathways could be novel therapeutic targets in cancer treatment

The review discusses how metabolic cell death, distinct from traditional forms of regulated cell death like apoptosis, arises from imbalances in cellular metabolism due to nutrient and metal overload or depletion.

28 May 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Study highlights a dietary strategy for health improvement and weight management

A new study by researchers from Arizona State University and their colleagues highlights a dietary strategy for significant health improvement and weight management.

28 May 2024

Underappreciated set of enzymes connected to the regulation of hippo pathway in cancer

Within the family of cell membrane lipids known as phosphoinositides and the kinase enzymes that regulate them, phosphoinositide 3-kinases (PI3Ks) have been cast in a starring role as scientists study their involvement in cancer, diabetes and many cellular activities.

28 May 2024

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

A new paper in Trends in Pharmacological Sciences from researchers at generative artificial intelligence (AI)- and robotics-powered clinical stage drug discovery company Insilico Medicine ("Insilico") and ETH Zurich reveals the broad potential of TNIK as a therapeutic target for some of the most pervasive aging-related diseases, including fibrosis, cancer, obesity, and Alzheimer's.

28 May 2024

Simple vaginal swab could help detect early-stage gynecological cancers

A simple vaginal swab could reveal the presence of early-stage gynecological cancers, according to a new, wide-ranging study published in De Gruyter's Open Life Sciences.

28 May 2024

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

A University of Saskatchewan (USask) research team's discovery of the additional health benefits of an appetite-suppressing protein has doubled the potential for scientists to find new avenues for treating obesity and metabolic disorders in animals and people.

28 May 2024

Genetic screening and counseling slash young adults' excessive drinking, new study reveals

A recent randomized controlled trial found that short-term interventions combining enzyme substances and behavioral changes significantly reduced excessive alcohol intake among young adults.

28 May 2024

Low vitamin D levels linked to higher diabetes risk in older adults, study finds

A meta-analysis found that low serum vitamin D levels significantly increase the risk of developing type 2 diabetes in older adults, even after adjusting for several confounders.

27 May 2024

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Researchers reviewed the potential therapeutic effects of phytochemicals on the gut-brain axis, finding they could influence brain function and reduce neurological symptoms by modulating gut microbiota.

26 May 2024

Targeting metabolic pathways to combat Epstein-Barr virus infections

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers.

24 May 2024

Ketogenic diet shows promise in treating anxiety, depression, and other mental health disorders, study finds

Research suggests the ketogenic diet may offer benefits in managing anxiety, depression, stress, schizophrenia, and bipolar disorder, but more clinical trials are needed to confirm its efficacy.

23 May 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Cherries and berries: Nature’s sweet remedy for a healthy heart

Research paper reviews the cardiovascular benefits of phenolic compounds in cherries and berries, highlighting their potential to reduce inflammation, oxidative stress, and improve lipid profiles. Regular consumption of these fruits can significantly lower the risk of cardiovascular diseases.

23 May 2024

Flavonoid-rich diet slashes type 2 diabetes risk by up to 28%, new study reveals

Increasing the intake of flavonoid-rich foods significantly reduces the risk of developing type 2 diabetes, according to a study in Nutrition & Diabetes.

23 May 2024

Prenatal exposure to endocrine disruptors linked to poorer metabolic health in childhood

The term 'metabolic syndrome' (MetS) encompasses a group of factors, such as abdominal obesity, hypertension and insulin resistance, that together increase the risk of cardiovascular disease and type 2 diabetes.

23 May 2024

New understanding of cancer drug's ability to prevent fat buildup in the liver

University of Oklahoma researchers have deepened their understanding of a drug's ability to prevent fat buildup in the liver, a condition that often occurs with obesity and can lead to serious fatty liver disease.

23 May 2024

Breakthrough study reveals molecular drivers of Alzheimer's progression

According to the US Centers for Disease Control and Prevention, at least 5.8 million Americans are currently living with Alzheimer's disease, which is the most common form of dementia.

23 May 2024

Researchers discover advances in predicting kidney failure in type 1 diabetes patients

In a paper published today in Science Translational Medicine, researchers from City of Hope, one of the largest cancer research and treatment organizations in the United States and a leading research center for diabetes and other life-threatening illnesses, report that they have discovered advances in predicting kidney failure in type 1 diabetes (T1D) patients.

22 May 2024

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Ferroptosis, an iron-dependent cell death mechanism, is identified as a key factor in severe COVID-19 lung disease, suggesting potential new therapeutic targets.

22 May 2024

Metabolism News and Research

Latest Metabolism News and Research

Metabolic cell death pathways could be novel therapeutic targets in cancer treatment

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

Study highlights a dietary strategy for health improvement and weight management

Underappreciated set of enzymes connected to the regulation of hippo pathway in cancer

New paper reveals the broad potential of TNIK as a therapeutic target for some aging-related diseases

Simple vaginal swab could help detect early-stage gynecological cancers

Discovery of promising protein candidate opens new avenues for treating metabolic disorders

Genetic screening and counseling slash young adults' excessive drinking, new study reveals

Low vitamin D levels linked to higher diabetes risk in older adults, study finds

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Targeting metabolic pathways to combat Epstein-Barr virus infections

Ketogenic diet shows promise in treating anxiety, depression, and other mental health disorders, study finds

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Cherries and berries: Nature’s sweet remedy for a healthy heart

Flavonoid-rich diet slashes type 2 diabetes risk by up to 28%, new study reveals

Prenatal exposure to endocrine disruptors linked to poorer metabolic health in childhood

New understanding of cancer drug's ability to prevent fat buildup in the liver

Breakthrough study reveals molecular drivers of Alzheimer's progression

Researchers discover advances in predicting kidney failure in type 1 diabetes patients

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering

Leveraging the Radian ASAP in standard casework