Metabolomics News and Research

Latest Metabolomics News and Research

Mayo Clinic receives grant from NIH to support medical research on metabolomics

Mayo Clinic is one of six new federally-funded Comprehensive Metabolomics (met-ah-bol-OH-mics) Centers to support medical research on metabolomics -- the study, at the cellular level, of how molecules are metabolized in the body.

19 Sep 2013

Scientists develop sophisticated assay to track cell growth at low nutrient concentrations

The budding yeast, Saccharomyces cerevisiae, is a prime organism for studying fundamental cellular processes, with the functions of many proteins important in the cell cycle and signaling networks found in human biology having first been discovered in yeast.

18 Sep 2013

Penn’s ITMAT symposium addresses topics of direct relevance to translational science

The Institute for Translational Medicine and Therapeutics' 7th Annual International Symposium (ITMAT) symposium, Harnessing the Paradox: Personalization and the Science of Scale, to be held in October 2013, will address topics of direct relevance to translational science.

7 Sep 2013

More than 3,000 chemicals or "metabolites" can be detected in urine, say researchers

Researchers at the University of Alberta announced today that they have determined the chemical composition of human urine. The study, which took more than seven years and involved a team of nearly 20 researchers, has revealed that more than 3,000 chemicals or "metabolites" can be detected in urine.

6 Sep 2013

Increased caffeine intake may reduce fatty liver in people with NAFLD

Surprise! Your morning cup of tea or coffee may be doing more than just perking you up before work. An international team of researchers led by Duke-NUS Graduate Medical School (Duke-NUS) and the Duke University School of Medicine suggest that increased caffeine intake may reduce fatty liver in people with non-alcoholic fatty liver disease (NAFLD).

17 Aug 2013

Metabolomics tools predict who can benefit from treatment with certain antidepressants

Duke Medicine researchers have identified biochemical changes in people taking antidepressants - but only in those whose depression improves. These changes occur in a neurotransmitter pathway that is connected to the pineal gland, the part of the endocrine system that controls the sleep cycle, suggesting an added link between sleep, depression and treatment outcomes.

19 Jul 2013

Key metabolites in blood could provide clues to long-term overall health and ageing

Scientists have found that key metabolites in blood - chemical 'fingerprints' left behind as a result of early molecular changes before birth or in infancy - could provide clues to a person's long-term overall health and rate of ageing in later life.

9 Jul 2013

Special type of IVF may increase risk for insulin resistance among children

A special type of in vitro fertilization, or IVF, may increase the risk for insulin resistance among children conceived in this way, according to a new study from Greece. The results will be presented Monday at The Endocrine Society's 95th Annual Meeting in San Francisco.

18 Jun 2013

TEDDY study enables scientists to parse genetic mutations associated with type 1 diabetes

Massive samples emanating from a decade-old, international initiative to determine how genetics and environment cause type 1 diabetes are giving scientists a unique perspective on which molecular and environmental factors really contribute to the disease.

14 Jun 2013

Sensational proteomics results enabled by Bruker’s new IMPACT HD™ Mass Spectrometer with Novel CaptiveSpray™ nanoBooster Ion Source

At the 61st ASMS conference, Bruker introduces exciting new High-Definition capabilities in proteomics and biomarker research. Patented low-noise Captivespray nanoBooster™ ionization coupled with record high-speed digitization Qq-TOF technology and steered by intelligent acquisition software defines complex samples more sharply than ever before.

10 Jun 2013

Powerful new mass spectrometry systems and solutions for life-science research, clinical research, pharma and applied markets announced by Bruker

At the 61st ASMS Conference on Mass Spectrometry and Allied Topics, Bruker today announced mass spectrometry-based product introductions for life-science and clinical research, for biotech/pharma/CRO customers, as well as for industrial and applied markets. The new mass spectrometry systems and solutions are designed to deliver confident analyses with dramatically enhanced resolution, sensitivity and precision.

10 Jun 2013

New LC-MS software to transform high performance mass spectrometry unveiled by Thermo Fisher Scientific

Thermo Fisher Scientific Inc., the world leader in serving science, today introduced 10 new or updated software packages to help customers harness the power of its new-generation liquid chromatography-mass spectrometry (LC-MS) instruments and turn data into knowledge in a wide range of discovery and quantitation experiments.

From Thermo Fisher Scientific Inc. 10 Jun 2013

World’s first “Tribrid” LC-MS launched by Thermo Fisher Scientific

Thermo Fisher Scientific Inc., the world leader in serving science, introduced the Thermo Scientific Orbitrap Fusion Tribrid liquid chromatography-mass spectrometry (LC-MS) system, combining its three mass analyzers –quadrupole, Orbitrap and linear ion trap – in a novel “Tribrid” architecture that offers unprecedented depth of analysis of complex biological samples.

From Thermo Fisher Scientific Inc. 10 Jun 2013

New Genome Canada program launched

The Honourable Gary Goodyear, Minister of State (Science and Technology), announced the launch of a new Genome Canada program designed to move genomics-based solutions from laboratories to the marketplace.

4 Jun 2013

Lupus Foundation of America announces Career Development Award and new summer fellowships

The Lupus Foundation of America, the only national force dedicated to solving the cruel mystery of lupus, announced recipients of five new summer fellowships and the Foundation's first-ever Career Development Award.

3 Jun 2013

Mayo Clinic researchers envision new way to detect early onset of Alzheimer's disease

Blood offers promise as a way to detect Alzheimer's disease at its earliest onset, Mayo Clinic researchers say. They envision a test that would detect distinct metabolic signatures in blood plasma that are synonymous with the disease -- years before patients begin showing cognitive decline.

30 May 2013

Study shows PDH enzyme plays a major role in regulation of oncogene-induced cellular senescence

An article published on the journal Nature describes the major role that Pyruvate dehydrogenase (PDH) —an enzyme of cellular energy metabolism— plays in the regulation of the cellular senescence induced by the oncogene BRAF, which usually appears mutated in melanoma and other cancers.

22 May 2013

Researchers identify novel biomarkers for predicting mortality in ICU patients

A metabolic profile of intensive care unit patients based on biomarkers of four metabolites can be used to accurately predict mortality, according to a new study.

21 May 2013

Study identifies potential drug targets that interfere with cancer metabolism

A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer.

22 Apr 2013

Matrix-Bio, Quest Diagnostics enter global licensing agreement for metabolomic biomarkers

Matrix-Bio, Inc., a diagnostics company that uses metabolite profiling to detect cancer and other diseases, has signed an exclusive global licensing and marketing agreement for metabolomic biomarkers with Quest Diagnostics, the world's leading provider of diagnostic information services. Under the agreement, Quest Diagnostics will have the rights to use the biomarkers for the future, potential development of a clinical lab-developed test to aid in the detection of breast cancer recurrence.

From Quest Diagnostics 12 Apr 2013