Metabolomics News and Research

Latest Metabolomics News and Research

Bruker introduces new products at Analytica 2012

At Analytica 2012, Bruker today announced several new product introductions for the research, industrial and applied markets, designed to deliver confident analyses with increased sensitivity, specificity and productivity, and to push the boundaries of advanced molecular and materials research applications.

18 Apr 2012

Brain mitochondria are dysfunctional in early-stage Alzheimer's

Mitochondria -- subunits inside cells that produce energy -- have long been thought to play a role in Alzheimer's disease. Now Mayo Clinic researchers using genetic mouse models have discovered that mitochondria in the brain are dysfunctional early in the disease.

1 Mar 2012

VTT participates in two new EU projects that focus on type 2 diabetes

VTT is participating in two new European projects focusing on type 2 diabetes. The projects aim at identifying new therapeutic choices and strategies for preventing the disease. Focus is on obtaining information on cellular dysfunction in diabetes and the effects of changes in lifestyle. The goal includes planning individual lifestyle instructions for people at high risk of diabetes and exploiting the results in a major European health insurance system.

22 Feb 2012

Sanford-Burnham, Florida Hospital and Moffitt partner to develop PMP Florida

Moffitt Cancer Center, Sanford-Burnham Medical Research Institute and Florida Hospital have announced they will collaborate on the creation of a Personalized Medicine Partnership of Florida (PMP Florida). The partnership will conduct collaborative research to accelerate discovery and develop new treatments in the areas of cancer and metabolic diseases, including obesity, diabetes and cardiovascular disease.

9 Feb 2012

Strong link between high HuR protein levels and malignancy of HCC

Researchers at CIC Biogune, the Cooperative Centre for Research into Biosciences and led by Dr. Maria Luz Martinez Chantar, have found a strong relationship between high levels of Hu antigen R (HuR) protein and the malignancy of Hepatocellular Carcinoma, through a novel molecular process in the investigation of this pathology and known as neddylation.

27 Jan 2012

Scientists use metabolomics to discover DMS linked with neuropathic pain

Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But a team led by scientists from The Scripps Research Institute, using a new approach known as metabolomics, has now discovered a major clue: dimethylsphingosine (DMS), a small-molecule byproduct of cellular membranes in the nervous system.

23 Jan 2012

Metabolomx' colorimetric sensor array can identify subtype of lung cancer

Metabolomx, a diagnostic company focused on the detection of the metabolomics signature of cancer from exhaled breath, today announces publication of results from the first clinical study demonstrating a breath test that can both detect lung cancer and differentiate between types of lung cancer in humans.

16 Dec 2011

Molecular signature indicative of hypoxia predicts progression to AD

A study led by Research Professor Matej Ore-ič from VTT Technical Research Centre of Finland suggests that Alzheimer's disease is preceded by a molecular signature indicative of hypoxia and up-regulated pentose phosphate pathway.

15 Dec 2011

Health benefits of nut consumption

A recent scientific study has revealed the relationship between nut consumption and a high level of serotonin metabolites (an important neurotransmitter) in patients with metabolic syndrome, who are at high risk of cardiovascular disease.

11 Nov 2011

Study provides details on genetics behind many metabolic diseases

In what is so far the largest investigation of its kind, researchers uncovered a wide range of new insights about common diseases and how they are affected by differences between two persons' genes. The results from this study could lead to highly targeted, individualized therapies.

27 Oct 2011

U-M researchers to study new approach in halting downward spiral of diabetes

University of Michigan Health System researchers will use a $3.5 million federal grant to study a new approach in halting the downward spiral of diabetes.

24 Oct 2011

Agilent announces winners of 2011 eMerging Insights grant program

Agilent Technologies Inc. today announced the winners of the 2011 eMerging Insights grant program: Dr. Michael J. MacCoss of the University of Washington and Dr. Peter J. Park of Harvard University. Each will be awarded $75,000 toward their ongoing research on open source data-integration tools.

21 Oct 2011

Gut bacteria shown to affect statin efficacy in some people

The team led by a Duke University scientist has identified three bile acids produced by gut bacteria that were evident in people who responded well to a common cholesterol-lowering drug called simvastatin. The finding, published Oct. 13, 2011, in PLoS One, demonstrates how gut bacteria can cause inherent differences in the way people digest, metabolize and benefit from substances such as drugs.

17 Oct 2011

Researchers identify gut bacteria bile acids linked to effectiveness of statin drugs in lowering cholesterol

Statins can be effective at lowering cholesterol, but they have a perplexing tendency to work for some people and not others. Gut bacteria may be the reason.

14 Oct 2011

CSIR and Mayo Clinic sign research collaboration agreement

Mayo Clinic and the top science and technology organization in India have signed an agreement to collaborate on research. Leaders from Mayo and Council of Scientific and Industrial Research (CSIR), India today signed a memorandum of understanding to work together on such topics as drug, device and biomarker studies relating to heart disease, chemical biology and applied genomics, and innovations in metabolomics.

13 Oct 2011

Scientists identify several links between genetic variants and specific metabolic changes

Scientists at Helmholtz Zentrum Munich and LMU Munich, in cooperation with Wellcome Trust Sanger Institute and King's College London (KCL), have identified several associations between genetic variants and specific metabolic changes.

3 Sep 2011

Nature journal publishes Metabolon's genome wide association study

Metabolon, Inc., the leader in metabolomics, biomarker discovery and biochemical analysis, announced the publication of "Human Metabolic Individuality in Biomedical and Pharmaceutical Research" in the journal Nature.

3 Sep 2011

New guidelines for the treatment of acromegaly, a serious growth hormone disorder

It’s said a lot can happen in seven days. In seven years, a lot has happened in the understanding of acromegaly, a debilitating condition that causes a patient to have too much growth hormone. It’s seven years since the American Association of Clinical Endocrinologists last produced guidelines for the diagnosis and treatment of acromegaly. Their 2004 guidelines were just 13 pages long. Their latest, the 2011 guidelines, have grown – to 44 pages.

31 Aug 2011

Insight into acrolein-induced acute lung injury

Metabolon, Inc., the leader in metabolomics, biomarker discovery and biochemical analysis, announces the publication of "Integrative Metabolome and Transcriptome Profiling Reveals Discordant Energetic Stress Between Mouse Strains with Differential Sensitivity to Acrolein-Induced Acute Lung Injury" in The Molecular Nutrition and Food Research Journal.

24 Aug 2011

Metabolic profile reveals need for gender-specific therapies

Analyses of the metabolic profile of blood serum reveal significant differences between men and women. From their tests, scientists at the Helmholtz Zentrum München have concluded that there is a need for gender-specific therapies. The study was financed by the German Centre for Diabetes Research and was published in the current edition of the internationally renowned peer-reviewjournal PLoS Genetics.

12 Aug 2011