Microbiome News and Research

Latest Microbiome News and Research

Bacteria require phase separation to thrive in the mammalian gut

The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study in mice.

17 Mar 2023

Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

Diagnosis and treatment of food allergies using a molecular approach

Researchers discuss molecular methods for food allergy assessments, including diagnostic and prognostic markers, as well as existing therapies.

15 Mar 2023

The role of the fungal mycobiome in women's health

Researchers discuss the association between human mycobiota and female health.

15 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Using probiotics to treat depression

Researchers discuss whether probiotics could be used as supplementary or primary therapy to manage major depressive disorder.

15 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

15 Mar 2023

Mediterranean diet associated with reduction in woman's risks of cardiovascular disease and death

Sticking closely to a Mediterranean diet may cut a woman's risks of cardiovascular disease and death by nearly 25%, finds a pooled data analysis of the available evidence—the first of its kind—published online in the journal Heart.

15 Mar 2023

Age and sex determine the effects of microbiota on mice's metabolome

The gut handles all ingested foods for further digestion and assimilation. In addition, it harbors a wealth of microbes that produce metabolic byproducts with multiple effects on host physiology. Therefore, changes in the gut microbiome's composition can shift the gut's metabolome as well.

15 Mar 2023

How does the gut microbiome affect muscle strength?

Researchers use fecal microbiome transplantation in mouse models to examine the role of gut microbiota in determining muscle strength.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

A growing body of evidence is showing that the healthy gut microbiome – a community of microorganisms that live together in the gut – influences many aspects of human growth and development, especially during adolescence.

14 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

The development of the pediatric oral resistome and its role in dental caries

Researchers performed a genomic investigation of oral resistome development, i.e., of genes that confer antimicrobial resistance.

14 Mar 2023

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP).

14 Mar 2023

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

In a recent review published in the European Journal of Endocrinology, researchers discussed current research on the relationship between human obesity and inflammation of the hypothalamus.

14 Mar 2023

The burden of Clostridioides difficile infections in the United States

Researchers review existing data on Clostridioides difficile infections among United States residents.

13 Mar 2023

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Not all probiotics are created equal. In a new study, researchers found that certain enzymes within a class known as bile salt hydrolases (BSHs) can restrict Clostridioides difficile (C. diff.) colonization by both altering existing bile acids and by creating a new class of bile acids within the gut's microbial environment.

13 Mar 2023

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Even though, according to recent preliminary studies, the risk of dying from cancer has declined within the European Union in recent years, cancers remain among the leading causes of death.

13 Mar 2023

Microbiome News and Research

Latest Microbiome News and Research

Bacteria require phase separation to thrive in the mammalian gut

Study implicates gut microbiome and immune response in hospital-acquired infections

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Diagnosis and treatment of food allergies using a molecular approach

The role of the fungal mycobiome in women's health

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Using probiotics to treat depression

High consumption of common artificial sweetener lowers activation of T-cells in mice

Mediterranean diet associated with reduction in woman's risks of cardiovascular disease and death

Age and sex determine the effects of microbiota on mice's metabolome

How does the gut microbiome affect muscle strength?

Study identifies link between oral and gut microbiomes and depression

Long-term antibiotic therapy for adolescent acne can affect liver metabolism and promote adiposity

Host immune system forms small lesions in the intestines in response to bacterial infection

The development of the pediatric oral resistome and its role in dental caries

Distinct microbial profile present in intrahepatic cholestasis of pregnancy patients

Hypothalamic inflammation and obesity, study suggests a pathological mechanism

The burden of Clostridioides difficile infections in the United States

The right combination of bile salt hydrolases may offer a new approach to treat C. diff

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Microbiology eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

Microbiome News and Research

Latest Microbiome News and Research

Microbiology eBook

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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