Microbiome

The varied community of microorganisms that live in different parts of the body, particularly the gut, is referred to as the human microbiome. These microorganisms are mostly bacteria, but they can also be viruses, fungi, and archaea. These microbial communities are vital for immune regulation, nutrition synthesis, digestion, and pathogen defense. Metagenomics research has shown that homeostasis depends on a healthy, diverse microbiome, whereas dysbiosis, or imbalances in the microbiome, is linked to a variety of illnesses, such as obesity, inflammatory bowel disease, allergies, and neuropsychiatric disorders. The field of microbiome research is growing quickly, providing new information on diet-microbe interactions, probiotic treatments, and personalized medicine.

Ovarian Microbiome Overview: Fertility, PCOS, and the Gut–Ovary Axis

New insights into the ovarian microbiome reveal both promise and controversy, challenging long-held assumptions about reproductive health and opening doors to targeted therapies for infertility and PCOS.

Fermented Foods and Gut Health

Effects of a Gluten-Free Diet on the Gut Microbiota

Alzheimer's Disease and the Microbiome

Risk Factors for Small Intestinal Bacterial Overgrowth

Gut Bacteria and Autism Development

Parkinson's Disease and the Gut Microbiome

Is There a Link Between Migraine and the Gut Microbiome?

Vaginal Microbiome and Premature Birth

What Role do Microbiomes Play in Urinary Tract Infections?

Can you Treat a Food Allergy by Altering the Gut Microbiome?

What is Vaginal Microbiome?

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Semi-Volatile Organic Compounds (SVOCs) and the Microbiome

The Effect of Intermittent Fasting on the Gut Microbiome

Human Microbiome Project (HMP)

What is the Human Virome?

How Artificial Sweeteners Disrupt the Gut Microbiome, Or Do They?

Oral Microbiota

Scalp Microbiome Explained: What’s Living on Your Scalp and Why It Matters

How “Fad” Diets Affect the Gut Microbiota

Fecal Microbiota Transplant

Fecal Microbiota Transplant Technique

Menopause and the Microbiome

How Does the Diet Impact Microbiota?

How Does Your Diet Affect your Gut Microbiome?

The Microbiome of a Newborn

Insight into the Skin Microbiome

The Microbiome and Aging

Human Microbiome

Fecal Microbiota Transplant Regulation

What Role Does the Immune System and Microbiome Play in Health and Disease?

Gut Microbiota

Does the Microbiome Interact with the Human Endocrine System?

Skin Microbiota

Microbiome and Cancer

Is Coffee Good for the Gut?

Microbiome and Disease

Genetic Factors that Influence Bacterial Diversity in the Human Gut

Disease Susceptibility and the Microbiome

Do Serotonin and Antidepressants Affect the Microbiome?

Conjunctiva microbiota

Drug Metabolism and Microbiome

Microbiome-Host Cell Interactions

Achievements of the Human Microbiome Project

Is There a Brain Microbiome?

Antibiotics and the Microbiome

Latest Microbiome News and Research

Social living allows genetic effects to spread through the gut microbiome

Your "roommate's" genes could be influencing the bacteria living in your gut, and vice versa, according to a study of rats published today in Nature Communications.

18 Dec 2025

Research reveals how the gut microbiome supports successful pregnancy

Gut microbes may play a key role in training a mother's immune system to adapt to the developing fetus during pregnancy, according to a preclinical study by Weill Cornell Medicine investigators.

17 Dec 2025

Early life gut microbiome crucial for immune system development

Antibiotics are powerful treatments that have saved countless lives over the course of decades. New findings from Scripps Research have identified a way to preserve healthy immune development even when infants need antibiotic treatment.

17 Dec 2025

How Traditional Chinese Medicine may reshape the gut microbiome to ease insulin resistance in PCOS

This review synthesizes evidence that gut microbiota dysbiosis contributes to insulin resistance and symptom severity in polycystic ovary syndrome through impaired barrier function, inflammation, and altered microbial metabolites. It evaluates how Traditional Chinese Medicine may modulate these pathways while highlighting major gaps in clinical validation, safety, and standardization.

16 Dec 2025

Specific gut bacterium reduces weight gain and improves metabolic health

The gut microbiome is intimately linked to human health and weight. Differences in the gut microbiome-the bacteria and fungi in the gut-are associated with obesity and weight gain, raising the possibility that changing the microbiome could improve health.

16 Dec 2025

Frog-derived bacteria offer dual-action anticancer effects and high safety

A research team of Prof. Eijiro Miyako at the Japan Advanced Institute of Science and Technology (JAIST) has discovered that the bacterium Ewingella americana, isolated from the intestines of Japanese tree frogs (Dryophytes japonicus), possesses remarkably potent anticancer activity. This groundbreaking research has been published in the international journal Gut Microbes.

16 Dec 2025

Scientists map how cinnamon’s bioactives interact with cancer signaling

This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.

15 Dec 2025

Gut bacteria patterns differ in autism and siblings and link to social symptoms

This sibling-controlled East Asian study found that autistic individuals, their unaffected siblings, and typically developing controls differ in gut microbiota diversity and composition, with the clearest separation between autism and typical development. Specific taxa, particularly the butyrate-producing genus Anaerostipes, were modestly associated with social communication and internalising symptoms, supporting a gut–behaviour link without implying causality.

15 Dec 2025

Advances in delivering oxygen-sensitive gut bacteria improve microbial therapies

Recent research has identified practical ways to protect and deliver oxygen-sensitive gut bacteria for a path toward safer, standardized microbial therapies that could reduce reliance on donor-based faecal microbiota transplants.

15 Dec 2025

What drinking kefir really does to your gut and oral microbiome

The impact of kefir on gut and oral microbiomes shows promise, but inconsistent findings and study limitations call for more rigorous scientific investigation.

15 Dec 2025

Understanding how the immune system protects against fungal pathogenicity

The yeast Candida albicans colonizes mucosal surfaces and is usually harmless. However, under certain conditions it can cause dangerous infections.

15 Dec 2025

Gut bacteria mimicry can accelerate the progression of multiple sclerosis

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system.

15 Dec 2025

A new trial investigates whether the MIND diet can be scaled for obesity management

This study protocol outlines a 12-week randomized trial testing whether a MIND diet intervention is feasible, acceptable, and sustainable for adults with obesity in Sweden. It will generate preliminary evidence on adherence, mental well-being, and gut microbiota changes to inform larger efficacy trials.

14 Dec 2025

Researchers develop powerful tools for microbiome research advancement

The microscopic organisms that fill our bodies, soils, oceans and atmosphere play essential roles in human health and the planet's ecosystems. Yet even with modern DNA sequencing, figuring out what these microbes are and how they are related to one another remains extremely difficult.

13 Dec 2025

How ultra-processed foods shape Crohn’s disease risk and what dietary strategies can really help

This narrative review synthesizes evidence showing that higher intake of ultra-processed foods is consistently associated with increased Crohn’s disease risk, with mechanistic pathways implicating emulsifiers, carrageenan, maltodextrin, titanium dioxide, sweeteners and salt. It also highlights that minimally processed dietary strategies, including EEN and CDED, show therapeutic promise, particularly in pediatric Crohn’s disease.

11 Dec 2025

Discovery links human M cells to early steps of celiac disease

The human small intestine absorbs nutrients while protecting us from potentially harmful microbes. One of the cell types that plays a key role in this protection is the microfold cell, or M cell.

10 Dec 2025

Filtered coffee shows a causal link to healthier HbA1c levels

Genetically predicted filtered coffee consumption is causally associated with lower HbA1c levels, while other coffee preparation methods show no such benefit. This effect appears to be partly mediated by increases in propionate producing gut bacteria, particularly Veillonella.

10 Dec 2025