Microbiome

The varied community of microorganisms that live in different parts of the body, particularly the gut, is referred to as the human microbiome. These microorganisms are mostly bacteria, but they can also be viruses, fungi, and archaea. These microbial communities are vital for immune regulation, nutrition synthesis, digestion, and pathogen defense. Metagenomics research has shown that homeostasis depends on a healthy, diverse microbiome, whereas dysbiosis, or imbalances in the microbiome, is linked to a variety of illnesses, such as obesity, inflammatory bowel disease, allergies, and neuropsychiatric disorders. The field of microbiome research is growing quickly, providing new information on diet-microbe interactions, probiotic treatments, and personalized medicine.

The Gut–Brain–Skin Axis: How Diet and Gut Health Influence Mood, Skin, and Aging

How microbial metabolites from everyday foods connect the gut, brain, and skin to influence inflammation, emotional health, and the biology of aging.

Ovarian Microbiome Overview: Fertility, PCOS, and the Gut–Ovary Axis

Effects of a Gluten-Free Diet on the Gut Microbiota

Parkinson's Disease and the Gut Microbiome

How Does Your Diet Affect your Gut Microbiome?

The Microbiome and Aging

The Effect of Intermittent Fasting on the Gut Microbiome

Scalp Microbiome Explained: What’s Living on Your Scalp and Why It Matters

Conjunctiva microbiota

Does the Microbiome Interact with the Human Endocrine System?

Can you Treat a Food Allergy by Altering the Gut Microbiome?

Is There a Link Between Migraine and the Gut Microbiome?

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Human Microbiome Project (HMP)

How Does the Diet Impact Microbiota?

Fermented Foods and Gut Health

Is Coffee Good for the Gut?

Drug Metabolism and Microbiome

Disease Susceptibility and the Microbiome

Fecal Microbiota Transplant

Microbiome-Host Cell Interactions

Achievements of the Human Microbiome Project

Do Serotonin and Antidepressants Affect the Microbiome?

Fecal Microbiota Transplant Regulation

Is There a Brain Microbiome?

How “Fad” Diets Affect the Gut Microbiota

Insight into the Skin Microbiome

Vaginal Microbiome and Premature Birth

Fecal Microbiota Transplant Technique

What is the Human Virome?

Microbiome and Disease

The Microbiome of a Newborn

Human Microbiome

Oral Microbiota

What Role do Microbiomes Play in Urinary Tract Infections?

Semi-Volatile Organic Compounds (SVOCs) and the Microbiome

Menopause and the Microbiome

What is Vaginal Microbiome?

Gut Bacteria and Autism Development

Antibiotics and the Microbiome

Risk Factors for Small Intestinal Bacterial Overgrowth

Alzheimer's Disease and the Microbiome

Gut Microbiota

Skin Microbiota

How Artificial Sweeteners Disrupt the Gut Microbiome, Or Do They?

Microbiome and Cancer

Genetic Factors that Influence Bacterial Diversity in the Human Gut

What Role Does the Immune System and Microbiome Play in Health and Disease?

Latest Microbiome News and Research

New microbiome therapy improves autism symptoms in children

This study evaluates a new fecal microbiota transplant method, revealing significant symptom improvements in children with autism without invasive procedures.

18 Mar 2026

Implantable device boosts immune cells to fight cancer effectively

Immunotherapy has transformed cancer treatment by harnessing the body's own immune system to fight disease.

17 Mar 2026

How one antibiotic dose can reshape your gut microbiome for years

Long-term registry-linked analysis of nearly 15,000 adults shows that antibiotic use is associated with persistent changes in gut microbiome diversity and composition for up to 4–8 years. These effects vary by antibiotic class, with clindamycin, fluoroquinolones, and flucloxacillin showing the strongest and most sustained associations.

17 Mar 2026

New CAR-NKT cell therapy shows promise against aggressive endometrial cancer

Endometrial cancer is the most common gynecologic cancer in the United States and is one of the few cancers in which survival rates have steadily declined over the last few decades.

16 Mar 2026

Why do some people respond better to GLP-1 drugs? Gut microbiome may hold clues

A review in the Canadian Journal of Physiology and Pharmacology examines emerging evidence linking glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the gut microbiome, and obesity treatment outcomes. The authors conclude that microbiome changes seen during therapy are most likely driven by diet, behavior, and weight loss, although microbial profiling may eventually help predict patient responses.

15 Mar 2026

Vaginal microbiome may play key role in pregnancy health and preterm birth risk, researchers say

Researchers reviewed evidence linking the vaginal microbiome to pregnancy health and spontaneous preterm birth, highlighting how Lactobacillus-dominated communities help maintain immune balance and vaginal acidity. Dysbiosis and inflammatory signaling may contribute to preterm birth risk, while emerging microbiome-targeted therapies aim to restore protective microbial ecosystems.

15 Mar 2026

Scientists show gut bacteria can reach the brain in mice and reveal a potential vagus nerve pathway

Researchers found that very small numbers of gut bacteria can translocate to the brain in mice, particularly when gut barrier permeability increases due to a Paigen diet. Evidence suggests the vagus nerve may serve as a partial route for this gut-to-brain microbial movement.

15 Mar 2026

Gut microbes may drive memory decline during aging by disrupting vagal brain signaling

Researchers identified in mice a microbiome–gut–brain pathway in which age-associated changes in gut microbes increase medium-chain fatty acids that impair vagal sensory signaling and hippocampal activity. These interoceptive disruptions weaken memory formation, revealing a microbial mechanism that contributes to cognitive decline during aging.

12 Mar 2026

High fat diets allow gut bacteria to enter the brain via the vagus nerve

With more than 100 million neurons in the digestive tract, the gut is commonly known as the "second brain" in numerous cultures, including ancient Greece, Japan, China and India, linking digestion with physical and mental well-being.

12 Mar 2026

Prebiotic fiber supplement lowers pain sensitivity in people with knee osteoarthritis

A new study has found that a prebiotic fiber supplement reduced pain, improved grip strength, and lowered pain sensitivity in people with knee osteoarthritis (OA) - with far fewer dropouts than a digital physiotherapy programme.

12 Mar 2026

Scientists uncover how the immune system actively builds food tolerance

Food allergies are serious and, for some, potentially deadly. And yet, despite decades of research into allergies and what causes them, very little is known about why the vast majority of people are able to tolerate foods that can sicken or even kill others.

11 Mar 2026

How the aging gastrointestinal tract drives age-related cognitive decline

We become forgetful as we age. This is often seen as a universal truth, but in fact it is far from universal: some people remain incredibly sharp at 100 years old, while others experience memory loss starting in middle age.

11 Mar 2026

Severe COVID and flu infections increase risk of lung cancer

Severe COVID-19 and influenza infections prime the lungs for cancer and can accelerate the disease's development, but vaccination heads off those harmful effects, new research from UVA Health's Beirne B. Carter Center for Immunology Research and UVA Comprehensive Cancer Center indicates.

11 Mar 2026

Some antibiotics alter gut microbiome composition for up to eight years

Antibiotic treatments can affect the composition of the community of bacteria living in the gut, known as the gut microbiome, for a long time.

11 Mar 2026

Specific gut microbe may boost muscle strength and performance

A species of gut bacteria called Roseburia inulinivorans is specifically associated with human muscle strength and improved muscular performance in mice, finds research published online in the journal Gut.

10 Mar 2026

Gut microbiome-produced nicotinic acid protects colon tissue from injury

The gut microbiome-the trillions of bacteria and other microbes that inhabit the gastrointestinal tract-drives a process vital for protecting the colon against tissue injury, according to the findings of a study co-led by Cedars-Sinai Health Sciences University investigators.

10 Mar 2026

How social and environmental exposures across life influence mental health risk

Researchers outline how the exposome framework, which captures the totality of environmental exposures across the lifespan, can help explain how non-genetic factors shape mental health risk and resilience. The perspective highlights how integrating environmental, biological, and social data could improve prevention strategies, research models, and personalized mental health care.

10 Mar 2026

Postbiotics may help treat PCOS by restoring microbiome balance

Emerging studies suggest postbiotics could aid PCOS management by restoring gut microbiome balance and enhancing insulin sensitivity and hormonal regulation.

10 Mar 2026

Hormonal imbalance and gut microbes linked to cognitive deficits in patients with PitNETs

Pituitary neuroendocrine tumors (PitNETs) are commonly associated with visual disturbances and endocrine abnormalities; however, many patients also experience cognitive deficits, particularly in memory, attention, and executive function, which significantly affect quality of life.

9 Mar 2026

Specific gut bacteria may signal long-term risk of heart and metabolic disease

Researchers analyzed gut microbiome profiles from 4,792 adults in the HELIUS cohort and tracked cardiometabolic outcomes over time to determine whether specific microbes predict disease risk. Certain microbes were linked to higher or lower cardiovascular risk, while plant-derived microbial metabolites suggested potential diet–microbiome interactions influencing heart health.

9 Mar 2026