Nervous System News and Research

Latest Nervous System News and Research

AI trained on 9 trillion DNA letters predicts harmful mutations and designs new genomes

Scientists developed Evo 2, a large biological foundation model trained on about 9 trillion DNA base pairs that can analyse genomic sequences across bacteria, plants, and humans. The model predicts functional effects of genetic variants and can generate genome-scale DNA sequences, enabling new approaches to studying and designing biological systems.

5 Mar 2026

Researchers propose that Parkinson’s disease may start in the gut, not the brain

A perspective in The Journal of Clinical Investigation argues that environmental exposures may interact with the gut microbiome and intestinal barrier to trigger biological processes linked to Parkinson’s disease. The authors propose that cumulative environmental stressors can erode host resilience, promoting α-synuclein pathology, immune activation, and neurodegeneration.

5 Mar 2026

High use of anticholinergic drugs linked to increased cardiovascular disease risk

People who use drugs with anticholinergic effects, including certain antidepressants, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease.

5 Mar 2026

Youth football accounts for nearly one in five sports-related brain injuries

Youth football accounts for the largest share of sports‑related traumatic brain injuries (TBIs) in children and young adults, nearly one in every five TBIs, according to a preliminary study released March 4, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

5 Mar 2026

Wearable sensors as a tool for MS monitoring

Wearable sensors may help identify people with multiple sclerosis (MS) who are more likely to have worsening disability and loss of brain volume, according to a study published on March 4th, 2026, in Neurology®, the medical journal of the American Academy of Neurology.

4 Mar 2026

Canadian wildfire pollution associated with increased stroke severity

Short-term surges in air pollution in New Jersey from the 2023 Canadian wildfires were associated with a higher stroke rate and more serious strokes, according to a preliminary study released March 3, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

3 Mar 2026

New blood biomarker may detect Alzheimer’s pathology more accurately

Researchers compared total plasma pTau217 with a brain-derived pTau217 assay to determine which better identifies Alzheimer’s disease–related amyloid and tau pathology. Brain-derived pTau217 showed strong diagnostic performance and appeared less affected by kidney dysfunction, supporting its potential as a more specific blood biomarker for Alzheimer’s disease.

3 Mar 2026

Brain reward responses shift based on expectations about sweeteners

Elena Mainetto, from Radboud University, Margaret Westwater, from the University of Oxford, and colleagues at the University of Cambridge explored whether they could change how much people enjoy beverages containing sugar or artificial sweeteners by manipulating previous expectations about the drinks.

2 Mar 2026

Brain region linked to preference for alcohol over social rewards

People with alcohol use disorders tend to prioritize alcohol over alternative rewards, and the neural underpinnings of this are unclear.

2 Mar 2026

Study finds association between groundwater age and Parkinson’s risk

People whose drinking water came from newer groundwater had a higher risk of developing Parkinson's disease than those whose drinking water came from older groundwater, according to a preliminary study released March 2, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

2 Mar 2026

The surprising neurological benefits of GLP-1s

For people with chronic migraine, taking glucagon-like peptide-1 receptor agonists, or GLP-1 drugs, for other conditions such as diabetes and weight loss, was associated with fewer emergency department visits and hospitalizations overall, and with less need for medications used to stop and prevent migraine attacks, according to a preliminary study released March 1, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

2 Mar 2026

Investigating microglia’s role in Alzheimer’s pathology

Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. Microglia, as central nervous system (CNS) resident macrophages, are key to AD pathology. Indeed, microglia aggregation around amyloid-β (Aβ) deposits is an AD hallmark.

1 Mar 2026

Acoziborole receives positive opinion for single-dose sleeping sickness treatment

The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has granted a positive opinion to Acoziborole Winthrop (acoziborole) as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults as well as in adolescents 12 years and older weighing at least 40 kilograms.

27 Feb 2026

To avoid care disruptions, know when the clock runs out on your prior authorization

A woman with multiple sclerosis wanted to be able to walk up the stairs at home without losing her balance.

27 Feb 2026

Pomegranate’s hidden fiber-bound polyphenols significantly increase total antioxidant capacity

Researchers showed that pomegranate fruit extract contains substantial levels of non-extractable polyphenols bound within its fibre-rich matrix, significantly increasing its total measured antioxidant capacity. In human neuronal and astrocytic cell lines, the extract reduced hydrogen peroxide–induced oxidative stress, particularly in astrocytes, under in vitro conditions.

26 Feb 2026

Rising vitamin K shot refusal increases newborn brain injury risk

Increasing numbers of parents are refusing vitamin K shots for their newborns, putting infants at greater risk of avoidable brain injuries, according to a preliminary systematic review released February 26, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

26 Feb 2026

Study finds sharp drop in benzodiazepine use among older adults

Benzodiazepine treatment declined among U.S. adults between 2018 and 2022, with the steepest drop among adults ages 56 and older, according to a new study by researchers at the Columbia University Mailman School of Public Health and Columbia University Irving Medical Center.

25 Feb 2026

Morning chronotype and exercise associated with reduced ALS risk

Being an early bird, also called a morning person, and being more physically active are associated with lower risks of amyotrophic lateral sclerosis (ALS), according to a preliminary study released February 25, 2026, that will be presented at the American Academy of Neurology's 78th Annual Meeting taking place April 18-22, 2026, in Chicago and online.

25 Feb 2026

Smoking status influences Parkinson's disease risk and mortality outcomes

A new study of smokers finds that currently smoking is associated with a lower risk of developing Parkinson's disease, but quitting smoking was associated with a lower risk of death.

25 Feb 2026

Study finds brain changes related to worse memory in football players with repetitive head impacts

In former college and professional football players, a new study has found higher levels of inflammation were associated with worse brain structure, which in turn was related to worse memory.

25 Feb 2026