Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Researchers use innovative method to screen kinases for cancer drug's effectiveness

In recent years, a powerful suite of drugs known as kinase inhibitors have been developed to treat cancer and other diseases. Primary targets of such drugs include a family of receptor tyrosine kinases (RTKs) which protrude from cell surfaces like antennae and can activate cancer-related pathways in virtually all types of cancer when signaling molecules bind with them.

5 Feb 2018

Researchers reveal important role of estrogen in neuroblastoma

The female sex hormone estrogen can perform an important role in neuroblastoma, a form of cancer mainly affecting young children.

29 Jan 2018

$Study uncovers genomic targets in refractory neuroblastoma$

Study uncovers genomic targets in refractory neuroblastoma

Neuroblastoma (NB) is the most common solid tumor found in children. It starts in some very early forms of nerve cells found in the embryo or fetus.

28 Dec 2017

Scientists provide detailed insight into molecular mechanisms of ALS

Scientists have revealed more details of the molecular mechanism behind neuronal cell death in amyotrophic lateral sclerosis (ALS), a step forward to find ways to control progression of the disease.

26 Dec 2017

FDA-approved drug to treat high blood pressure increases life span in worms

UT Southwestern Medical Center researchers find that an FDA-approved drug to treat high blood pressure seems to extend lifespan in worms via a cell signaling pathway that may mimic caloric restriction.

21 Dec 2017

CHLA receives more than $1 million from St. Baldrick's Foundation for cancer research

Three physician-researchers with the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles have been awarded more than $1 million in grants from the St. Baldrick's Foundation, the largest private funder of childhood cancer research.

14 Nov 2017

Proton beam therapy has lower rates of toxicity in pediatric patients with head and neck cancer

Pediatric patients with head and neck cancer can be treated with proton beam therapy (PBT) instead of traditional photon radiation, and it will result in similar outcomes with less impact on quality of life.

23 Oct 2017

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Pediatric researchers investigating the childhood cancer neuroblastoma have identified common gene variants that raise the risk of an aggressive form of that disease. The discovery may assist doctors in better diagnosing subtypes of neuroblastoma.

25 Sep 2017

Researchers identify molecular pathway that causes immune cells to promote cancer

Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles have identified new findings about an immune cell - called a tumor-associated macrophage - that promotes cancer instead of fighting it.

21 Sep 2017

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Oncology researchers studying high-risk children's cancers have identified a protein that offers a likely target for immunotherapy--harnessing the immune system in medical treatments. In cell cultures and animal models, a potent drug attached to an antibody selectively zeroes in on cancer cells without harming healthy cells.

11 Sep 2017

Scientist receives NIH grant to investigate tumor microenvironment from relatively new context

Cancer metastasis – the spread of disease from the original site to a distant organ – remains a major challenge in treating cancer and a main cause of morbidity and mortality.

6 Sep 2017

Mayo Clinic research clarifies relationship between two genes that fuel neuroblastoma spread

For the first time, Mayo Clinic researchers and colleagues present data on how nervous system tumors, called neuroblastomas, spread. Their paper, published in Cancer Cell, clarifies the relationship between two genes that fuel the aggressive spread of neuroblastomas.

1 Sep 2017

St. Jude creates world’s largest collection of pediatric solid tumor samples

In an effort to improve outcomes for patients with some of the deadliest childhood cancers, St. Jude Children's Research Hospital scientists have created the world's largest collection of pediatric solid tumor samples, drug-sensitivity data and related information and have made the resource available at no charge to the global scientific community.

31 Aug 2017

Complex sugar molecules could help in early detection of tumors

Scientists from the University of Würzburg have synthesized a complex sugar molecule which specifically binds to the tumor protein Galectin-1. This could help to recognize tumors at an early stage and to combat them in a targeted manner.

14 Aug 2017

New biomarker assay improves detection, assessment of neuroblastoma

Investigators at The Saban Research Institute of Children's Hospital Los Angeles have developed and tested a new biomarker assay for quantifying disease and detecting the presence of neuroblastoma even when standard evaluations yield negative results for the disease.

23 Jun 2017

Could a blood test predict how cancer spreads in children?

Traditionally, we use biopsies to try to predict how cancer spreads. There are a number of molecular markers that are used, but biopsy is a limited approach. Now, the current trend is to use liquid biopsy, which is basically a blood sample.

21 Jun 2017

Research findings lay groundwork for developing more targeted treatments for deadly neuroblastomas

Genetic variations appear to pre-dispose children to developing certain severe forms of neuroblastoma, according to new research by the University of Chicago Medicine. The findings lay the groundwork for developing more targeted treatments for particularly deadly variations of the cancer.

20 Jun 2017

Findings may contribute to better understanding of aging and cancer development

A team of researchers led by Dr. Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging.

14 Jun 2017

Study finds steady decline in severe health problems for childhood cancer survivors

Treatments for childhood cancer are often intense and carry the risk of lifelong health problems for survivors. An analysis of 23,600 childhood cancer survivors in the Childhood Cancer Survivor Study (CCSS), funded by the National Institutes of Health, found that the rate of severe health problems occurring five or more years after diagnosis has declined over time.

5 Jun 2017

Researchers identify genetic mutations that predict better prognosis for neuroblastoma patients

The annual mortality rate in childhood cancer of the sympathetic nervous system, or neuroblastoma, is 10 per million between the ages of 0 and 4. The collaborative work between Basque and Valencian researchers has served to identify some genetic mutations that will help to improve the treatment of this disease.

19 May 2017

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Researchers use innovative method to screen kinases for cancer drug's effectiveness

Researchers reveal important role of estrogen in neuroblastoma

Study uncovers genomic targets in refractory neuroblastoma

Scientists provide detailed insight into molecular mechanisms of ALS

FDA-approved drug to treat high blood pressure increases life span in worms

CHLA receives more than $1 million from St. Baldrick's Foundation for cancer research

Proton beam therapy has lower rates of toxicity in pediatric patients with head and neck cancer

Pediatric researchers discover gene variants related to aggressive form of neuroblastoma

Researchers identify molecular pathway that causes immune cells to promote cancer

Researchers identify protein that offers likely target for treating high-risk pediatric cancers

Scientist receives NIH grant to investigate tumor microenvironment from relatively new context

Mayo Clinic research clarifies relationship between two genes that fuel neuroblastoma spread

St. Jude creates world’s largest collection of pediatric solid tumor samples

Complex sugar molecules could help in early detection of tumors

New biomarker assay improves detection, assessment of neuroblastoma

Could a blood test predict how cancer spreads in children?

Research findings lay groundwork for developing more targeted treatments for deadly neuroblastomas

Findings may contribute to better understanding of aging and cancer development

Study finds steady decline in severe health problems for childhood cancer survivors

Researchers identify genetic mutations that predict better prognosis for neuroblastoma patients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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