Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Researchers develop synthetic molecules that deliver drugs to neuroblastoma

Researchers from Universidad Politécnica de Madrid are involved in the development of specific molecular scaffolds which are able to deliver drugs and diagnostic agents to the neuroblastoma, an aggressive tumor in children.

27 May 2019

Potential new therapeutic approach identified for neuroblastoma tumors

Research led by Michael Lan, PhD, Professor of Pediatrics and Genetics at LSU Health New Orleans School of Medicine, found that a compound named 5'-iodotubercidin (5'-IT) suppresses the growth of neuroblastoma cells and identified a potential new therapeutic approach for the disease.

12 Apr 2019

Study describes vulnerability shared by large subset of cancer cell lines

Cancer cells adapt to potentially fatal mutations and other molecular malfunctions by adjusting one or more other genes' activity, in the process becoming dependent on those genes for their survival and growth.

12 Apr 2019

Proton therapy shows excellent outcomes, minimal side effects in high-risk neuroblastoma patients

Researchers from Children's Hospital of Philadelphia and the Perelman School of Medicine at the University of Pennsylvania analyzed the largest cohort to date of pediatric patients with high-risk neuroblastoma treated with proton radiation therapy, finding both that proton therapy was effective at reducing tumors and demonstrated minimal toxicity to surrounding organs.

10 Apr 2019

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells.

14 Mar 2019

Causes of disease including infant cancer can be revealed with new tool from Princeton University research team

Machine learning is being used to gain insight into the causes of hundreds of diseases, with Princeton University researchers discovering four specific genes that contribute to infant cancer.

4 Mar 2019

New tool uncovers molecular causes of different diseases

Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously.

1 Mar 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

New research uncovers crucial link between polyamines and MYCN

The MYCN oncogene has long been known to be a key cause of a number of deadly solid tumor cancers, including neuroblastoma, which claims more lives of children under the age of 5 than any other cancer.

4 Feb 2019

Researchers gain new insights into pediatric tumors

Peripheral nervous system tumors are one of the most common types of childhood tumors. While some of these tumors, known as neuroblastoma, disappear on their own without treatment, others will continue to grow even despite intensive treatment.

10 Dec 2018

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

The National Cancer Institute has awarded David Cheresh, PhD, Distinguished Professor and vice chair of Pathology at University of California San Diego School of Medicine, with a $4.2 million Outstanding Investigator Award to continue his research into cancer's ability to overcome stress, gain drug resistance and metastasize.

10 Dec 2018

UCR postdoctoral researcher wins prestigious NIH fellowship to study neural crest cells

Rebekah Charney, a postdoctoral researcher in the School of Medicine at the University of California, Riverside, has been awarded the prestigious Ruth L. Kirschstein National Research Service Award Individual Postdoctoral Fellowship by the National Institute of Dental and Craniofacial Research of the National Institutes of Health.

6 Dec 2018

Researchers reveal how some cancers trick healthy cells into protecting tumors

Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so aggressive that outcome is poor, even after early diagnosis and chemotherapy.

30 Nov 2018

Scientists harness power of natural killer cells to treat children with neuroblastoma

Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer (NK) cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies.

14 Nov 2018

New hope for children with aggressive form of cancer

Children with an aggressive form of cancer are being given new hope in a world-first trans-Atlantic clinical trial that will test a new three-part treatment.

10 Oct 2018

Scientists identify new biomarker for Alzheimer's disease of sporadic origin

The objective of the research, undertaken in the laboratories of the IBPM, is to develop a model for studying Alzheimer's disease of sporadic origin, in other words, not due to a hereditary genetic mutation.

10 Oct 2018

Study using DFMO shows positive results for children with high risk neuroblastoma

A paper published September 27 in Scientific Reports shows the positive results of a phase II clinical trial using the oral medication DFMO to prevent relapse in children with High Risk Neuroblastoma.

1 Oct 2018

Researchers identify new genetic disorder in a human patient

Researchers from Michigan State University College of Human Medicine and physicians from Spectrum Health have identified for the first time in a human patient a genetic disorder only previously described in animal models.

21 Sep 2018

Cell Medica successfully doses first patient with CMD-501 targeting pediatric neuroblastoma

Cell Medica announces the treatment of the first patient world-wide to receive CMD-501, an autologous CAR-NKT therapy targeting pediatric neuroblastoma

20 Sep 2018

TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal

As part of a national initiative to solve children's diseases, the Translational Genomics Research Institute and the Pacific Pediatric Neuro-Oncology Consortium are participating in the launch of the Kids First Data Resource Portal, which is supported by the National Institutes of Health .

19 Sep 2018

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Researchers develop synthetic molecules that deliver drugs to neuroblastoma

Potential new therapeutic approach identified for neuroblastoma tumors

Study describes vulnerability shared by large subset of cancer cell lines

Proton therapy shows excellent outcomes, minimal side effects in high-risk neuroblastoma patients

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Causes of disease including infant cancer can be revealed with new tool from Princeton University research team

New tool uncovers molecular causes of different diseases

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

New research uncovers crucial link between polyamines and MYCN

Researchers gain new insights into pediatric tumors

UC San Diego professor receives NCI Outstanding Investigator Award for cancer research

UCR postdoctoral researcher wins prestigious NIH fellowship to study neural crest cells

Researchers reveal how some cancers trick healthy cells into protecting tumors

Scientists harness power of natural killer cells to treat children with neuroblastoma

New hope for children with aggressive form of cancer

Scientists identify new biomarker for Alzheimer's disease of sporadic origin

Study using DFMO shows positive results for children with high risk neuroblastoma

Researchers identify new genetic disorder in a human patient

Cell Medica successfully doses first patient with CMD-501 targeting pediatric neuroblastoma

TGen and PNOC take part in launch of NIH-supported Kids First Data Resource Portal

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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