Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

To successfully infect its host, the rabies virus must move from the nerve ending to the nerve cell body where it can replicate.

24 Aug 2018

Researchers develop gene expression predictor for immunotherapy response in melanoma

In a new study, researchers developed a gene expression predictor that can indicate whether melanoma in a specific patient is likely to respond to treatment with immune checkpoint inhibitors, a novel type of immunotherapy.

20 Aug 2018

Study reveals how socioeconomic status affects racial, ethnic disparities in childhood cancer survival

A new study provides insights into the degree to which socioeconomic status explains racial and ethnic disparities in childhood cancer survival.

20 Aug 2018

Beat Childhood Cancer consortium's clinical trial offers new hope to children in Canada

Children in Canada who are battling neuroblastoma, a form of cancer, have been granted new hope toward a better prognosis and long-term survival.

8 Aug 2018

New CAR T-cell immunotherapy trial targets solid tumors

Seattle Children's has opened a chimeric antigen receptor (CAR) T-cell immunotherapy trial for children and young adults with relapsed or refractory non-central nervous system EGFR-expressing solid tumors. In the phase 1 trial, STRIvE-01, cancer-fighting CAR T cells will target the EGFR protein expressed in many childhood sarcoma, kidney and neuroblastoma tumors.

7 Aug 2018

Fluorescent zebrafish genes provide clues about neuroblastoma

Researchers have created transgenic zebrafish that could help them understand how neuroblastoma, a common pediatric cancer, develops.

10 Jul 2018

Fluorescent fish could help find origins of neuroblastoma

A new type of zebrafish that produces fluorescent tags in migratory embryonic nerve precursor cells could help a Rice University neurobiologist and cancer researcher find the origins of the third-most common pediatric cancer in the U.S.

10 Jul 2018

Scientists create predictive model for neuroblastoma that incorporates early developmental signals

Neuroblastoma, a rare childhood cancer of the sympathetic nervous system, is particularly deadly because it is difficult to detect and thus generally advanced before treatment begins.

9 Jul 2018

Salk Institute scientists receive funding for cancer research

Salk Institute scientists Ronald Evans, Diana Hargreaves, Tony Hunter, Graham McVicker and Geoffrey Wahl are among the first wave of researchers to receive funding from Padres Pedal the Cause, one of one of the largest stand-alone cancer fundraising events in San Diego.

27 Jun 2018

New nuclear medicine approach shows potential for precision treatment of solid tumors

A novel nuclear medicine approach is showing great promise for precision treatment of solid tumors in many types of cancer--including lung, breast, pancreas and ovarian in adults and glioma, neuroblastoma and sarcoma in children.

26 Jun 2018

Pediatric neuroblastoma patients have high risk of long-term psychological impairment

A new study reveals that pediatric neuroblastoma patients are at elevated risk for long-term psychological impairment. In addition, those who experience such impairment as they get older tend to require special education services and to not go on to college.

11 Jun 2018

Study identifies four tumor survival strategies in childhood cancer

Researchers have identified four main trajectories for the development of childhood cancer, two of which have been linked to disease relapse.

5 Jun 2018

Study shows four survival strategies of tumor cells in childhood cancer

Cancer cells in children tend to develop by following four main trajectories - and two of them are linked to relapse of the disease, research led by Lund University in Sweden shows.

5 Jun 2018

Anti-inflammatory strategy could lead to improved survival of children with neuroblastoma

Researchers at Karolinska Institutet and Karolinska University Hospital have discovered that an anti-inflammatory drug candidate inhibiting the prostaglandin E2 producing enzyme mPGES-1 in the tumor stroma reduces tumor growth in experimental neuroblastoma models.

28 May 2018

Study: Gadolinium deposition in brain not associated with dosage

Investigators at Children's Hospital Los Angeles have determined that in children receiving gadolinium as a contrast agent to enhance MRI examinations, signal changes attributed solely to deposition of this material in the brain are not dependent on the amount of gadolinium administered but rather these changes are seen in association with other factors such as the presence of brain tumors and treatment using brain irradiation. Results of the study were just published in the journal, Radiology.

15 May 2018

New combination therapy could improve survival in children with high-risk neuroblastoma

Investigators at the Children's Center for Cancer and Blood Diseases at Children's Hospital Los Angeles provide preclinical evidence that the presence of tumor-associated macrophages--a type of immune cell--can negatively affect the response to chemotherapy against neuroblastoma.

25 Apr 2018

Maternal obesity and androgen excess induce sex-specific anxiety in offspring, study suggests

Maternal obesity and androgen excess induce sex-specific anxiety in the offspring, according to a study on mice by researchers at Karolinska Institutet in Sweden published in The FASEB Journal.

22 Mar 2018

Study identifies two new biomarkers for common form of childhood cancer

Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, and eventually also for treatment.

13 Mar 2018

Zika virus could be alternative for treatment of aggressive brain cancer

Zika virus, feared for causing microcephaly in babies whose mothers were infected during pregnancy by attacking the cells that will give rise to the fetus's cerebral cortex, could be an alternative for treatment of glioblastoma, the most common and aggressive kind of malignant brain tumor in adults.

21 Feb 2018

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

Several childhood cancer cell types show features of immature neural cells, and there is evidence suggesting that these tumors may arise from neural crest stem cells that underwent abnormal changes during embryonic development.

20 Feb 2018

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Drug used to treat amoebic dysentery may block journey of rabies virus in nerves

Researchers develop gene expression predictor for immunotherapy response in melanoma

Study reveals how socioeconomic status affects racial, ethnic disparities in childhood cancer survival

Beat Childhood Cancer consortium's clinical trial offers new hope to children in Canada

New CAR T-cell immunotherapy trial targets solid tumors

Fluorescent zebrafish genes provide clues about neuroblastoma

Fluorescent fish could help find origins of neuroblastoma

Scientists create predictive model for neuroblastoma that incorporates early developmental signals

Salk Institute scientists receive funding for cancer research

New nuclear medicine approach shows potential for precision treatment of solid tumors

Pediatric neuroblastoma patients have high risk of long-term psychological impairment

Study identifies four tumor survival strategies in childhood cancer

Study shows four survival strategies of tumor cells in childhood cancer

Anti-inflammatory strategy could lead to improved survival of children with neuroblastoma

Study: Gadolinium deposition in brain not associated with dosage

New combination therapy could improve survival in children with high-risk neuroblastoma

Maternal obesity and androgen excess induce sex-specific anxiety in offspring, study suggests

Study identifies two new biomarkers for common form of childhood cancer

Zika virus could be alternative for treatment of aggressive brain cancer

Researchers target abnormal epigenetic mechanisms involved in childhood cancers

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Neuroblastoma News and Research

Latest Neuroblastoma News and Research

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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