Neurology News and Research

Latest Neurology News and Research

Epilepsy experts discuss on new NTI definition, bioequivalence guidelines at AES annual meeting

For several years, epilepsy practitioners have questioned the U.S. Food and Drug Administration's definition of bioequivalence as it applies to narrow therapeutic index drugs, such as those used for epilepsy. In response to these concerns, the FDA has sponsored 3 studies of antiepileptic drugs and also convened an advisory board to help determine which drugs are NTI.

10 Dec 2013

Exercise program improves symptoms of depression in patients with Parkinson's disease

A new study by a movement disorder neurologist at The Ohio State University Wexner Medical Center found that depression improved among patients with Parkinson's disease who participated in a long-term group exercise program.

10 Dec 2013

Study offers new insight into benefits of vitamin D in people with multiple sclerosis

In mice with a rodent form of multiple sclerosis (MS), vitamin D appears to block damage-causing immune cells from migrating to the central nervous system, offering a potential explanation for why the so-called "sunshine vitamin" may prevent or ease symptoms of the neurodegenerative disease, according to results of a study at Johns Hopkins.

9 Dec 2013

Study demonstrates safety and efficacy of NeuroPace RNS System in adults with intractable seizures

Researchers present the findings from a 2-year multicenter randomized double blinded controlled clinical study and a 7 year long-term treatment study of the NeuroPace RNS System at the American Epilepsy Society's 67th Annual Meeting.

9 Dec 2013

Underlying loss of awareness during partial seizures is same as deep sleep

Epilepsy patients with complex partial seizures have impaired consciousness during seizure episodes and typically have no memory of the event. However, the mechanisms of seizure unconsciousness are unclear.

9 Dec 2013

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Why do certain Alzheimer medications work in animal models but not in clinical trials in humans? A research team from the University of Bonn and the biomedical enterprise LIFE & BRAIN GmbH has been able to show that results of established test methods with animal models and cell lines used up until now can hardly be translated to the processes in the human brain.

9 Dec 2013

Downregulation of caveolin-1 contributes to synaptic plasticity deficit in hippocampus of aged rats

Caveolin-1 may be a new target for interfering with age-dependent decline in synaptic plasticity. To explore the relationship between synaptic plasticity in the aging process and changes in learning and memory, Dr. Yang Liu and coworkers from the First Affiliated Hospital, Dalian Medical University, China examined synaptophysin expression in the hippocampus, cortex and cerebellum of rats at different ages, and analyzed the association between synaptophysin expression and cognition and behaviors.

9 Dec 2013

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

6 Dec 2013

Study reveals that brain cancer cells resist therapy by dialing down gene mutation targeted by drugs

A team of scientists, led by principal investigator Paul S. Mischel, MD, a member of the Ludwig Institute for Cancer Research and professor in the Department of Pathology at the University of California, San Diego School of Medicine, has found that brain cancer cells resist therapy by dialing down the gene mutation targeted by drugs, then re-amplify that growth-promoting mutation after therapy has stopped.

6 Dec 2013

Alvotech to invests $250M in the development of biosimilar monoclonal antibodies

Alvotech, a powerful new player in the field of biopharmaceuticals, today announced plans to invest $250 million in the development and manufacturing of a portfolio of biosimilar monoclonal antibodies.

5 Dec 2013

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

Subthalamic nucleus deep brain stimulation can significantly improve the motor features of the Parkinson's disease in carefully selected patients. However, effects of subthalamic nucleus deep brain stimulation on the social adjustment, coping strategies and mental health-related quality of life of these patients remain unclear.

5 Dec 2013

TLR4 antibody-mediated signaling system in apoptosis of hippocampal neurons

Toll-like receptor 4 (TLR4) antibody, protein kinase B (AKT) inhibitor, LY 294002, and glycogen synthase kinase 3β (GSK-3β) inhibitor, LiCl, were used by Yu He and colleagues from Nantong University, China to attenuate or augment the effects of the TLR4-phosphatidylinositol 3 kinase (PI3K)/AKT-GSK-3β signaling pathway so as to identify the participation of this signaling system in the apoptosis of hippocampal neurons.

5 Dec 2013

TB vaccine may help prevent multiple sclerosis

A vaccine used to prevent tuberculosis in other parts of the world may help prevent multiple sclerosis in people who show the beginning signs of the disease, according to a new study published in the December 4, 2013, online issue of Neurology, the medical journal of the American Academy of Neurology.

5 Dec 2013

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

In an effort to lower medical costs, identify patients at risk for injury, and speed patient recovery, scientists will attempt to identify a molecular signal that indicates severity of brain-injury during a $4 million, five-year federal grant to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix Children's Hospital and the Translational Genomics Research Institute (TGen).

5 Dec 2013

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Los Angeles residents Selim Zilkha and Mary Hayley are raising the stakes in the fight against Alzheimer's disease, the only cause of death among the top 10 in the United States that cannot currently be prevented, cured or slowed.

4 Dec 2013

Lord Walton of Detchant receives honorary degree from Northumbria University

Northumbria University, Newcastle has today awarded Lord Walton of Detchant with an honorary degree in recognition of his long career as a world-leading neurologist.

4 Dec 2013

18F-FDOPA imaging can help distinguish radiation-induced lesions in patients with brain metastases

Imaging with the molecular imaging tracer 18F-FDOPA can help distinguish radiation-induced lesions from new tumor growth in patients who have been treated with radiation for brain metastases, according to new research published in The Journal of Nuclear Medicine. Using this amino acid tracer, researchers found that physicians could accurately differentiate the two types of lesions 83 percent of the time. Progression-free survival could also be predicted through evaluating the 18F-FDOPA imaging results.

4 Dec 2013

USPTO awards patent to Sanovas' Abrading Balloon Catheter for Extravasated Drug Delivery

Sanovas, Inc., (www.sanovas.com) a life science technology company focused on developing and commercializing next generation micro-invasive diagnostics, devices and drug delivery technologies announced today that the United States Patent and Trademark Office issued patent # 8,597,239 for the company's Abrading Balloon Catheter for Extravasated Drug Delivery.

4 Dec 2013

UH Rainbow receives Top Children's Hospital distinction from Leapfrog Group

University Hospitals Rainbow Babies & Children's Hospital (UH Rainbow) is one of only 13 children's hospitals in the country - and the only one in northern Ohio - to receive the Top Children's Hospital distinction from The Leapfrog Group.

4 Dec 2013

California scholar receives Wrawemeyer Award for Psychology for proposed somatic marker hypothesis

A California scholar who proposed that emotions play an integral role in human reasoning and decision-making has won the 2014 University of Louisville Grawemeyer Award for Psychology.

4 Dec 2013

Neurology News and Research

Latest Neurology News and Research

Epilepsy experts discuss on new NTI definition, bioequivalence guidelines at AES annual meeting

Exercise program improves symptoms of depression in patients with Parkinson's disease

Study offers new insight into benefits of vitamin D in people with multiple sclerosis

Study demonstrates safety and efficacy of NeuroPace RNS System in adults with intractable seizures

Underlying loss of awareness during partial seizures is same as deep sleep

Bonn researchers use reprogrammed neurons for drug testing in Alzheimer patients

Downregulation of caveolin-1 contributes to synaptic plasticity deficit in hippocampus of aged rats

Scientists test affected human nerve cells to foretell efficacy of Alzheimer drugs

Study reveals that brain cancer cells resist therapy by dialing down gene mutation targeted by drugs

Alvotech to invests $250M in the development of biosimilar monoclonal antibodies

Neurosurgery in Parkinson's disease: Social adjustment, quality of life and coping strategies

TLR4 antibody-mediated signaling system in apoptosis of hippocampal neurons

TB vaccine may help prevent multiple sclerosis

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

Philanthropist pledges $5M to fund new endowed chair in Alzheimer's disease research at Keck School

Lord Walton of Detchant receives honorary degree from Northumbria University

18F-FDOPA imaging can help distinguish radiation-induced lesions in patients with brain metastases

USPTO awards patent to Sanovas' Abrading Balloon Catheter for Extravasated Drug Delivery

UH Rainbow receives Top Children's Hospital distinction from Leapfrog Group

California scholar receives Wrawemeyer Award for Psychology for proposed somatic marker hypothesis

Everything you need to know about epilepsy eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

Neurology News and Research

Latest Neurology News and Research

Everything you need to know about epilepsy eBook

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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