Obesity News and Research

Latest Obesity News and Research

Intarcia Therapeutics announces positive top-line results from ITCA 650 Phase 3 FREEDOM-2 clinical trial

Intarcia Therapeutics, Inc. today announced positive top-line results from its 52-week Phase 3 FREEDOM-2 clinical trial to determine the comparative efficacy of the company's late-stage investigational candidate ITCA 650 to Merck's Januvia in reducing HbA1c in patients with type 2 diabetes following a year of treatment.

18 Aug 2015

Muscle mass appears to ward off bad cardiovascular effects of obesity

Even without losing fat, more muscle appears to go a long way in fighting off the bad cardiovascular effects of obesity. That emerging evidence has scientists looking hard for new targets to uncouple the unhealthy relationship between fat and cardiovascular disease.

18 Aug 2015

Calorie control is key to losing or maintaining weight

Physical activity has many health benefits, ranging from reducing the risk of heart disease, diabetes and cancer to improving mental health and mood.

18 Aug 2015

Kentucky researcher awarded NCI grant to study potential link between obesity and breast cancer

The National Cancer Institute recently awarded a $750,000 grant to University of Kentucky researcher Fredrick Onono to study the potential link between obesity and breast cancer.

14 Aug 2015

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

The National Institutes of Health has awarded $2.7 million to the Women's Medicine Collaborative to study the placenta and its function to determine whether changes in the placenta are linked to sleep abnormalities.

14 Aug 2015

ORBERA Managed Weight Loss System receives final approval from FDA

The ORBERA Managed Weight Loss System received its final approval on Wednesday, August 5th and Ultimate Bariatrics is proud to be one of the first in the country to offer this new tool in helping people achieve their weight loss goals. Ultimate Bariatrics is excited to share that the U.S. Food and Drug Administration has approved ORBERA, a safe and effective weight loss solution with 20 years of global experience and real world results.

14 Aug 2015

UC San Diego researchers discover cells that regenerate better liver tissue than ordinary liver cells

The mechanisms that allow the liver to repair and regenerate itself have long been a matter of debate. Now researchers at University of California, San Diego School of Medicine have discovered a population of liver cells that are better at regenerating liver tissue than ordinary liver cells, or hepatocytes.

14 Aug 2015

Low-fat diets better than low-carb diets for weight loss, NIH study finds

In a recent study, restricting dietary fat led to body fat loss at a rate 68 percent higher than cutting the same number of carbohydrate calories when adults with obesity ate strictly controlled diets. Carb restriction lowered production of the fat-regulating hormone insulin and increased fat burning as expected, whereas fat restriction had no observed changes in insulin production or fat burning.

14 Aug 2015

Improved method for building proteins into antibodies

Some proteins exist so fleetingly in the bloodstream that they can't be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute (TSRI) has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

Maximum weight gain seen in obese smokers, heavy smokers after smoking cessation

For smokers, the number of cigarettes smoked per day and current body mass index are predictive of changes in weight after quitting smoking, according to researchers at Penn State College of Medicine.

14 Aug 2015

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

Some proteins exist so fleetingly in the bloodstream that they can’t be given effectively as therapies. However, building them into larger proteins, such as antibodies, can make them persist long enough to be useful. Now a team led by scientists at The Scripps Research Institute has devised an improved method for accomplishing this protein-engineering feat.

14 Aug 2015

Rhythm Metabolic completes $40 million Series A financing

Rhythm announced today the completion of a $40 million Series A financing for its subsidiary, Rhythm Metabolic, Inc., which is developing setmelanotide (RM-493), a novel peptide MC4 agonist for the treatment of obesity caused by genetic deficiencies in the MC4 pathway.

13 Aug 2015

Children who consume higher ratio of PUFAs have more lean mass, less body fat

The results of a recent study show that children who report eating more polyunsaturated fatty acids (PUFAs), found in tree nuts, seeds and fatty fish, and consume a higher ratio of PUFA: saturated fatty acids (SFAs), have more lean body mass, lower percent body fat, and less intra-abdominal fat (belly fat).

13 Aug 2015

Five sun-blocking superheroes teach preschoolers about sun safety

Five globe-trotting, sun-blocking superheroes teach preschoolers about lifelong sun safety in a new curriculum available this summer based on research at The University of Texas MD Anderson Cancer Center.

13 Aug 2015

High-protein breakfast prevents body fat gains, stabilizes glucose levels among overweight teens

Approximately 60 percent of young people habitually skip breakfast up to four times a week, previous research has shown. Although health experts recommend breakfast as a strategy to reduce an individual's chance of obesity, little research has examined if the actual type of breakfast consumed plays a significant role in one's health and weight management.

13 Aug 2015

CrystalGenomics signs agreement with Dong-A ST for commercialization of Acelex (polmacoxib) in Korea

CrystalGenomics, Inc. has announced that it has signed a Sales and Marketing Agreement with Dong-A ST Co., Ltd. for the commercialization of Acelex (polmacoxib) in Korea.

13 Aug 2015

Researchers elucidate mechanism that induces skeletal muscle atrophy in patients with congestive heart failure

It is a paradox: Patients with advanced congestive heart failure lose skeletal muscle mass, but their heart muscles become enlarged to provide the body with an adequate supply of blood and thus with oxygen. It has long been known that the protein angiotensin II plays a villainous role in this process, but the exact mechanism has remained unclear.

12 Aug 2015

Gastric bypass surgery enhances energy expenditure

Gastric bypass surgery often leads to a sustained weight loss. Researchers at Sahlgrenska Academy have found part of the explanation: the operation enhances energy expenditure such that eating actually helps the person lose weight.

12 Aug 2015

Testosterone administration not associated with atherosclerosis progression among older men

Among older men with low testosterone levels, testosterone administration for 3 years compared with placebo did not result in a significant difference in the rates of change in atherosclerosis (thickening and hardening of artery walls), nor was it associated with improved overall sexual function or health-related quality of life, according to a study in the August 11 issue of JAMA.

12 Aug 2015

$Breakdown of fibrin protein essential for bone fracture repair$

Breakdown of fibrin protein essential for bone fracture repair

A team of Vanderbilt investigators has discovered that fibrin, a protein that was thought to play a key role in fracture healing, is not required. Instead, the breakdown of fibrin is essential for fracture repair.

12 Aug 2015

Obesity News and Research

Latest Obesity News and Research

Intarcia Therapeutics announces positive top-line results from ITCA 650 Phase 3 FREEDOM-2 clinical trial

Muscle mass appears to ward off bad cardiovascular effects of obesity

Calorie control is key to losing or maintaining weight

Kentucky researcher awarded NCI grant to study potential link between obesity and breast cancer

Women's Medicine Collaborative awarded NIH grant to study link between placenta and sleep abnormalities

ORBERA Managed Weight Loss System receives final approval from FDA

UC San Diego researchers discover cells that regenerate better liver tissue than ordinary liver cells

Low-fat diets better than low-carb diets for weight loss, NIH study finds

Improved method for building proteins into antibodies

Maximum weight gain seen in obese smokers, heavy smokers after smoking cessation

TSRI-led team devises selection-based, protein-engineering method to work on obesity therapy

Rhythm Metabolic completes $40 million Series A financing

Children who consume higher ratio of PUFAs have more lean mass, less body fat

Five sun-blocking superheroes teach preschoolers about sun safety

High-protein breakfast prevents body fat gains, stabilizes glucose levels among overweight teens

CrystalGenomics signs agreement with Dong-A ST for commercialization of Acelex (polmacoxib) in Korea

Researchers elucidate mechanism that induces skeletal muscle atrophy in patients with congestive heart failure

Gastric bypass surgery enhances energy expenditure

Testosterone administration not associated with atherosclerosis progression among older men

Breakdown of fibrin protein essential for bone fracture repair

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

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Obesity News and Research

Latest Obesity News and Research

Todd Bauman and Chris Povich

Scaling organ‑chip technology for human‑relevant drug discovery

Unlocking drug amorphization: Continuous, solvent-free twin screw granulation

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