Obesity

Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.

Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.

What is Obesity?

Obesity and overweight have in the last decade become a global problem - according to the World Health Organization (WHO) back in 2005 approximately 1.6 billion adults over the of age 15+ were overweight, at least 400 million adults were obese and at least 20 million children under the age of 5 years were overweight.

Obesity and Anesthesia

Obesity and Diabetes

Obesity and Depression

Obesity and Stress

Obesity Epidemiology

Why is Visceral Fat Dangerous?

Obesity and Respiratory Disorders

Causes of Obesity and Overweight

Obesity and Sleep

What does Sleeve Gastrectomy Involve?

Obesity in Adults

See more featured articles »

Obesity in Children

Obesity and Fractures

Obesity and Sexual Health

Obesity and Cancer

Abdominal Obesity and the Metabolic Syndrome

Obesity and Genetics

Obesity and Periodontitis

What is Obesity Paradox?

Obesity Management

Obesity and Infertility

Obesity and Metabolic Syndrome

Obesity, What Can be Done?

Obesity and Exercise

Obesity and Blood Pressure

What is Body Mass Index (BMI)?

Obesity and Fast Food

Obesity and Arthritis

Obesity and Skin Problems

Obesity in Pregnancy

Obesity and Hormones

Obesity and Heart Disease

Fat Mass and Obesity-Associated Gene (FTO)

Dieting for Obese Children

Obesity and Autism

Latest Obesity News and Research

Greater food variety at buffets may lead to overeating

At Super Bowl parties, weddings, Independence Day cookouts and Thanksgiving dinners, people celebrate with large spreads of food.

27 Feb 2026

How physical strength and self-belief grow together in teens

Physical fitness and psychological resilience develop side by side during adolescence, a life stage that lays the foundation for adult health. Cardiorespiratory endurance, muscular strength, and agility are well-known predictors of cardiometabolic health, while self-efficacy, defined as the belief in one's ability to overcome challenges, shapes motivation, persistence, and coping strategies.

26 Feb 2026

New review explains how circular RNAs could unlock fat browning therapies

A Cell Death & Disease review synthesizes preclinical evidence that circular RNAs regulate adipose browning and metabolic pathways through microRNA interactions, protein binding, and organelle-linked stress mechanisms. It highlights their biomarker and therapeutic potential in obesity and type 2 diabetes while underscoring key translational challenges, including delivery specificity and human validation.

26 Feb 2026

Heavy alcohol intake is associated with dangerous belly fat accumulation, large UK study shows

In a large UK population cohort, higher weekly alcohol consumption was dose-dependently associated with greater visceral fat mass measured by DXA, independent of total body fat. Heavy drinkers showed over 10% higher proportional visceral fat compared with lower consumption groups, a pattern linked to increased cardiometabolic risk.

26 Feb 2026

Neem compound gedunin shows promise against pancreatic cancer

Ramadevi Subramani Reddy, Ph.D., remembers the neem tree from her childhood in India - a plant her grandmother used to treat everything from fevers to infections.

26 Feb 2026

Organ donation after circulatory death expands transplant opportunities

Organ donation after the heart stops beating, a practice called donation after circulatory death, has gone from rare to routine in the United States, a new study shows.

26 Feb 2026

Middle-aged men most vulnerable to aging effects of new PFAS

Per- and polyfluoroalkyl substances (PFAS) – 'forever chemicals' in common parlance – are a class of thousands of synthetic chemicals often used in non-stick coatings, water-resistant fabrics, fire-fighting foams, food packages, cleaning products, and plastics.

26 Feb 2026

Easy-to-use blood test score can help identify alcohol-related fatty liver disease

Researchers at University of California San Diego School of Medicine have developed a new, easy-to-use blood test score that can help identify when fatty liver disease is being driven by excessive alcohol use, an important distinction that often goes unrecognized in routine care.

25 Feb 2026

Nearly 6 in 10 women in the U.S. may have cardiovascular disease in the next 25 years

Driven by rising rates in high blood pressure, nearly 6 in 10 women in the U.S. will have some type of cardiovascular disease (CVD) in the next 25 years, according to a new scientific statement published today in Circulation, the peer-reviewed, flagship journal of the American Heart Association, a global force changing the future of health for all.

25 Feb 2026

Parental obesity before conception raises offspring fatty liver risk

Pre-pregnancy parental overweight and obesity is linked to the next generation's heightened risk of developing fatty liver disease, a potential precursor to cirrhosis and liver failure, suggests research published online in the journal Gut.

24 Feb 2026

Combined GLP-1 and GLP-2 treatment appears safe but does not beat placebo for obesity

In a 12-week randomized phase IIa trial in adults with obesity, the dual GLP-1/GLP-2 receptor agonist dapiglutide was well tolerated but did not achieve statistically significant weight loss compared with placebo at 4 mg or 6 mg doses. Although the higher dose showed modest within-group weight reduction and improved HbA1c, unexpectedly substantial placebo-associated weight loss limited the observed treatment effect.

24 Feb 2026

Tirzepatide activates brown fat, boosting metabolism beyond appetite control

Tirzepatide is one of the drugs that has revolutionized the treatment of obesity and other conditions such as diabetes in recent years.

24 Feb 2026

Early exposure to unhealthy foods leaves lasting brain and feeding changes

Eating unhealthy foods early in life leave lasting brain and feeding changes but gut bacteria can help restore healthy eating, new University College Cork (UCC) research study finds today (Tuesday 24th February 10am)

24 Feb 2026

Swiss centenarians show youthful blood protein profiles in aging study

In Switzerland, 0.02% of the population lives beyond the age of 100. Could there be biological characteristics associated with this exceptional longevity? As part of the "SWISS100" study, the first large-scale Swiss research project dedicated to centenarians, a team from the University of Geneva (UNIGE) and the University of Lausanne (UNIL) compared the blood profiles of centenarians with those of octogenarians, and then with those of individuals aged 30 to 60.

24 Feb 2026

Moderate physical activity lowers risk of sarcopenic obesity in seniors

Older people who are physically active have a significantly lower risk of developing sarcopenic obesity - a combination of obesity and weak muscles.

24 Feb 2026

Transforming obese fat cells into energy burners

Ordinary fat cells in obese animals can be induced to burn energy stores, generating substantial heat, according to a preclinical study by Weill Cornell Medicine investigators.

23 Feb 2026

WashU Medicine receives 80 million to study exceptional longevity

Researchers at Washington University School of Medicine in St. Louis have received an $80 million grant to continue research into the mysteries of exceptional longevity.

23 Feb 2026

Higher ultra-processed food intake aligns with greater binge eating risk in obesity study

Higher intake of ultra-processed foods in adults with obesity was associated with disordered eating symptoms, poorer diet quality, and lower protein intake. The cross-sectional findings suggest dietary processing level may influence eating behaviour patterns relevant to obesity management, though causality cannot be inferred.

23 Feb 2026

New review explores whether berries can slow cognitive decline linked to obesity

This systematic review in Nutrients evaluates human studies investigating whether polyphenol-rich berry consumption can modulate obesity-related metabolic dysfunction and support cognitive performance, particularly in individuals at risk of mild cognitive impairment. Evidence suggests modest memory benefits and possible metabolic improvements, although biomarker findings and long-term clinical relevance remain uncertain.

22 Feb 2026

New technique synthesizes non-natural amino acids for advanced peptide therapeutics

Ozempic has been making headlines for its remarkable success in treating obesity and diabetes. Yet it is just one in a rapidly growing class of drugs called peptide therapeutics that sits between small molecules (like aspirin) and biologics (like antibodies).

20 Feb 2026