Obesity

Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.

Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.
Metaflammation Explained: How Obesity, Diabetes, and Aging Are Connected

Obesity-associated metaflammation involves persistent, low-grade inflammation that disrupts insulin signaling and contributes to metabolic disease, with mechanisms that overlap with age-related inflammation. Weight loss and established metabolic treatments can reduce some inflammatory effects, while therapies targeting specific immune and microbial pathways remain under investigation.

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Overview

Feature Articles

Latest Obesity News and Research

More screen time, less sleep: What researchers observed in children with obesity

More screen time, less sleep: What researchers observed in children with obesity

Younger adults in America's famous Blue Zone are eating differently

Younger adults in America's famous Blue Zone are eating differently

Two healthy diets stood out in a study of more than 7,000 adults

Two healthy diets stood out in a study of more than 7,000 adults

Researchers explore why male and female brains adapt differently to overeating

Researchers explore why male and female brains adapt differently to overeating

New study links cannabis use to increased cardiovascular risk

New study links cannabis use to increased cardiovascular risk

Study links ultra-processed foods to poorer dietary quality

Study links ultra-processed foods to poorer dietary quality

From simple ovulation treatments to IVF, how doctors choose the right approach

From simple ovulation treatments to IVF, how doctors choose the right approach

Moving beyond weight loss to create truly inclusive healthcare environments

Moving beyond weight loss to create truly inclusive healthcare environments

Could GLP-1 drugs help women with PCOS beyond weight loss?

Could GLP-1 drugs help women with PCOS beyond weight loss?

Children with intense mood swings face greater risk of emotional overeating in adolescence

Children with intense mood swings face greater risk of emotional overeating in adolescence

Insilico Medicine leader shares AI-driven drug discovery insights in Shanghai and Dubai

Insilico Medicine leader shares AI-driven drug discovery insights in Shanghai and Dubai

Major studies identify accurate non-invasive tests for liver disease

Major studies identify accurate non-invasive tests for liver disease

Multivitamins boost key vitamin levels, but do they improve your health?

Multivitamins boost key vitamin levels, but do they improve your health?

Brief dietary changes may prime the immune system for inflammation

Brief dietary changes may prime the immune system for inflammation

New framework guides safer obesity drug prescribing in older adults

New framework guides safer obesity drug prescribing in older adults

Worried nuts will cause weight gain? A large review puts that concern in perspective

Worried nuts will cause weight gain? A large review puts that concern in perspective

Can broccoli sprouts help with insulin resistance? New review offers clues

Can broccoli sprouts help with insulin resistance? New review offers clues

Circadian desynchronization: The hidden cost of daylight saving time transitions

Circadian desynchronization: The hidden cost of daylight saving time transitions

Limited app use adds a twist to a nurse-led dementia risk trial

Limited app use adds a twist to a nurse-led dementia risk trial

High-fat diets in mouse parents alter offspring brain development

High-fat diets in mouse parents alter offspring brain development

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