Obesity

Overweight and obesity are defined by the WHO as abnormal or excessive fat accumulation that presents a risk to an individuals health.

Overweight and obesity are major risk factors for a number of chronic diseases, including diabetes, cardiovascular diseases and cancer and while it was once an issue only in high income countries, overweight and obesity has now dramatically risen in low- and middle-income countries.Such countries are now facing a "double burden" of disease, for while they continue to deal with the problems of infectious disease and under-nutrition, they are also experiencing a rapid upsurge in chronic disease risk factors such as obesity and overweight, particularly in urban settings.

What is Obesity?

Obesity and overweight have in the last decade become a global problem - according to the World Health Organization (WHO) back in 2005 approximately 1.6 billion adults over the of age 15+ were overweight, at least 400 million adults were obese and at least 20 million children under the age of 5 years were overweight.

Obesity and Exercise

Obesity and Stress

Obesity and Fractures

Obesity and Periodontitis

Why is Visceral Fat Dangerous?

Obesity and Sexual Health

Abdominal Obesity and the Metabolic Syndrome

Obesity and Anesthesia

Obesity in Adults

Obesity and Infertility

Obesity in Pregnancy

See more featured articles »

Obesity and Hormones

What does Sleeve Gastrectomy Involve?

Obesity Management

Obesity, What Can be Done?

Dieting for Obese Children

Fat Mass and Obesity-Associated Gene (FTO)

Obesity and Cancer

Obesity in Children

Obesity and Diabetes

Obesity and Metabolic Syndrome

Obesity and Skin Problems

Obesity and Autism

What is Obesity Paradox?

What is Body Mass Index (BMI)?

Obesity and Fast Food

Obesity and Sleep

Obesity and Depression

Obesity and Blood Pressure

Obesity and Respiratory Disorders

Obesity and Heart Disease

Causes of Obesity and Overweight

Obesity Epidemiology

Obesity and Arthritis

Obesity and Genetics

Latest Obesity News and Research

Poor lifestyle habits nearly double your chance of developing AFib

A large Framingham Heart Study analysis found that adults with poor cardiovascular health scores on the Life’s Essential 8 were nearly twice as likely to develop atrial fibrillation as those with ideal scores. Maintaining healthy lifestyle habits, especially optimal BMI, blood pressure, and glucose, may help reduce AF risk.

2 Jul 2025

Mediterranean diet wins on weight but misses on memory in diverse aging population

A 14-month randomized trial in older African American adults with obesity found that adopting a Mediterranean diet, with or without calorie-restricted weight loss, significantly improved diet quality and reduced body weight and visceral fat. However, no cognitive benefits were observed compared to usual diet.

2 Jul 2025

‘MAHA Report’ calls for fighting chronic disease, but Trump and Kennedy have yanked funding

‘MAHA report’ calls for fighting chronic disease, but Trump and Kennedy have yanked funding

2 Jul 2025

Plant-based fitness supplements for reversing metabolic syndrome

Research indicates that specific plant-based supplements, combined with exercise, can improve cardiometabolic markers in those at risk for metabolic syndrome.

2 Jul 2025

Why exercise is key for keeping slim after you quit smoking

Quitting smoking is linked to greater long-term waist circumference gain, but this effect may be due to shared genetics rather than quitting itself. Increased physical activity consistently helped limit waist expansion across all genetic backgrounds.

1 Jul 2025

Gut microbiota signatures predict gestational diabetes in first trimester

A new study has identified early-pregnancy gut microbiota signatures associated with the development of gestational diabetes mellitus, a metabolic disorder that carries substantial risks to both maternal and fetal health.

1 Jul 2025

Uterine cancer deaths expected to rise sharply in the United States by 2050

Uterine cancer incidence and mortality rates are projected to increase significantly over the next three decades in the United States, with incidence-based mortality expected to be nearly three times higher in Black women compared with white women by 2050.

1 Jul 2025

Staying active reduces waist gain after you quit smoking

Investigating smoking cessation and waist circumference, this study highlights the role of leisure-time physical activity in managing abdominal obesity.

1 Jul 2025

HHS eliminates CDC staff who made sure birth control is safe for women at risk

For Brianna Henderson, birth control isn’t just about preventing pregnancy.

1 Jul 2025

Economic downturns increase childhood malnutrition risks

Even small drops in national income can significantly increase the risk of various forms of childhood malnutrition- not only undernutrition but also overweight and obesity, shows a study led by the Barcelona Institute for Global Health (ISGlobal), an institution supported by "la Caixa" Foundation.

30 Jun 2025

Insilico Medicine begins clinical trial for AI-designed cancer drug ISM3412

Insilico Medicine, a clinical-stage biotechnology company driven by generative artificial intelligence (AI), today announces that the first patient has been dosed in a global multicenter clinical trial (NCT06414460) to evaluate ISM3412, a potentially best-in-class, AI-empowered MAT2A inhibitor with novel structure, in patients with locally advanced and metastatic solid tumors.

27 Jun 2025

Do spicy foods help or hurt your gut health?

Capsaicin, the spicy compound in chili peppers, not only influences inflammation, metabolism, and cancer risk but also shapes the gut microbiome in complex, context-dependent ways. This comprehensive review highlights both the therapeutic promise and potential risks of capsaicin, calling for deeper research into its microbiome-mediated effects.

26 Jun 2025

Can your athletic past raise your risk for atrial fibrillation?

Elite retired rowers face a nearly threefold increased risk of atrial fibrillation compared to the general population, driven by a combination of long-term cardiac remodelling and underlying polygenic genetic susceptibility.

26 Jun 2025

More people survive heart attacks but face ongoing cardiac risks

In 1970, someone over the age of 65 hospitalized for a heart attack in the United States had about a 60% chance of leaving the hospital alive. Today, the survival rate is over 90%, with even better outcomes for younger patients.

26 Jun 2025

Performance pay initially boosted GP care but gains did not last

Introducing performance related pay for UK general practices initially improved quality of care, but did not seem to provide lasting improvements beyond that expected by previous trends, finds a study published by The BMJ today.

26 Jun 2025

Experts urge shift from weight focus to patient centered care

Focusing solely on achieving weight loss for people with a high body mass index (BMI) may do more harm than good, argue experts in The BMJ today.

26 Jun 2025

Tirzepatide rewires appetite and slashes calorie intake in new obesity trial

A 6-week randomized trial found that tirzepatide significantly reduced energy intake, appetite, and cravings in adults with overweight or obesity, outperforming liraglutide and placebo. Brain imaging revealed that tirzepatide also lowered neural responses to high-fat, high-sugar food cues, offering mechanistic insight into its potent weight-loss effects.

25 Jun 2025

Higher BMI linked to slower concussion recovery in athletes and cadets

Clinicians who work with elite college athletes and military cadets should be aware of the association between higher body mass index (BMI) and worse concussion recovery, suggests new University of Pittsburgh School of Medicine research published today in Sports Medicine.

25 Jun 2025

Gut microbe emerges as a promising tool in the fight against COVID-19

Researchers found that Akkermansia muciniphila boosts lung-specific antiviral immunity against SARS-CoV-2 in mice by modulating the gut–lung axis. This commensal gut bacterium shows promise as a potential biomarker and biotherapeutic candidate for COVID-19 and other respiratory infections.

25 Jun 2025

New guidance helps GPs manage patients using weight loss drugs

Academics at King's College London and the University of East Anglia have released guidance for GPs on how to manage patients who may be privately accessing weight loss drugs.

25 Jun 2025