Obesity News and Research

Latest Obesity News and Research

Study shows why an apple a day may work differently for different people

A 12-week single-blind trial in 38 Japanese adults found that daily Fuji apple intake did not significantly change overall host metabolic markers, but responses differed by baseline gut enterotype. Participants in the Bacteroidaceae-dominant enterotype showed significant increases in fecal short-chain fatty acids after apple consumption, suggesting that gut microbiota structure may shape functional dietary responses.

13 Apr 2026

Study explains why vaccines underperform in people living with obesity

New findings reveal that obesity significantly impaired the quality and longevity of antibody responses to a Pseudomonas aeruginosa vaccine in a mouse model.

13 Apr 2026

Obesity health risks differ significantly between men and women

New research being presented at this year's European Congress on Obesity (ECO) in Istanbul, Turkey (12-15 May), reveals distinct patterns of heart, metabolic, and inflammatory health risks between men and women living with obesity, providing an insight into how clinicians may be able to tailor management approaches.

13 Apr 2026

Higher mortality risk in IBS patients using antidepressants

Research indicates that antidepressant use in IBS is linked to a 35% higher risk of all-cause mortality, highlighting safety issues with long-term treatment.

13 Apr 2026

Genetic variants may reduce effectiveness of popular diabetes drugs

More than a quarter of people with Type 2 diabetes take GLP-1 receptor agonists, but the popular diabetes drugs might not work as well for people who have certain genetic variants, according to a new study by Stanford Medicine scientists and their collaborators.

12 Apr 2026

Weight gain timing affects long-term health outcomes

When in life we gain weight can have a significant impact on our health many years later. In a study involving over 600,000 people, researchers at Lund University in Sweden have investigated how changes in weight between the ages of 17 and 60 are linked to the risk of dying from various diseases

11 Apr 2026

Insilico Medicine launches Pharma AI Spring Kickoff 2026 webinar

As the AI era becomes increasingly shaped by foundation models, the pharmaceutical industry is entering a new phase of opportunity for discovery, design, and decision-making driven by AI for science.

10 Apr 2026

Extracellular vesicles from menstrual blood cells show potential to stimulate cartilage repair

New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration.

10 Apr 2026

Popular sweeteners may impact metabolism across generations

When you choose a diet version of your favorite fizzy drink, you consume non-nutritive sweeteners, which taste sweet but - unlike sugar - contain no calories.

10 Apr 2026

GLP-1 and dual GLP-1 / GIP drugs help lose body fat while preserving lean mass

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) shows that patients using GLP-1 or combined GLP-1 / GIP receptor agonist therapy for weight loss experienced minimal lean muscle mass loss as they lost weight across 6 months of treatment.

10 Apr 2026

More steps cut chronic disease risk but cannot fully undo long sitting

Research shows higher daily step counts can mitigate risks of chronic diseases linked to prolonged sitting, emphasizing the need to reduce sedentary time.

10 Apr 2026

Study finds nutritional risks in users of GLP-1 drugs

Adults with overweight or obesity taking the new generation of weight loss drugs semaglutide and tirzepatide tend to eat significantly less, leaving them vulnerable to nutritional deficiencies, according to one of the first real-world studies to examine dietary behavior in people using glucagon-like peptide-1 receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) dual agonists RAs (collectively referred to as GLP-1 RAs) with the help of an AI-powered nutritional tracking app.

9 Apr 2026

Experts call for expanded Medicaid coverage to improve children’s health

As states reassess Medicaid coverage following recent federal policy changes and the end of pandemic-era protections, researchers are advocating for evidence-based health care policy reform and expanded Medicaid coverage for children.

9 Apr 2026

Genetic variants may help explain who loses more weight and who gets side effects on GLP-1 drugs

A large 23andMe-based GWAS found that common variants in GLP1R and GIPR help explain why some people lose more weight or experience more nausea and vomiting on GLP-1 drugs. The findings suggest genetics may eventually help predict who responds best to semaglutide or tirzepatide and who is more likely to develop side effects.

9 Apr 2026

AI-powered chemistry accelerates discovery of selective cancer inhibitors

Recently, the Insilico team's research entitled "An Internal Sulfur-Lone Pair Interaction Enabled the Discovery of Potential and Sub-Family Selective PKMYT1 Inhibitors" was invited for publication as a cover Feature in ChemMedChem.

9 Apr 2026

Study shows long-term weight benefits for breastfeeding mothers

Breastfeeding does not only affect your weight while you are breastfeeding. Women gain up to 6.5 kilos less on average later in life if they breastfeed for at least three months, according to a new study.

9 Apr 2026

Fat-producing enzyme identified as key driver of damage in Parkinson’s disease

A fat-producing enzyme in brain cells may play a key role in driving damage in Parkinson's disease and could offer a new target for treatment, scientists at Nanyang Technological University, Singapore (NTU Singapore) have found.

9 Apr 2026

Self-employment linked to lower heart disease risks in Hispanic women

Self-employed Hispanic women report less high blood pressure, obesity, diabetes, poor health and binge drinking compared to Hispanic women working for salary or wages, new research suggests.

8 Apr 2026

Why early-onset cancers are rising and how researchers plan to stop them

Early-onset cancers are rising worldwide, and this Cell Perspective argues that cancer prevention must move beyond static risk-factor snapshots toward life-course exposure mapping, tissue-level biology, and dynamic estimates of preventability. The authors propose three linked frameworks to speed discovery of cancer causes and translate those findings into more precise prevention and interception strategies.

8 Apr 2026

Long-term excess weight is a stronger predictor of cardiovascular risk

Obesity is a known risk factor for cardiovascular disease, but people's weights can shift over time, and little is known about the cumulative impact of excess weight.

8 Apr 2026