Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

Safeguard Scientifics second-quarter aggregate revenue of partner companies increase 47% to $91.6 million

Safeguard Scientifics, Inc., a holding company that builds value in growth-stage life sciences and technology companies, today announced that aggregate revenue of its partner companies for the three months ended June 30, 2010 was $91.6 million, up 47% from $62.3 million for the same partner companies in the same period of 2009. For the six months ended June 30, 2010, the aggregate partner company revenue was $176.9 million, up 45% from $121.8 million for the same partner companies for the same period of 2009.

29 Jul 2010

Scientists identify new targets to develop treatment for HD

Scientists at the Buck Institute for Age Research have discovered that a particular family of enzymes are involved in the breakdown of proteins that modify the production of toxic fragments that lead to the pathology of Huntington's disease. These enzymes, matrix metalloproteinases, provide new targets for drug therapies for the disease - targets that have already been shown to respond to cancer drugs currently in clinical development.

29 Jul 2010

REM sleep behavior disorder may later lead to neurologic disorders

A new study shows that a sleep disorder may be a sign of dementia or Parkinson's disease up to 50 years before the disorders are diagnosed. The research is published in the July 28, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology.

29 Jul 2010

Loss of key nerve cells cause Parkinson's disease: Research

Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson's disease. This discovery not only may explain how a genetic mutation linked to Parkinson's causes the cells' death, but could also open the door to new therapeutic approaches for the malady.

29 Jul 2010

Scientists study mutant protein lump formation process to control brain cell death

Australian scientists have identified the behaviour of the mutant protein 'huntingtin' which leads to the fatal Huntington's disease providing potential targets to treat the disease, a University of Melbourne study reveals.

29 Jul 2010

Research on method to open blood-brain barrier for safe cancer drug delivery

One of the human body's most powerful defensive tools, the blood-brain barrier is a chemical labyrinth that prevents toxins and viruses in the bloodstream from reaching the brain. This foolproof security system, however, limits the ability of physicians to deliver drugs directly to the brain, making it difficult to treat brain tumors. Researchers at Rensselaer Polytechnic Institute are endeavoring to solve this problem by investigating new methods for bypassing the blood-brain barrier and combating the spread of brain cancer.

28 Jul 2010

NIH issues SBIR grant to Titan Pharmaceutical for PD treatment development

Titan Pharmaceuticals, Inc. today announced that the National Institutes of Health has awarded the company a grant under the Small Business Innovation Research program supporting the development of a long-term, non-fluctuating dopamine agonist treatment for Parkinson's disease. The first year award in the amount of $300,000 will be available to Titan starting August 1, 2010, and an additional $195,000 for the second year starting August 1, 2011 has been recommended subject to availability of funds and satisfactory progress of the project. The grant will be administered by the National Institute of Neurological Disorders and Stroke.

27 Jul 2010

Epilepsy drugs analyzed for causing increased risk of suicide in patients

While the Food and Drug Administration requires a warning of an increased risk of suicide for all epilepsy drugs, a new study shows that only certain drugs may increase the risk. The study is published in the July 27, 2010, issue of Neurology, the medical journal of the American Academy of Neurology. Newer drugs with a higher risk of causing depression than other epilepsy drugs, such as levetiracetam, topiramate and vigabatrin, were found to increase the risk of self-harm or suicidal behavior among people with epilepsy.

27 Jul 2010

Research reveals molecular basis of neural circuits

The basal ganglia is a series of highly connected brain areas localised deep in the cerebral cortex that recently has attracted interest of neuroscientists when it was linked to learning, and discovered to be affected in a number of disorders of the addictive and obsessive spectrum, but also in Parkinson's disease (PD). And now researchers think they have understood why as they found that neurons in this area signal the beginning and the end of voluntary actions. In fact, problems in these neurons could explain the "incapacity to stop" seen in obsession or compulsive behaviour, but also the problems in learning and control of movement characteristic of Parkinson's

26 Jul 2010

Preclinical data of new acamprosate prodrug to be presented at International Fragile X Conference

XenoPort, Inc. announced today that it has discovered a novel prodrug that has the potential to improve significantly the blood concentration of acamprosate compared with the currently approved formulation of acamprosate. Preclinical data on this new product candidate will be presented tomorrow at the National Fragile X Foundation's 12th International Fragile X Conference in Detroit, Michigan.

23 Jul 2010

Research on new treatments for FXS to be presented at International Fragile X Conference

Accelerated research findings leading to potentially significant new treatments for fragile X syndrome will be presented to nearly 1,000 family members and professionals at the 12th International Fragile X Conference in Dearborn July 21-25.

23 Jul 2010

Major breakthrough in Alzheimer's disease research

Researchers from the University of Sydney's Alzheimer's and Parkinson's Disease Laboratory have achieved a major breakthrough by finding the causes of Alzheimer's disease at a cellular level and thereby identifying a potential therapy as a result.

23 Jul 2010

Protein parkin essential for hypothalamic neurons recovery in Parkinson's disease patients

A Michigan State University researcher is working to uncover how a protein known as parkin may help nerve cells fight off damage from Parkinson's disease, a strategy that could lead to new therapies for the degenerative ailment.

23 Jul 2010

Baxter second-quarter global sales increase 2% to $3.2 billion

Baxter International Inc. today announced its financial results for the second quarter of 2010, reporting earnings in line with the company's previously issued guidance of $0.90 to $0.93 per diluted share.

From Baxter International Inc. 22 Jul 2010

Brain neuron activity can signal initiation, termination of behavioural sequences: Study

Rui Costa, Principal Investigator of the Champalimaud Neuroscience Programme at the Instituto Gulbenkian de Ciência, and Xin Jin, of the National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, describe in the latest issue of the journal Nature, that the activity of certain neurons in the brain can signal the initiation and termination of behavioural sequences we learn anew. Furthermore, they found that this brain activity is essential for learning and executing novel action sequences, many times compromised in patients suffering from disorders such as Parkinson's or Huntington's.

22 Jul 2010

AHAF enters new partnership with BioMed Central's Molecular Neurodegeneration journal

The American Health Assistance Foundation (AHAF) today announced a new partnership with BioMed Central's open access journal, Molecular Neurodegeneration (MN) in which the publication will be the official open access journal of AHAF.

21 Jul 2010

Researchers reveal findings on restricted lineage of iPS cells

Adult cells that have been reprogrammed into induced pluripotent stem cells (iPS cells) do not completely let go of their past, perhaps limiting their ability to function as a less controversial alternative to embryonic stem cells for basic research and cell replacement therapies, according to researchers at Children's Hospital Boston, John Hopkins University and their colleagues

20 Jul 2010

Researchers use bioelectric signals of brain to detect neurodegenerative diseases

A group of researchers from Universidad Carlos III de Madrid has presented a new algorithm that uses a new method to analyse the information obtained from electroencephalograms to detect neurodegenerative diseases, such as epilepsy, using the bioelectric signals of the brain.

20 Jul 2010

Parkinson's medication produces serious side effects in the form of involuntary, jerky movements: Research

One in every 100 elderly people suffers from Parkinson's disease, a disease of the nervous system with symptoms including stiffness and shaking. The standard medication used to treat Parkinson's is Levodopa, a drug that initially has major benefits but can later also produce serious side effects in the form of involuntary, jerky movements. A research group at Lund University has now found a way to study what it is in the brain that causes these side effects.

20 Jul 2010

ArmaGen uses BBB molecular Trojan horse platform technology to create brain penetrating form of human EPO

Human erythropoietin (EPO) is a potent neuroprotective agent for multiple brain disorders, including stroke, brain and spinal cord injury, and Parkinson's disease. However, EPO drug development for the brain is limited, because EPO does not cross the blood-brain barrier (BBB). In acute stroke or brain injury, the BBB is intact in the early hours after the insult when neuroprotection is still possible. Therefore, large molecule biopharmaceuticals such as EPO must be re-engineered to enable BBB transport.

17 Jul 2010

Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

Safeguard Scientifics second-quarter aggregate revenue of partner companies increase 47% to $91.6 million

Scientists identify new targets to develop treatment for HD

REM sleep behavior disorder may later lead to neurologic disorders

Loss of key nerve cells cause Parkinson's disease: Research

Scientists study mutant protein lump formation process to control brain cell death

Research on method to open blood-brain barrier for safe cancer drug delivery

NIH issues SBIR grant to Titan Pharmaceutical for PD treatment development

Epilepsy drugs analyzed for causing increased risk of suicide in patients

Research reveals molecular basis of neural circuits

Preclinical data of new acamprosate prodrug to be presented at International Fragile X Conference

Research on new treatments for FXS to be presented at International Fragile X Conference

Major breakthrough in Alzheimer's disease research

Protein parkin essential for hypothalamic neurons recovery in Parkinson's disease patients

Baxter second-quarter global sales increase 2% to $3.2 billion

Brain neuron activity can signal initiation, termination of behavioural sequences: Study

AHAF enters new partnership with BioMed Central's Molecular Neurodegeneration journal

Researchers reveal findings on restricted lineage of iPS cells

Researchers use bioelectric signals of brain to detect neurodegenerative diseases

Parkinson's medication produces serious side effects in the form of involuntary, jerky movements: Research

ArmaGen uses BBB molecular Trojan horse platform technology to create brain penetrating form of human EPO

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Parkinson's Disease News and Research

Latest Parkinson's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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