Pharmacology News and Research

Latest Pharmacology News and Research

Targeting specific signaling pathway could provide new avenue for treating fetal alcohol syndrome

Fetal alcohol spectrum disorders are an array of conditions that can occur in a person whose mother consumed alcohol during pregnancy. Fetal alcohol syndrome, the most severe of these conditions, often results in physical abnormalities, behavioral development issues and intellectual disabilities.

24 Oct 2018

New partnership aims to tackle cancer health disparities

Although cancer affects all populations in the United States, certain ethnic populations bear a disproportionate burden of cancer compared with other groups, according to the National Cancer Institute.

23 Oct 2018

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

With a pair of RO1 grants from the National Institutes of Health, pain researcher Daniela Salvemini, Ph.D., will embark on two new research projects, studying chemotherapy-induced cognitive impairment, or "chemo brain," symptoms and unwanted side effects of opioids.

23 Oct 2018

Study: Targeting specific genomic mutation in breast cancer improves survival

Targeting a common mutation in patients with hormone receptor positive (HR+) HER2 negative (HER2-) advanced breast cancer with the alpha-specific phosphatidylinositol-3-kinase (PI3K) inhibitor alpelisib significantly improves progression-free survival, according to late-breaking results reported at ESMO 2018.

22 Oct 2018

Study highlights existence of barriers to early clinical trial access for adolescents and young adults

Young cancer patients at the crossroads of childhood and adulthood seem to be stuck in a treatment impasse. A study to be presented at the ESMO 2018 Congress in Munich, has highlighted the existence of barriers to the inclusion of 12 to 25-year-olds in both adult and pediatric early phase clinical trials, suggesting a need for more tailored approaches to give this patient population better access to therapeutic innovation.

22 Oct 2018

ApoE4 gene linked with chronic inflammation increases risk for Alzheimer's disease

While it is widely shown that possessing the ApoE4 gene is the major genetic risk factor of Alzheimer's disease, not all ApoE4 carriers develop AD.

20 Oct 2018

Immunotherapy medicine found to be effective in treating uveitis

A team of researchers from the UCH CEU's Biomedical Sciences Institute has tested the efficiency of Bevacizumab, medicine used against cancer and in ophtalmology, to treat uveítis, thus stopping the inflammation from spreading.

19 Oct 2018

Scientists receive $5.1 million grant to develop stem cell-based therapy for blinding retinal conditions

Scientists at the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and the Stein Eye Institute have been awarded a $5.1 million grant from the California Institute for Regenerative Medicine to advance the development of a novel therapy for blinding retinal conditions.

19 Oct 2018

Study finds link between refined soluble fibers, gut microbiota and liver cancer

Many of the processed foods we find on grocery store shelves have been loaded up with highly refined soluble fibers such as inulin, a popular probiotic that recently received approval from the Food and Drug Administration to be marketed as health-promoting.

19 Oct 2018

Antidepressant treatment may lead to improvements in sleep quality of patients with depression

In a study of 15 patients affected by major depressive disorder and complaining of insomnia, initiating treatment with vortioxetine for their depressive symptoms led to significant improvements in subjective sleep quality and daytime sleepiness.

17 Oct 2018

Researchers find opportunity to control salt-sensitive hypertension without exercising

Couch potatoes rejoice -- there might be a way to get the blood pressure lowering benefits of exercise in pill form.

16 Oct 2018

Yale researchers develop way to attack RNA with small-molecule drugs

Yale researchers have developed a way to target RNA with small-molecule drugs, creating a new method for tapping into a vast number of biological mechanisms critical to metabolism and gene expression.

15 Oct 2018

Thalamus controls development of normal sleep and waking states, study finds

Consciousness requires continuous, internally generated activity in the brain. The modulation of this activity is the basis of the electroencephalogram (EEG) and of generation of sleep, dreams, and perception.

12 Oct 2018

Scientists find new way to help asthmatics breathe more easily

Around the globe, an estimated 235 million people suffer from asthma. Most people are able to manage their symptoms and live healthy, active lives. However, for some, current treatments are not effective. Managing symptoms can be difficult because triggers are lurking everywhere.

12 Oct 2018

Researchers unravel fresh clues as to how kidney stones form

Kidney stones--solid, pebble-like grit that forms when too much of certain minerals like calcium are in the urine--can strike men, women, and increasingly, children, and the presence and pain of stones afflicts more than 12 percent of the world's population.

11 Oct 2018

Research team awarded $3.6 million to assess safety of genome editing

As genome editing technologies quickly advance toward clinical therapies, they are raising hopes of a completely new way to treat disease. They are also bringing to light a number of challenges that need to be addressed before potential treatments can be widely used in patients.

11 Oct 2018

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Researchers in the Department of Physiology & Biophysics at the University of California, Irvine School of Medicine have discovered the molecular basis for a therapeutic action of an ancient herbal medicine used across Africa to treat various illnesses, including epilepsy.

10 Oct 2018

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis.

10 Oct 2018

Study: Sarcoma patients poorly informed about risk of interactions with anti-cancer drugs

Sarcoma patients show great openness to the use of complementary alternative medicines (CAMs) for supportive care, but they are poorly informed about safety issues and risk of interactions with anti-cancer drugs, a study to be presented at ESMO 2018 reported.

10 Oct 2018

Targeting a protein could be key for suppressing breast cancer metastasis, study suggests

A new study by University of Kentucky Markey Cancer Center researchers suggests that targeting a protein known as collagen XIII could be key for suppressing breast cancer metastasis.

9 Oct 2018

Pharmacology News and Research

Latest Pharmacology News and Research

Targeting specific signaling pathway could provide new avenue for treating fetal alcohol syndrome

New partnership aims to tackle cancer health disparities

SLU researcher seeks to find solutions for 'chemo brain' symptoms and side effects of opioids

Study: Targeting specific genomic mutation in breast cancer improves survival

Study highlights existence of barriers to early clinical trial access for adolescents and young adults

ApoE4 gene linked with chronic inflammation increases risk for Alzheimer's disease

Immunotherapy medicine found to be effective in treating uveitis

Scientists receive $5.1 million grant to develop stem cell-based therapy for blinding retinal conditions

Study finds link between refined soluble fibers, gut microbiota and liver cancer

Antidepressant treatment may lead to improvements in sleep quality of patients with depression

Researchers find opportunity to control salt-sensitive hypertension without exercising

Yale researchers develop way to attack RNA with small-molecule drugs

Thalamus controls development of normal sleep and waking states, study finds

Scientists find new way to help asthmatics breathe more easily

Researchers unravel fresh clues as to how kidney stones form

Research team awarded $3.6 million to assess safety of genome editing

Molecular mechanisms behind therapeutic action of ancient herbal medicine discovered

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

Study: Sarcoma patients poorly informed about risk of interactions with anti-cancer drugs

Targeting a protein could be key for suppressing breast cancer metastasis, study suggests

Industry Focus - Biopharma eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

Pharmacology News and Research

Latest Pharmacology News and Research

Industry Focus - Biopharma eBook

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Bioprocess Efficiency with Cell Density Monitoring

Exploring electron microscopy for plant and microbial imaging at the John Innes Centre

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