Pharmacology News and Research

Latest Pharmacology News and Research

Study finds new enzyme that lays foundations for allergic immune response

While in search of the causes of allergies and asthma, a chance discovery has yielded new clues: researchers led by Dr Marcus Peters have ascertained that the enzyme guanylate cyclase in cells lays the foundations for the type of immune response.

23 Jul 2018

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

PureTech Health plc, a clinical-stage biopharmaceutical company developing novel medicines focused on the Brain-Immune-Gut Axis, today announced that it has entered into a multiyear collaboration with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., to advance PureTech's milk-derived exosome platform technology for the oral administration of Roche's antisense oligonucleotide platform.

20 Jul 2018

Researchers to study molecular mechanisms behind susceptibility of males to autism

Neurodevelopmental disorders such as autism spectrum disorder and intellectual disability are more prevalent in males than females.

20 Jul 2018

ZHX2 protein could offer a new treatment strategy for kidney cancer

University of North Carolina Lineberger Comprehensive Cancer Center scientists have uncovered a potential therapeutic target for kidney cancers that have a common genetic change.

20 Jul 2018

Study: Binge drinking impairs working memory in adolescent brain

A new study from researchers at Columbia University Irving Medical Center found that binge drinking impairs working memory in the adolescent brain. The study, in mice, explains why teenagers who binge drink are 15 times more likely to become alcoholics during adulthood.

19 Jul 2018

Therapy dogs found to be effective in reducing ADHD symptoms in children

In a first of its kind randomized trial, researchers from the UCI School of Medicine found therapy dogs to be effective in reducing the symptoms of attention deficit/hyperactivity disorder in children.

19 Jul 2018

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

Scientists have found that deleting a single gene in a particular strain of gut bacteria causes changes in metabolism and reduced weight gain in mice, according to a study in the journal eLife.

18 Jul 2018

New review examines cannabinoids' potential for direct treatment of cancer

Previous research has shown that cannabinoids can help lessen side effects of anti-cancer therapies. Now a new British Journal of Pharmacology review has examined their potential for the direct treatment of cancer.

18 Jul 2018

Plant-based products fail to have positive impact on blood pressure during clinical studies

In the high-pressure world of lowering hypertension, a surprising favorite isn't standing up too well in clinical trials.

17 Jul 2018

Olfactory receptors play pathophysiological role in all organs than merely smell perception

Numerous studies to date have shown that olfactory receptors are relevant not only for smell perception, but that they also play a significant physiological and pathophysiological role in all organs.

16 Jul 2018

Sodium nitroprusside treatment prevents schizophrenia symptoms in animal model

Researchers at the Federal University of São Paulo in Brazil have tested a treatment with sodium nitroprusside in a strain of rats that spontaneously develop some of the symptoms associated with schizophrenia.

12 Jul 2018

Novel informatics tool helps predict genomic features associated with specific drug responses

The rise of genomics, the shift from considering genes singly to collectively, is adding a new dimension to medical care; biomedical researchers hope to use the information contained in human genomes to make better predictions about individual health, including responses to therapeutic drugs.

12 Jul 2018

Researchers elucidate role of mutations in deadly brain cancer

Researchers from the University of North Carolina Lineberger Comprehensive Cancer Center have discovered how different mutations in a specific gene help drive glioblastoma, the most lethal form of brain cancer.

11 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

Through x-ray crystallography and kinase-inhibitor specificity profiling, University of California San Diego School of Medicine researchers, in collaboration with researchers at Peking University and Zhejiang University, reveal that curcumin, a natural occurring chemical compound found in the spice turmeric, binds to the kinase enzyme dual-specificity tyrosine-regulated kinase 2 at the atomic level.

10 Jul 2018

New technique paves way for safer medicines without side effects

A new technique for precisely targeting molecules within cells is paving the way for safer medicines that are free of side effects.

9 Jul 2018

Fourth-generation retinoid may have improved efficacy and safety profile to treat acne

Topical retinoids, which target retinoic acid receptors, are commonly used to treat acne. New research published in theBritish Journal of Dermatologyreveals that trifarotene, a fourth-generation retinoid with potent and selective activity against only one particular retinoic acid receptor, may have an improved efficacy and safety profile compared with less selective retinoids.

6 Jul 2018

Pharmacology News and Research

Latest Pharmacology News and Research

Study finds new enzyme that lays foundations for allergic immune response

PureTech Health collaborates with Roche to advance oral administration of antisense oligonucleotides

Researchers to study molecular mechanisms behind susceptibility of males to autism

ZHX2 protein could offer a new treatment strategy for kidney cancer

Study: Binge drinking impairs working memory in adolescent brain

Therapy dogs found to be effective in reducing ADHD symptoms in children

Deleting single gene in gut bacteria affects metabolism, reduces weight gain in mice

New review examines cannabinoids' potential for direct treatment of cancer

Plant-based products fail to have positive impact on blood pressure during clinical studies

Olfactory receptors play pathophysiological role in all organs than merely smell perception

Sodium nitroprusside treatment prevents schizophrenia symptoms in animal model

Novel informatics tool helps predict genomic features associated with specific drug responses

Researchers elucidate role of mutations in deadly brain cancer

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers use x-ray crystallography to reveal how curcumin inhibits cancer

New technique paves way for safer medicines without side effects

Fourth-generation retinoid may have improved efficacy and safety profile to treat acne

Researchers discover genetic marker associated with salt sensitivity of blood pressure

Innovative synthetic technique opens door to new world of cutting-edge medicinal compounds

New method separates circulating tumor cells from blood samples using sound waves

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