Pharmacology News and Research

Latest Pharmacology News and Research

Adding energy drinks to alcohol may exacerbate negative effects of binge drinking

A key ingredient of energy drinks could be exacerbating some of the negative effects of binge drinking according to a new study.

14 Aug 2018

Researchers discover new approach to alleviate chronic itch

Two receptors in the spinal cord and the right experimental drug: Researchers at the University of Zurich have discovered a new approach that suppresses itch.

14 Aug 2018

New strategy accelerates, automates process of prototype molecule optimization

The search for new medicinal molecules with predetermined properties is a rather complex, expensive and time-consuming process, especially in oncology.

14 Aug 2018

Brown University researchers reveal key physical properties of 'giant' cancer cells

Polyploidal cancer cells--cells that have more than two copies of each chromosome--are much larger than most other cancer cells, are resistant to chemotherapy and radiation treatments and are associated with disease relapse.

14 Aug 2018

Oxidative Stress Hampers Blood Vessel Dilation in Men

Higher levels of oxidative stress in males results in lower levels of cofactor BH needed to make the powerful blood vessel dilator nitric oxide.

13 Aug 2018

New findings pave way for novel, improved drugs to treat psychiatric disorders

Researchers at Columbia University Irving Medical Center have found new evidence of how certain transport proteins are working at the molecular level, paving the way for new, improved drugs to treat psychiatric disorders.

9 Aug 2018

Study: Exercise can help prevent relapses into cocaine addiction

Exercise can help prevent relapses into cocaine addiction, according to new research led by the University at Buffalo's Panayotis (Peter) Thanos, PhD.

9 Aug 2018

Scientists identify drug that could reverse pulmonary arterial hypertension

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial hypertension, a severe lung disease with a five-year survival rate of 50 percent.

9 Aug 2018

New review examines potential of medicinal cannabis to help treat intractable epilepsy

A new British Journal of Clinical Pharmacology review examines the potential of medicinal cannabis--or medical marijuana--for helping patients with intractable epilepsy, in which seizures fail to come under control with standard anticonvulsant treatment.

8 Aug 2018

New nuclear medicine test could improve care of patients with type 1 diabetes

Researchers have discovered a new nuclear medicine test that could improve care of patients with type 1 diabetes. The new positron emission tomography imaging method could measure beta-cell mass, which would greatly enhance the ability to monitor and guide diabetes therapies.

3 Aug 2018

Mushrooms from the Far East area could be used to design novel anti-cancer drugs

Mushrooms from the Far East area contain the natural chemical compounds, which could be used for the design of the novel drugs with highly specific anti-tumor activities and low-toxicity.

2 Aug 2018

Rutgers researcher receives $100,000 grant to explore T-cell acute lymphoblastic leukemia

A one-year, $100,000 grant awarded to Rutgers Cancer Institute of New Jersey resident researcher Daniel Herranz Benito, PhD, will support exploration into an aggressive blood cancer that impacts both children and adults – T-cell acute lymphoblastic leukemia.

2 Aug 2018

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

A new drug-delivery technology which uses red blood cells to shuttle nano-scale drug carriers, called RBC-hitchhiking, has been found in animal models to dramatically increase the concentration of drugs ferried precisely to selected organs, according to a study published in Nature Communications this month by researchers from the Perelman School of Medicine at the University of Pennsylvania.

2 Aug 2018

Researchers explore influence of dietary nitrate on cognitive function in veterans with GWI

Glenn Wylie, DPhil, and Jorge Serrador, PhD, have won an award from the Rutgers Brain Health Institute. The grant funds a collaborative study between the Department of Pharmacology, Physiology, and Neuroscience at Rutgers New Jersey Medical School and Kessler Foundation.

1 Aug 2018

Progesterone and lipoic acid combination ameliorates death of photoreceptors in the retina

Retinitis pigmentosa is a rare and hereditary neurodegenerative disease which causes vision loss due to the death of photoreceptors in the retina, and for which there is currently no treatment.

31 Jul 2018

Targeting mossy cells may offer new strategy for treating brain disorders

A small population of brain cells deep in a memory-making region of the brain controls the production of new neurons and may have a role in common brain disorders, according to a study from scientists at the University of North Carolina School of Medicine.

27 Jul 2018

Experts describe role of quantitative systems pharmacology in first-in-human clinical trials

Certara, the global leader in model-informed drug development, regulatory science, market access and real-world evidence services, announced today that Clinical Pharmacology & Therapeutics has published its "Letter to the Editor" describing the important role that quantitative systems pharmacology can play in defining dosing criteria for first-in-human clinical trials, together with the European Medicines Agency's response.

26 Jul 2018

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Inflammation is part of the body's natural healing process. But when it becomes chronic, inflammation can lead to cancer, Alzheimer's disease and other conditions.

26 Jul 2018

Anti-cancer gene may switch side and promote cancer growth, shows study

It doesn't often happen that army generals switch sides in the middle of a war, but when cancer's attack is underway, it may even cause a gene that acts as the body's master defender to change allegiance.

26 Jul 2018

UVA researchers discover how obesity may trigger harmful inflammation

New research from the University of Virginia School of Medicine explains why obesity causes harmful inflammation that can lead to diabetes, clogged arteries and other health problems. Doctors may be able to use this knowledge to battle these chronic diseases and others driven by damaging inflammation.

24 Jul 2018

Pharmacology News and Research

Latest Pharmacology News and Research

Adding energy drinks to alcohol may exacerbate negative effects of binge drinking

Researchers discover new approach to alleviate chronic itch

New strategy accelerates, automates process of prototype molecule optimization

Brown University researchers reveal key physical properties of 'giant' cancer cells

Oxidative Stress Hampers Blood Vessel Dilation in Men

New findings pave way for novel, improved drugs to treat psychiatric disorders

Study: Exercise can help prevent relapses into cocaine addiction

Scientists identify drug that could reverse pulmonary arterial hypertension

New review examines potential of medicinal cannabis to help treat intractable epilepsy

New nuclear medicine test could improve care of patients with type 1 diabetes

Mushrooms from the Far East area could be used to design novel anti-cancer drugs

Rutgers researcher receives $100,000 grant to explore T-cell acute lymphoblastic leukemia

RBC-hitchhiking method increases concentration of drugs ferried to selected organs

Researchers explore influence of dietary nitrate on cognitive function in veterans with GWI

Progesterone and lipoic acid combination ameliorates death of photoreceptors in the retina

Targeting mossy cells may offer new strategy for treating brain disorders

Experts describe role of quantitative systems pharmacology in first-in-human clinical trials

Newly identified target may lead to discovery of treatments for chronic inflammatory diseases

Anti-cancer gene may switch side and promote cancer growth, shows study

UVA researchers discover how obesity may trigger harmful inflammation

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