Pharmacology News and Research

Latest Pharmacology News and Research

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

More than 100 million people worldwide take selective serotonin reuptake inhibitors (SSRIs), such as Prozac and Zoloft, to treat depression, anxiety and related conditions, but these drugs have a common and mysterious side effect: they can worsen anxiety in the first few weeks of use, which leads many patients to stop treatment.

25 Aug 2016

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

An atomic level analysis has revealed how two classes of calcium channel blockers, widely prescribed for heart disease patients, produce separate therapeutic effects through their actions at different sites on the calcium channel molecule.

25 Aug 2016

New noninvasive treatment option improves quality of life in patients with essential tremor

Treatment with MRI-guided focused ultrasound significantly improves tremors and quality of life in patients with essential tremor (ET), the most common movement disorder, according to a study published in the August 25 issue of the New England Journal of Medicine.

25 Aug 2016

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss.

23 Aug 2016

Researcher aims to shed new light on inner workings of the retina

One of the more studied parts of the human anatomy, the retina -- the neural layer at the back of the eye that senses light -- still has secrets to reveal.

23 Aug 2016

Research offers new insights into sleep/awake patterns in animals

Research from University of California, Irvine scientists and their colleagues offers new insights into why many animals sleep at night and are active during the day, while others do the reverse.

23 Aug 2016

New study examines effectiveness of pictogram labels on medication-related road traffic crash risk

A new study questions the effectiveness of using pictogram message on the labels of anxiety and sleep medications that interfere with driving - an approach this is currently implemented across France.

22 Aug 2016

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Using technology they developed, UT Southwestern Medical Center researchers have identified a previously unknown role of a certain class of proteins: as regulators of gene activity and RNA processing.

16 Aug 2016

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

By identifying new compounds that selectively block mitochondrial respiration in pathogenic fungi, Whitehead Institute scientists have identified a potential antifungal mechanism that could enable combination therapy with fluconazole, one of today's most commonly prescribed fungal infection treatments.

11 Aug 2016

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Many cancers only become a mortal danger if they form metastases elsewhere in the body. Such secondary tumours are formed when individual cells break away from the main tumour and travel through the bloodstream to distant areas of the body.

11 Aug 2016

Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

It is known that people who have attempted suicide have ongoing inflammation in their blood and spinal fluid. Now, a collaborative study from research teams in the U.S., Sweden and Australia published in Translational Psychiatry shows that suicidal patients have a reduced activity of an enzyme that regulates inflammation and its byproducts.

10 Aug 2016

UA experts offer advice on choosing right pair of sunglasses

Experts from the University of Alicante have found that prolonged exposure to the sun increases the chance of developing alterations in the lens by 4%. Choosing the right pair of sunglasses can reduce such complications.

9 Aug 2016

Novel compound holds potential for next-generation prostate cancer treatment

In the search for new ways to attack recurrent prostate cancer, researchers at Duke Health report that a novel compound appears to have a unique way of blocking testosterone from fueling the tumors in mice.

8 Aug 2016

Gasotransmitters in the body could potentially be used to develop new drugs

Gases once thought of only as environmental pollutants are now known to be produced by the body. They could potentially be used to develop drugs to treat diseases including heart failure and cancer.

8 Aug 2016

Penn researchers develop computer model for designing drug-delivery nanocarriers

A team of University of Pennsylvania researchers has developed a computer model that will aid in the design of nanocarriers, microscopic structures used to guide drugs to their targets in the body.

5 Aug 2016

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Combinations of Food and Drug Administration-approved drugs protect against the loss of cells required for vision in a mouse model of blinding retinal diseases.

4 Aug 2016

Scientists use animal model to gain better understanding of cocaine addiction

Scientists at Wake Forest Baptist Medical Center are one step closer to understanding what causes cocaine to be so addictive. The research findings are published in the current issue of the Journal of Neuroscience.

2 Aug 2016

New review examines potential of antioxidant therapies to combat neurodegenerative disorders

A new review examines the potential of antioxidant approaches for the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis.

2 Aug 2016

University of Utah investigators receive $25 million grant to improve clinical research

Investigators at the University of Utah School of Medicine's Data Coordinating Center have been awarded a seven-year, $25 million grant from the National Center for Advancing Translational Sciences of the National Institutes of Health, to form one of three Trial Innovation Centers to improve clinical research.

29 Jul 2016

Blood pressure hormone system important for cardiovascular health can promote obesity

New research by University of Iowa scientists helps explain how a hormone system often targeted to treat cardiovascular disease can also lower metabolism and promote obesity.

29 Jul 2016

Pharmacology News and Research

Latest Pharmacology News and Research

UNC researchers map anxiety circuit in the brain that may explain side effects of antidepressants

Atomic level analysis reveals how two classes of calcium channel blockers produce different effects

New noninvasive treatment option improves quality of life in patients with essential tremor

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

Researcher aims to shed new light on inner workings of the retina

Research offers new insights into sleep/awake patterns in animals

New study examines effectiveness of pictogram labels on medication-related road traffic crash risk

Newfound role for PARP proteins could lead to therapeutic opportunities for cancer

Scientists identify potential mechanism that paves way for improved treatment of fungal infections

Scientists clarify how tumour cells kill specific cells in vascular wall to establish metastases

Study finds reduced activity of ACMSD enzyme in people with suicidal behavior

UA experts offer advice on choosing right pair of sunglasses

Novel compound holds potential for next-generation prostate cancer treatment

Gasotransmitters in the body could potentially be used to develop new drugs

Penn researchers develop computer model for designing drug-delivery nanocarriers

Combinations of FDA-approved drugs may prevent vision loss linked to retinal degeneration

Scientists use animal model to gain better understanding of cocaine addiction

New review examines potential of antioxidant therapies to combat neurodegenerative disorders

University of Utah investigators receive $25 million grant to improve clinical research

Blood pressure hormone system important for cardiovascular health can promote obesity

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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