Pharmacology News and Research

Latest Pharmacology News and Research

Females respond differently when isolated from social group, study finds

While male and female mice have similar responses to physical stress, research from the Hotchkiss Brain Institute at the University of Calgary, Canada, suggests females, not males, feel stressed when alone.

12 Oct 2016

New review questions safety of estrogen replacement therapy

Although individuals often consume natural products because of their potential health benefits, a new review indicates that it is not clear whether the benefits of plant-derived compounds that mimic estrogen outweigh the possible health risks.

11 Oct 2016

Study finds new therapeutic target to prevent progression of rare blood cancer

In a laboratory study, Upstate Medical University researcher Golam Mohi, Ph.D., his graduate student Yue Yang, and colleagues, have found that the loss of gene EZH2 promotes the development of Myelofibrosis (MF) in mice.

7 Oct 2016

BUSM researchers identify new therapeutic target for treating compulsive binge eating

A new therapeutic target for the treatment of compulsive binge eating has been identified by researchers at Boston University School of Medicine.

6 Oct 2016

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

As demand for the widely used blood thinning drug heparin continues to grow, experts worry of possible shortages of the essential medication.

6 Oct 2016

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

Many types of cancer become drug resistant, making them difficult to treat. Researchers with University of California San Diego School of Medicine and Moores Cancer Center have identified a strategy to selectively sensitize certain cancer cells to radiation therapy that may improve tumor control and reduce treatment-related side effects.

5 Oct 2016

BUSM scientists discover new strategy to treat colon cancers driven by mutant KRAS genes

Researchers from Boston University School of Medicine have discovered a possible strategy to treat colon cancers that are caused by the mutant KRAS gene, which is responsible for approximately half of all colon cancer cases.

4 Oct 2016

Blocking production of key receptor may reduce effects of cigarette smoke toxicity, study finds

A Duke University-led study shows how exposure to the particulate matter from cigarette smoke may affect early development in zebrafish embryos and increases the risk of neurological disorders and physical deformities.

4 Oct 2016

UEF research shows retinal changes may be detected earlier than brain changes

Diseases of the central nervous system (CNS) may manifest as pathological changes in the retina of the eye.

3 Oct 2016

Alternative therapies appear to be effective in ameliorating IBS symptoms

A new review looks at the evidence behind the effectiveness of complementary or alternative therapies-including probiotics, prebiotics, synbiotics, fiber, and herbal medicinal products-for the treatment of bowel disorders such as irritable bowel syndrome (IBS), functional constipation, and ulcerative colitis.

3 Oct 2016

Researchers suggest need for human studies to examine effects of cannabinoid use during pregnancy

In this new era of legalized marijuana, far too little research has been conducted on the effect of cannabis on the development of human embryos, say researchers at Georgetown University Medical Center who scoured medical literature on the topic and found what they say is worrisome animal research.

30 Sep 2016

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

The Alzheimer's Drug Discovery Foundation announces a $2.1 million grant awarded to R. Scott Turner, MD, PhD, of Georgetown University Medical Center to conduct a phase II clinical trial of low-dose nilotinib (marketed as Tasigna for use as a cancer therapy) in patients with Alzheimer's disease.

29 Sep 2016

Bioactive compound from neem plant shows promising effects on prostate cancer

A team of international researchers led by Associate Professor Gautam Sethi from the Department of Pharmacology at the Yong Loo Lin School of Medicine at the National University of Singapore has found that nimbolide, a bioactive terpenoid compound derived from Azadirachta indica or more commonly known as the neem plant, could reduce the size of prostate tumour by up to 70 per cent and suppress its spread or metastasis by half.

29 Sep 2016

Alcohol produces same neural and molecular changes as rapid antidepressant drugs

Can having a few drinks help people with clinical depression feel better? Yes. At least in terms of biochemistry.

28 Sep 2016

Researchers aim to discover new treatments for triple-negative breast cancer

The precision medicine approach involving DNA sequencing to pinpoint specific alterations that can be targeted with anti-cancer therapies is becoming an alternate treatment avenue for those with poor-responding cancers.

28 Sep 2016

Cross-disciplinary concepts may lead to effective, personalised cancer treatments

It is not only tumours and metastases that differ in each type of cancer and each individual sufferer but also receptors in cells.

27 Sep 2016

NIGHTSEA and EMS nominate Dr. Sarah Petersen for 2016 KEY Award

NIGHTSEA, creators and manufacturers of the innovative Stereo Microscope Fluorescence Adapter (SFA), and Electron Microscopy Sciences (EMS) are pleased to award the second annual KEY Award for New Faculty to Dr. Sarah Petersen of Kenyon College.

From NIGHTSEA 24 Sep 2016

Human pluripotent stem cells may revolutionize drug discovery in heart disease

Coaxing stem cells from patients to become heart cells may help clinicians personalize drug treatments and prevent heart-related toxicity.

20 Sep 2016

Study quantifies burden of clinically impactful ADRs in general adult population

In a study of 1000 adult patients with unplanned admission to a tertiary hospital in Singapore, the prevalence of adverse drug reactions (ADRs) at the time of admission was 12.4 percent, and the prevalence of ADRs causing admission to the hospital was 8.1 percent.

19 Sep 2016

UC Irvine study shows how YHS effectively treats different forms of pain

Root extracts from the flowering herbal plant Corydalis yanhusuo, or YHS, has widely used for centuries as a pain treatment. Yet few studies have investigated how it works on different forms of pain, and little is known about its molecular mechanisms.

14 Sep 2016

Pharmacology News and Research

Latest Pharmacology News and Research

Females respond differently when isolated from social group, study finds

New review questions safety of estrogen replacement therapy

Study finds new therapeutic target to prevent progression of rare blood cancer

BUSM researchers identify new therapeutic target for treating compulsive binge eating

Study finds blood thinning drugs derived from cattle and pigs have equivalent anti-clotting properties

Researchers identify new strategy to selectively sensitize cancer cells to radiation therapy

BUSM scientists discover new strategy to treat colon cancers driven by mutant KRAS genes

Blocking production of key receptor may reduce effects of cigarette smoke toxicity, study finds

UEF research shows retinal changes may be detected earlier than brain changes

Alternative therapies appear to be effective in ameliorating IBS symptoms

Researchers suggest need for human studies to examine effects of cannabinoid use during pregnancy

ADDF awards $2.1 million grant for clinical study of cancer drug in Alzheimer's patients

Bioactive compound from neem plant shows promising effects on prostate cancer

Alcohol produces same neural and molecular changes as rapid antidepressant drugs

Researchers aim to discover new treatments for triple-negative breast cancer

Cross-disciplinary concepts may lead to effective, personalised cancer treatments

NIGHTSEA and EMS nominate Dr. Sarah Petersen for 2016 KEY Award

Human pluripotent stem cells may revolutionize drug discovery in heart disease

Study quantifies burden of clinically impactful ADRs in general adult population

UC Irvine study shows how YHS effectively treats different forms of pain

Pittcon Highlights: Pharmaceutical & Biologic eBook

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

Transforming Lab Workflows with Cell Culture Automation

Building Bridges to Scalable Allogeneic Cell Therapy

Edoardo Fabini

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